V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) protein (HIS)

Name: V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS)

Synonyme: CTLO, HAMSV, HRAS1, K-RAS, N-RAS, RASH1, C-H-RAS, H-RASIDX, C-BAS/HAS, C-HA-RAS1, c-H-ras, H-Ras, K-Ras, hras1, rash1, HRAS, ras, N-Ras, c-bas/has, zgc:110250, H-RAS, LOC100227892

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN666969

Produktbeschreibung

Produktmerkmale: HRAS, 1-186aa, Human, His-tag, E.coli

Format: Liquid

Beschreibung: HRAS, also known as GTPase HRas, belongs to the Ras family which function in signal transduction pathways. This protein can bind GTP and GDP, and it has intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. Defects in HRAS are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Recombinant human HRAS protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HMG14, GC104230, v-Ha-ras Harvey rat sarcoma viral oncogene homolog C BAS/HAS, c H ras, C HA RAS1, c has/bas p21 protein, c ras Ki 2 activated oncogene, CTLO, GTP and GDP binding peptide B, H Ras 1, H RASIDX, Ha Ras, Ha Ras1 proto oncoprotein, HAMSV, HRAS, HRAS1, K ras, N ras, p19 H RasIDX protein, p21ras, Ras family small GTP binding protein H Ras, RASH1, Transformation gene oncogene HAMSV, Transforming protein p21, v Ha ras Harvey rat sarcoma viral oncogene homolog, VH Ras, vHa RAS. NCBI no.: NP_001123914

Molekulargewicht: 22.0 kDa (194aa), confirmed by MALDI-TOF.

Anwendungen

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Reinheit: > 90% by SDS - PAGE

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) protein (HIS)