C-Type Lectin Domain Family 2, Member I Proteine (CLEC2I)

Bezeichnung:
C-Type Lectin Domain Family 2, Member I Proteine (CLEC2I)
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Synonyme:
Clr-g, Clrg, Dcl1, LCL-1, OCILrP2
alle Proteine anzeigen Gen GeneID UniProt
CLEC2I 93675 Q9WVF9

Weitere Synonyme anzeigen

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Weitere Proteine zu C-Type Lectin Domain Family 2, Member I Interaktionspartnern

Mouse (Murine) C-Type Lectin Domain Family 2, Member I (CLEC2I) Interaktionspartner

  1. Data show OCILRP2 binding to DAP12 (zeige TYROBP Proteine) resulting in Raf (zeige RAF1 Proteine)-MAP kinase (zeige MAPK1 Proteine) pathways activation and T-cell activation.

  2. OCILRP2 is a regulator of dendritic cells maturation and differentiation following TLR4 (zeige TLR4 Proteine) activation.

  3. The electrostatic profile of NKR-P1F (zeige KLRB1F Proteine) is complementary to that of Clr-g, which suggests a plausible interaction mechanism based on contacts between surface sites of opposite potential.

  4. studies reveal a unique functional interaction between two C-type lectins, OCILRP2/Clr-g and NKRP1f (zeige KLRB1F Proteine), during APC (zeige APC Proteine)-mediated T cell costimulation and suggest a role for C-type lectins in maintaining T cell response or memory in vivo

  5. Identification of a novel family of genes, named Clr (zeige CALCR Proteine), encoding C-type lectin-like molecules, which maps in the natural killer (NK) gene complex (NKC) on mouse Chromosome 6.

  6. mouse Nkrp1d and Nkrp1f (zeige KLRB1F Proteine) bind specific C-type lectin-related (Clr (zeige CALCR Proteine)) molecules. Nkrp1d mediated inhibition when recognizing Clrb (zeige CLEC2D Proteine), a molecule expressed in dendritic cells and macrophages. Nkrp1 and Clr (zeige CALCR Proteine) are intertwined in a genetically conserved NKC region.

C-Type Lectin Domain Family 2, Member I (CLEC2I) Protein Überblick

Protein Überblick

Inhibits osteoclast formation. Receptor for KLRB1F. Enhances T-cell activation. Plays a role in splenocyte activation, T-cell responses and IL-2 production.

Alternative names and synonyms associated with C-Type Lectin Domain Family 2, Member I (CLEC2I)

  • C-type lectin domain family 2, member i (Clec2i)
  • Clr-g Protein
  • Clrg Protein
  • Dcl1 Protein
  • LCL-1 Protein
  • OCILrP2 Protein

Bezeichner auf Proteinebene für CLEC2I

C-type lectin 1 , C-type lectin domain family 2 member I , C-type lectin-related protein DCL1 , C-type lectin-related protein G , lymphoid-derived C-type lectin-1 , ocil-related protein 2 , osteoclast inhibitory lectin related protein 2 , osteoclast inhibitory lectin-related protein 2

GENE ID SPEZIES
93675 Mus musculus
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