anti-MAPKSP1 (MAPKSP1) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 Antikörper (MAPKSP1)
Auf www.antikoerper-online.de finden Sie aktuell 59 Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPKSP1 Proteine (19) und MAPKSP1 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 87 MAPKSP1 Produkte verfügbar.
Synonyme:
AW556229, Map2k1ip1, Mapbp, mapksp1, Mp1, PRO0633, Ragulator3, zgc:110207

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anti-Human MAPKSP1 Antikörper:

anti-Mouse (Murine) MAPKSP1 Antikörper:

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Am meisten referenzierte anti-MAPKSP1 Antikörper

  1. Human Monoclonal MAPKSP1 Primary Antibody für WB - ABIN393554 : Sancak, Bar-Peled, Zoncu, Markhard, Nada, Sabatini: Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. in Cell 2010 (PubMed)
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Weitere Antikörper gegen MAPKSP1 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) Interaktionspartner

  1. BCL2 (zeige BCL2 Antikörper) expression in mesennchymal lung cancer cells was induced by ERK1 (zeige MAPK3 Antikörper) activity through the upregulation of the MEK1 (zeige MAP2K1 Antikörper)/ERK1 (zeige MAPK3 Antikörper) scaffold protein (zeige HOMER1 Antikörper) MEK partner-1. Interfering with the MEK1 (zeige MAP2K1 Antikörper)/MP1 (zeige PITRM1 Antikörper)/ERK1 (zeige MAPK3 Antikörper) axis using a MEK1 (zeige MAP2K1 Antikörper) inhibitor or MP1 (zeige PITRM1 Antikörper) depletion repressed BCL2 (zeige BCL2 Antikörper) expression and sensitized MLCCs to chemoradiotherapy.

  2. The present study was aimed at investigating whether the miR (zeige MLXIP Antikörper)-29c binding site single nucleotide polymorphisms within the 3'-UTRs of LAMTOR3 gene affected the gastric cancer risk.

  3. we demonstrate that the MAPK (zeige MAPK1 Antikörper) scaffold protein (zeige HOMER1 Antikörper) MEK partner 1 (MP1) is important for gastrin (zeige GAST Antikörper)-induced phosphorylation of ERK1 (zeige MAPK3 Antikörper) and ERK2 (zeige MAPK1 Antikörper) and that MP1 (zeige PITRM1 Antikörper) promotes gastrin (zeige GAST Antikörper)-induced proliferation of AGS (zeige JAG1 Antikörper)-GR cells

  4. identified polymorphisms in LAMTOR2 (zeige LAMTOR2 Antikörper) and LAMTOR3 do not seem to play a relevant role in breast cancer

  5. A complex encoded by the MAPKSP1, ROBLD3 (zeige LAMTOR2 Antikörper), and c11orf59 (zeige LAMTOR1 Antikörper) genes interacts with the Rag GTPases, recruits them to lysosomes, and is essential for mTORC1 activation

  6. We investigated the neuroprotective effect of glial-derived neurotrophic factor (GDNF) upon alcohol-exposed B92 cultures, as well as the role of the cytoskeleton and mitogen-activated protein kinase (zeige MAPK1 Antikörper) (MAPK (zeige MAPK1 Antikörper)) pathways in this effect.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) Interaktionspartner

  1. This novel mechanism for localization of intracellular Leishmania amazonensis-mediated ERK1/2 phosphorylation required the endosomal scaffold protein MP1 and localized to Leishmania amazonensis parasitophorous vacuoles.

  2. We show an essential function for late endosomes carrying the p14 (zeige PCOLCE Antikörper)-MP1 (LAMTOR2 (zeige LAMTOR2 Antikörper)/3) complex in focal adhesion dynamics.

  3. Data indicate that LAMTOR3 protein is stabilized by associating with LAMTOR2 (zeige LAMTOR2 Antikörper).

  4. A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.

  5. MP1 and the MP1*P14 (zeige PCOLCE Antikörper) complex have the potential to differentially modulate activating and inhibiting signals in the Raf (zeige RAF1 Antikörper)-MKK1 (zeige MAP2K1 Antikörper)/2-ERK1/2 (zeige MAPK1/3 Antikörper) pathway.

MAPKSP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.

Alternative names and synonyms associated with MAPKSP1

  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3) Antikörper
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (Lamtor3) Antikörper
  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (lamtor3) Antikörper
  • AW556229 Antikörper
  • Map2k1ip1 Antikörper
  • Mapbp Antikörper
  • mapksp1 Antikörper
  • Mp1 Antikörper
  • PRO0633 Antikörper
  • Ragulator3 Antikörper
  • zgc:110207 Antikörper

Bezeichner auf Proteinebene für MAPKSP1

MAPK scaffold protein 1 , mitogen-activated protein kinase kinase 1 interacting protein 1 , MEK binding partner 1 , late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 , mitogen-activated protein kinase scaffold protein 1 , ragulator complex protein LAMTOR3 , MEK-binding partner 1 , mitogen activated protein, binding protein , mitogen-activated protein kinase kinase 1-interacting protein 1 , MEK partner 1 , Mitogen-activated protein kinase kinase 1-interacting protein 1 , Mitogen-activated protein kinase scaffold protein 1 , putative mitogen-activated protein kinase kinase 1 interacting protein 1

GENE ID SPEZIES
478492 Canis lupus familiaris
8649 Homo sapiens
56692 Mus musculus
533155 Bos taurus
425210 Gallus gallus
362045 Rattus norvegicus
553597 Danio rerio
100190337 Taeniopygia guttata
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