MAPKSP1 Antikörper (AA 40-90)

Produktnummer ABIN6991975

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAPKSP1 in WB, ELISA, IHC (p) und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MAPKSP1 Antikörper (AA 40-90) (ABIN6991975)

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKSP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-MAPKSP1 Antikörper

Bindungsspezifität: AA 40-90

Spezifität: LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist, this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.

Aufreinigung: LAMTOR3 antibody is affinity chromatography purified via peptide column.

Immunogen: LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LAMTOR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LAMTOR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu MAPKSP1

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Andere Bezeichnung: LAMTOR3

Hintergrund: The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).

Molekulargewicht: Predicted: 14 kDa

Observed: 13 kDa

Gen-ID: 8649

NCBI Accession: NP_068805

UniProt: Q9UHA4

Pathways: PI3K-Akt Signalweg