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MAPKSP1 Antikörper (Internal Region)

MAPKSP1 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257364
  • Target Alle MAPKSP1 Antikörper anzeigen
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Bindungsspezifität
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 26
    • 18
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 30
    • 3
    Kaninchen
    Klonalität
    • 30
    • 3
    Polyklonal
    Konjugat
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAPKSP1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 11
    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    LAMTOR3 Antibody detects endogenous levels of total LAMTOR3.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human LAMTOR3, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MAPKSP1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
    Andere Bezeichnung
    LAMTOR3 (MAPKSP1 Produkte)
    Synonyme
    MAPKSP1 antikoerper, MAP2K1IP1 antikoerper, MAPBP antikoerper, MP1 antikoerper, PRO0633 antikoerper, Ragulator3 antikoerper, AW556229 antikoerper, Map2k1ip1 antikoerper, Mapbp antikoerper, Mapksp1 antikoerper, Mp1 antikoerper, mapksp1 antikoerper, zgc:110207 antikoerper, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 antikoerper, LAMTOR3 antikoerper, Lamtor3 antikoerper, lamtor3 antikoerper
    Hintergrund

    Description: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

    Gene: LAMTOR3

    Gen-ID
    8649
    UniProt
    Q9UHA4
    Pathways
    PI3K-Akt Signalweg
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