anti-Ratte (Rattus) Kin of IRRE Like (Drosophila) Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Kin of IRRE Like (Drosophila) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Kin of IRRE Like (Drosophila) (NEPH1) Antikörper
  • NEPH1
  • 6720469N11Rik
  • Kirrel1
  • Neph1
  • nephrin related
  • kin of IRRE like (Drosophila)
  • Smp_104390
  • Smp_140170
  • KIRREL
  • Kirrel
Reaktivität
Human, Maus, Ratte (Rattus)
40
29
29
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
54
Klonalität
Polyklonal
Konjugat
HRP
7
7
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
31
12
12
11
11
10
10
4
Optionen
Hersteller
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Produktnummer ABIN903761
$ 379.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN903750 IHC (p) WB Biotin Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN873077 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Kin of IRRE Like (Drosophila) (NEPH1) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(40), (29), (29), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(54)
Klonalität
Polyklonal
Konjugat HRP
(7), (7), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(39), (31), (12), (12), (11), (11), (10), (10), (4)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human KIRREL1/NEPH1
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Kirrel1 (NEPH1 Antibody Abstract)
Hintergrund

Neph1(Kirrel) belongs to a family of three closely related transmembrane proteins of the Ig superfamily with a structure similar to that of nephrin. Neph1 consists of a signal peptide, five Ig-like C2-type domains with the middle domain overlapping with a PKD-like domain, an RGD sequence, a transmembrane domain and a cytoplasmic tail. Neph1 is abundantly expressed in the kidney, specifically expressed in podocytes of kidney glomeruli, and plays a significant role in the normal development and function of the glomerular permeability. Neph1 interacts with nephrin in vitro and in vivo, and able to stimulate transcriptional activation in a model system, such as the activation the transcription factor AP-1 via the stimulation of a MAPK module. Neph1 is crucial for the integrity of the slit diaphragm, as Neph1 gene knockout mice results in effacement of glomerular podocytes, heavy proteinuria, and early postnatal death..Tissue specificity:Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.

Subcellular location: Extracellular


Synonyms: Kin of IRRE like Drosophila,Kin of IRRE like,Kin of IRRE like protein 1,Kin of IRRE-like protein 1,Kin of irregular chiasm like protein 1,Kin of irregular chiasm-like protein 1,KIRR1_HUMAN,Kirrel,MGC129542,MGC129543,NEPH 1,NEPH1,Nephrin like protein 1,Nephrin related,Nephrin-like protein 1,KIRR1_HUMAN.
Gen-ID 55243
Pathways Regulation of Actin Filament Polymerization

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise WB(1:100-1000), IHC-P(1:100-500)
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Konservierungsmittel Gentamicin sulfate
Vorsichtsmaßnahmen This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Lagerung -20 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months