anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Antikörper

Bezeichnung:
anti-Spectrin, Beta, Non-erythrocytic 2 Antikörper (SPTBN2)
Auf www.antikoerper-online.de finden Sie aktuell 182 Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Antikörper von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 183 Spectrin, Beta, Non-erythrocytic 2 Produkte verfügbar.
Synonyme:
GTRAP41, mKIAA0302, SCA5, Spnb3
Alle Antikörper anzeigen Gen GeneID UniProt
SPTBN2 20743  
SPTBN2 6712 O15020
SPTBN2 29211 Q9QWN8

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Weitere Antikörper gegen Spectrin, Beta, Non-erythrocytic 2 Interaktionspartner

Mouse (Murine) Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Interaktionspartner

  1. TGF-beta (zeige TGFB1 Antikörper)/beta2-spectrin/CTCF (zeige CTCF Antikörper)-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.

  2. Study shows a direct interaction between beta-III spectrin and erythroid ankyrin (zeige ANK1 Antikörper) in the cerebellum and to demonstrate a critical role for beta-III spectrin in maintaining ankyrin R (zeige ANK1 Antikörper) throughout the Purkinje cell dendritic tree.

  3. This study demonistrated that beta-III spectrin is critical for development of purkinje cell dendritic tree and spine morphogenesis.

  4. Beta-III spectrin mutation L253P interferes with binding to Arp1 (zeige APOBEC2 Antikörper) and protein trafficking from the Golgi.

  5. betaIII spectrin disruption impairs synaptogenesis by disturbing the intracellular pathways selectively regulating protein trafficking to the synapse

Human Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Interaktionspartner

  1. Cardiac beta2-spectrin and downstream molecules are regulated in multiple forms of cardiovascular disease via Ca(2+)- and calpain-dependent proteolysis.

  2. This study indicates that high-affinity actin binding of L253P beta-III-spectrin is a likely driver of neurodegeneration.

  3. beta2-Spectrin, a TGF-beta (zeige TGFB1 Antikörper) mediator and signaling molecule, is cleaved and activated by caspase-3 (zeige CASP3 Antikörper)/7, consequently enhancing apoptosis and transcriptional control to determine cell fate upon liver damage.

  4. TGF-beta (zeige TGFB1 Antikörper)/beta2-spectrin/CTCF (zeige CTCF Antikörper)-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.

  5. investigated using either targeted next generation sequencing or trio (zeige TRIO Antikörper)-based exome sequencing and were found to have mutations in three different genes, KCNC3 (zeige KCNC3 Antikörper), ITPR1 (zeige ITPR1 Antikörper) and SPTBN2

  6. First Japanese spinocerebellar ataxia type 5 (SCA5) family with a novel heterozygous three-nucleotide in-frame deletion mutation in the SPTBN2 gene.

  7. A homozygous SPTBN2 nonsense mutation underlying infantile ataxia and psychomotor delay in a human family.

  8. Mutant beta-III spectrin causes mislocalization and dysfunction of mGluR1alpha at dendritic spines.

  9. A novel missense mutation within a SPTBN2 spectrin repeat encoded by exon 12 was found in a family with spinocerebellar ataxia type 5.

  10. the identification of SPARCA1 and normal heterozygous carriers of the stop codon in SPTBN2 provides insights into the mechanism of molecular dominance in SCA5 and demonstrates that the cell-specific repertoire of spectrin subunits

Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Antigen-Profil

Beschreibung des Gens

Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.

Alternative names and synonyms associated with Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

  • spectrin beta, non-erythrocytic 2 (Sptbn2) Antikörper
  • spectrin, beta, non-erythrocytic 2 (SPTBN2) Antikörper
  • spectrin, beta, non-erythrocytic 2 (Sptbn2) Antikörper
  • GTRAP41 Antikörper
  • mKIAA0302 Antikörper
  • SCA5 Antikörper
  • Spnb3 Antikörper

Bezeichner auf Proteinebene für SPTBN2

beta-spectrin 3 , spectrin beta 3 , spectrin beta chain, brain 2 , beta-III spectrin , glutamate transporter EAAT4-associated protein 41 , spectrin beta chain, non-erythrocytic 2 , spectrin, non-erythroid beta chain 2 , spinocerebellar ataxia 5 protein , SPNB-3 , beta SpIII sigma 1 , spectrin-like protein GTRAP41

GENE ID SPEZIES
20743 Mus musculus
6712 Homo sapiens
29211 Rattus norvegicus
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