anti-Ratte (Rattus) Kin of IRRE Like (Drosophila) Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended Kin of IRRE Like (Drosophila) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Kin of IRRE Like (Drosophila) (NEPH1) Antikörper
  • NEPH1
  • 6720469N11Rik
  • Kirrel1
  • Neph1
  • nephrin related
  • kin of IRRE like (Drosophila)
  • Smp_104390
  • Smp_140170
  • KIRREL
  • Kirrel
Reaktivität
Human, Maus, Ratte (Rattus)
40
29
29
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
54
Klonalität
Polyklonal
Konjugat
Cy3
7
7
3
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
40
31
12
12
11
10
10
10
5
Optionen
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Produktnummer ABIN903751
$ 379.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN903762 IF (p) Cy5 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903746 IF (p) Alexa Fluor 555 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903752 IF (p) Cy5.5 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903753 IF (p) Alexa Fluor 350 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903754 IF (p) Alexa Fluor 488 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903755 IF (p) Alexa Fluor 647 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903757 IF (p) FITC Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN903756 IF (p) Cy7 Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN873077 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN2803578 IF (p) Alexa Fluor 594 Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Kin of IRRE Like (Drosophila) (NEPH1) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(40), (29), (29), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(54)
Klonalität
Polyklonal
Konjugat Cy3
(7), (7), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(40), (31), (12), (12), (11), (10), (10), (10), (5)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human KIRREL1/NEPH1
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Kirrel1 (NEPH1 Antibody Abstract)
Hintergrund

Neph1(Kirrel) belongs to a family of three closely related transmembrane proteins of the Ig superfamily with a structure similar to that of nephrin. Neph1 consists of a signal peptide, five Ig-like C2-type domains with the middle domain overlapping with a PKD-like domain, an RGD sequence, a transmembrane domain and a cytoplasmic tail. Neph1 is abundantly expressed in the kidney, specifically expressed in podocytes of kidney glomeruli, and plays a significant role in the normal development and function of the glomerular permeability. Neph1 interacts with nephrin in vitro and in vivo, and able to stimulate transcriptional activation in a model system, such as the activation the transcription factor AP-1 via the stimulation of a MAPK module. Neph1 is crucial for the integrity of the slit diaphragm, as Neph1 gene knockout mice results in effacement of glomerular podocytes, heavy proteinuria, and early postnatal death..Tissue specificity:Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.

Subcellular location: Extracellular


Synonyms: Kin of IRRE like Drosophila,Kin of IRRE like,Kin of IRRE like protein 1,Kin of IRRE-like protein 1,Kin of irregular chiasm like protein 1,Kin of irregular chiasm-like protein 1,KIRR1_HUMAN,Kirrel,MGC129542,MGC129543,NEPH 1,NEPH1,Nephrin like protein 1,Nephrin related,Nephrin-like protein 1,KIRR1_HUMAN.
Gen-ID 55243
Pathways Regulation of Actin Filament Polymerization

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise IF(IHC-P)(1:50-200)
Kommentare

Exitation/Emission: 512,550nm/570,615nm

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months