IL-2 Protein
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- Target Alle IL-2 (IL2) Proteine anzeigen
- IL-2 (IL2) (Interleukin 2 (IL2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLHYKDPAA NKARKEAELA AATAEQ
- Produktmerkmale
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Length (AA): 156
Chromosomal location: 4q26-q27
The ED50 as determined by the dose-dependent stimulation of proliferation of murine D10G4.1 cells is in the range of 0.1-0.5 ng/mL. - Reinheit
- > 98 % by SDS-PAGE. Visualized by silver stain
- Endotoxin-Niveau
- < 0.1 ng per µg of IL-2
- Top Product
- Discover our top product IL2 Protein
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- Kommentare
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Cytokines & Growth Factors
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- The lyophilized IL-2 should be reconstituted in 50 mM acetic acid to a concentration not less than 100 μg/mL. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.
- Buffer
- 50 mM acetic acid
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- 0 °C
- Informationen zur Lagerung
- The lyophilized IL-2, though stable at room temperature, is best stored desiccated below 0 °C. Reconstituted IL-2 should be stored in workingaliquots at -20 °C.
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Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1." in: Biochemical pharmacology, Vol. 92, Issue 2, pp. 312-25, (2014) (PubMed).
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Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1." in: Biochemical pharmacology, Vol. 92, Issue 2, pp. 312-25, (2014) (PubMed).
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- Target
- IL-2 (IL2) (Interleukin 2 (IL2))
- Andere Bezeichnung
- IL-2 (IL2 Produkte)
- Synonyme
- IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
- Hintergrund
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IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 (modified at the C-terminal end) is a 15.5 kDa protein, containing 156 amino acid residues including one intrachain disulfide bond.
Synonyms: IL2, IL-2, TCGF, lymphokine - Molekulargewicht
- 15.5 kDa
- NCBI Accession
- NP_000577, NM_000586
- UniProt
- P60568
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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