anti-Meerschweinchen CAPN10 Antikörper für Western Blotting

Recommended CAPN10 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Calpain 10 (CAPN10) Antikörper
  • CAPN10
  • CANP10
  • NIDDM1
  • AW049679
  • Capn8
  • mKIAA1845
  • calpain 10
  • calpain 10 L homeolog
  • CAPN10
  • capn10.L
  • capn10
  • Capn10
Epitop
N-Term
8
4
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus)
31
9
3
3
3
2
1
1
Wirt
Kaninchen
32
1
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
26
11
7
3
3
3
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN2784913
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2432864 ABIN2784914 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN799450 WB Rabbit AA 44-93 Anmelden zum Anzeigen Polyclonal

General

Antigen Calpain 10 (CAPN10) Antikörper
Epitop N-Term
(8), (4), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus)
(31), (9), (3), (3), (3), (2), (1), (1)
Wirt Kaninchen
(32), (1)
Klonalität
Polyklonal
Applikation Western Blotting (WB)
(26), (11), (7), (3), (3), (3), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CAPN10 Antikörper

Target Details CAPN10 Anwendungsinformationen Handhabung Referenzen für anti-CAPN10 Antikörper (ABIN2784913) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974443.
Sequenz MRAGRGATPA RELFRDAAFP AADSSLFCDL STPLAQFRED ITWRRPQEIC
Homologie Cow: 92%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against CAPN10. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CAPN10

Target Details CAPN10

Produktdetails anti-CAPN10 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CAPN10 Antikörper (ABIN2784913) Bilder zurück nach oben
Antigen
Andere Bezeichnung CAPN10 (CAPN10 Antibody Abstract)
Hintergrund CAPN10 is the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CANP10, NIDDM1
Protein Interaction Partner: EFNB1, FLOT1, PSMA7, FANCC,
Protein Size: 517
Molekulargewicht 58 kDa
Gen-ID 11132
NCBI Accession NM_023085, NP_075573
UniProt Q9HC96
Pathways Positive Regulation of Peptide Hormone Secretion

Anwendungsinformationen

Produktdetails anti-CAPN10 Antikörper Target Details CAPN10 Handhabung Referenzen für anti-CAPN10 Antikörper (ABIN2784913) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 517 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CAPN10 Antikörper Target Details CAPN10 Anwendungsinformationen Referenzen für anti-CAPN10 Antikörper (ABIN2784913) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CAPN10 Antikörper (ABIN2784913)

Produktdetails anti-CAPN10 Antikörper Target Details CAPN10 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Kifagi, Makni, Mnif, Boudawara, Hamza, Rekik, Abid, Rebaï, Granier, Jarraya, Ayadi: "Association of calpain-10 polymorphisms with type 2 diabetes in the Tunisian population." in: Diabetes & metabolism, Vol. 34, Issue 3, pp. 273-8, 2008

Bilder

Produktdetails anti-CAPN10 Antikörper Target Details CAPN10 Anwendungsinformationen Handhabung Referenzen für anti-CAPN10 Antikörper (ABIN2784913) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Calpain 10 (CAPN10) (N-Term) antibody (ABIN2784913) WB Suggested Anti-CAPN10 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: