anti-Maus Carboxypeptidase B2 (Plasma) Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Carboxypeptidase B2 (Plasma) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Carboxypeptidase B2 (Plasma) (CPB2) Antikörper
  • 1700120C01Rik
  • AI325129
  • CPB1
  • CPB2
  • CPbeat2
  • CPbeta1
  • CPbeta2
  • Cappb1
  • CPU
  • PCPB
  • TAFI
  • 1110032P04Rik
  • 4930405E17Rik
  • AI255929
  • CPR
  • Cpu
  • pCPB
  • capping protein (actin filament) muscle Z-line, beta
  • carboxypeptidase B2 (plasma)
  • Capzb
  • CPB2
  • Cpb2
Reaktivität
Human, Maus, Ratte (Rattus)
155
42
25
2
1
1
1
1
1
Wirt
Kaninchen
83
83
16
Klonalität
Polyklonal
Konjugat
HRP
10
9
7
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
119
17
13
8
7
6
5
5
3
3
2
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN892101
$ 405.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN892100 IHC (p) WB Biotin Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN872886 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Carboxypeptidase B2 (Plasma) (CPB2) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(155), (42), (25), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(83), (83), (16)
Klonalität
Polyklonal
Konjugat HRP
(10), (9), (7), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(119), (119), (17), (13), (8), (7), (6), (5), (5), (3), (3), (2), (2), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CPB2
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CPB2 (CPB2 Antibody Abstract)
Hintergrund

This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues, pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 μg/mL. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.

Synonyms: Carboxypeptidase B like protein, Carboxypeptidase U, CarboxypeptidaseB2, Carboxypeptidase B2, CarboxypeptidaseU, CP B2, CPB 2, CPB2, CPU, PCPB, Plasma carboxypeptidase B, Plasma carboxypeptidase B2, Procarboxypeptidase B, Procarboxypeptidase R, Procarboxypeptidase U, TAFI, Thrombin activable fibrinolysis inhibitor, Thrombin activatable fibrinolysis inhibitor.

Gen-ID 1361
Pathways Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Konservierungsmittel Gentamicin sulfate
Vorsichtsmaßnahmen This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months