ENPP2 Protein (AA 49-863) (His tag)

Produktnummer ABIN2181007

Produktdetails

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 49-863

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ENPP2 Protein ist gelabelt mit His tag.

Sequenz: AA 49-863

Produktmerkmale: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 94.5 kDa. The protein migrates as 120-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 150 mM NaCl, pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Andere Bezeichnung: ENPP-2 (ENPP2 Produkte)

Synonyme: ATX Protein, ATX-X Protein, AUTOTAXIN Protein, LysoPLD Protein, NPP2 Protein, PD-IALPHA Protein, PDNP2 Protein, Npps2 Protein, PD-Ialpha Protein, Pdnp2 Protein, MGC132047 Protein, atx Protein, zgc:63550 Protein, autotaxin Protein, enpp2 Protein, enpp2a Protein, enpp2b Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog Protein, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog Protein, ENPP2 Protein, Enpp2 Protein, enpp2 Protein, enpp2.L Protein, enpp2.S Protein

Hintergrund: Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.

Molekulargewicht: 94.5 kDa

NCBI Accession: NP_001035181