Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 2150-2200) Antikörper

Produktnummer ABIN7452441

Produktdetails

Target: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Bindungsspezifität: AA 2150-2200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-SPTBN2/SCA5 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 2150 and 2200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-SPTBN2/SCA5 antibody ABIN7450766.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Antigendetails

Target: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Andere Bezeichnung: SPTBN2/SCA5 (SPTBN2 Produkte)

Synonyme: Spnb3 antikoerper, mKIAA0302 antikoerper, GTRAP41 antikoerper, SCA5 antikoerper, spectrin beta, non-erythrocytic 2 antikoerper, spectrin, beta, non-erythrocytic 2 antikoerper, Sptbn2 antikoerper, SPTBN2 antikoerper

Hintergrund: Background: SPTBN2/SCA5 is a member of the beta spectrin gene family and a subunit of the spectrin cytoskeletal scaffolding protein that links the plasma membrane to cytoskeletal actin and functions in cellular shape and organelle organization. SPTBN2/SCA5 has been identified as a Golgi- and vesicle-associated spectrin. Mutations in SPTBN2/SCA5 cause spinocerebellar ataxia type 5 (SCA5), an autosomal dominant disease characterized by progressive incoordination of gait, hand, speech, and eye movements.

Gen-ID: 6712

NCBI Accession: NP_008877

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis