anti-Xenopus laevis Slit Homolog 2 (Drosophila) Antikörper für Enzyme Immunoassay

Recommended Slit Homolog 2 (Drosophila) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Slit Homolog 2 (Drosophila) (SLIT2) Antikörper
  • SLIL3
  • Slit-2
  • Drad-1
  • E030015M03Rik
  • E130320P19Rik
  • Slil3
  • mKIAA4141
  • Slit
  • slil3
  • slit-2
  • slit2-a
  • SLIT2
  • slit homolog 2 (Drosophila)
  • slit (Drosophila) homolog 2
  • slit homolog 2
  • SLIT2
  • Slit2
  • slit2
Epitop
AA 484-500
21
11
10
6
5
4
3
3
3
2
1
1
1
1
1
1
1
Reaktivität
Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus), Tetraodon nigroviridis, Xenopus laevis
99
67
35
2
2
2
1
1
1
1
1
Wirt
Kaninchen
68
26
17
3
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
9
6
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
46
38
38
29
25
13
6
5
5
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5551752
$ 411.18
Zzgl. Versandkosten $45.00

General

Antigen Slit Homolog 2 (Drosophila) (SLIT2) Antikörper
Epitop AA 484-500
(21), (11), (10), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus), Tetraodon nigroviridis, Xenopus laevis
(99), (67), (35), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(68), (26), (17), (3), (2)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(9), (6), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(46), (38), (38), (29), (25), (13), (6), (5), (5), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody is directed against SLIT-2 protein.
Kreuzreaktivität (Details) Species reactivity (expected):Chicken, Mouse, Rat, Bovine, Xenopus laevis.
Species reactivity (tested):Human.
Produktmerkmale Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)
Reinigung Affinity Chromatography
Immunogen Synthetic peptide corresponding aa 484-500 of Human SLIT-2 protein.
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SLIT2 (SLIT2 Antibody Abstract)
Hintergrund SLIT-2 is thought to act as a molecular guidance cue in cellular migration, and its function appears to be mediated by interaction with roundabout homologue receptors. SLIT-1 and SLIT-2 seem to be essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development SLIT-2 may play role in guiding commissural axons once they reach the floor plate by modulating the response to netrin. In vitro, SLIT-2 silences the attractive effect of NTN1 but not its growthstimulatory effect and silencing requires the formation of a ROBO1-DCC complex. In vitro, only commissural axons that crossed the midline responded to SLIT-2. In the developing visual system this protein functions as a repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. SLIT-2 is a secreted protein predominantly expressed in fetal lung and kidney, and adult spinal cord. Weak expression is observed in adult adrenal gland, thyroid, trachea and other tissues examined. Multiple isoforms have been reported for this product.Synonyms: SLIL3, SLIT-2, Slit homolog 2 protein
Gen-ID 9353
NCBI Accession NP_004778
UniProt O94813
Pathways Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise ELISA: 1/1,500 - 1/6,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted 2-8 °C fo one month or (in aliquots) at-20 °C for longer.