anti-GADD45A (GADD45A) Antikörper

Bezeichnung:
anti-Growth Arrest and DNA-Damage-Inducible, alpha Antikörper (GADD45A)
Auf www.antikoerper-online.de finden Sie aktuell 84 Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GADD45A Proteine (19) und GADD45A Kits (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 121 GADD45A Produkte verfügbar.
Synonyme:
AA545191, DDIT1, Gadd45, GADD45A, MGC53491, zgc:91795
Alle Antikörper anzeigen Gen GeneID UniProt
GADD45A 13197 P48316
GADD45A 1647 P24522
GADD45A 25112  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-GADD45A (GADD45A) Antikörper

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anti-Mouse (Murine) GADD45A Antikörper:

anti-Human GADD45A Antikörper:

anti-Rat (Rattus) GADD45A Antikörper:

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Am meisten referenzierte anti-GADD45A Antikörper

  1. Human Monoclonal GADD45A Primary Antibody für ELISA, WB - ABIN393701 : Sánchez, Pantoja-Uceda, Prieto, Diercks, Marcaida, Montoya, Campos-Olivas, Blanco: Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für 393701

  2. Human Polyclonal GADD45A Primary Antibody für FACS, WB - ABIN650724 : Li, Morales, Hwang, Wagner, Boothman: DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis. in The Journal of biological chemistry 2008 (PubMed)
    Zeige alle 5 Referenzen für 650724

  3. Human Polyclonal GADD45A Primary Antibody für FACS, WB - ABIN389281 : Al-Romaih, Sadikovic, Yoshimoto, Wang, Zielenska, Squire: Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells. in Neoplasia (New York, N.Y.) 2008 (PubMed)
    Zeige alle 4 Referenzen für 389281

  4. Human Polyclonal GADD45A Primary Antibody für EIA, WB - ABIN453659 : Kearsey, Coates, Prescott, Warbrick, Hall: Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1. in Oncogene 1995 (PubMed)
    Zeige alle 4 Referenzen für 453659

  5. Human Monoclonal GADD45A Primary Antibody für PLA, ELISA - ABIN560584 : Matteucci, Minutolo, Balestrieri, Marino-Merlo, Bramanti, Garaci, Macchi, Mastino: Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis. in Cell death & disease 2011 (PubMed)
    Zeige alle 2 Referenzen für 560584

  6. Human Polyclonal GADD45A Primary Antibody für IF (p), IHC (p) - ABIN685432 : Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. in International journal of nanomedicine 2014 (PubMed)

Weitere Antikörper gegen GADD45A Interaktionspartner

Xenopus laevis Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Interaktionspartner

  1. Gadd45a and Gadd45g (zeige GADD45G Antikörper) regulate neural development and exit from pluripotency in Xenopus.

Zebrafish Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Interaktionspartner

  1. Results provide evidence for a coupled mechanism of 5-methylcytosine (5-meC (zeige CCL28 Antikörper)) demethylation, whereby 5-meC (zeige CCL28 Antikörper) deaminase (AID) deaminates 5-meC (zeige CCL28 Antikörper), followed by thymine base excision by G:T mismatch-specific thymine glycosylase (Mbd4 (zeige MBD4 Antikörper)), promoted by Gadd45.

Pig (Porcine) Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Interaktionspartner

  1. GADD45A gene variants are associated with meat quality in pigs.

Mouse (Murine) Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Interaktionspartner

  1. identifed Gadd45a as a chromatin relaxer in embryonic fibroblasts, which also enhances somatic cell reprogramming efficiency; showed that residue glycine 39 in Gadd45a is essential for interacting with core histones, opening chromatin and enhancing reprogramming. demonstrateed that Gadd45a destabilizes histone-DNA interactions and facilitates binding of Yamanaka factors to their targets for activation

  2. Data show that loss of growth arrest and DNA-damage-inducible 45 alpha protein (Gadd45a) accelerates the onset of BCR-ABL driven leukemia in bone marrow recipient mice.

  3. by forming a complex with MEKK4 (zeige MAP3K4 Antikörper) in skeletal muscle fibers, Gadd45a increases MEKK4 (zeige MAP3K4 Antikörper) protein kinase (zeige CDK7 Antikörper) activity, which is both sufficient to induce skeletal muscle fiber atrophy and required for Gadd45a-mediated skeletal muscle fiber atrophy.

  4. Gadd45a may counteract hepatic fi brosis by regulating the activation of hepatic stellate cells via the inhibition of TGF-beta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) signaling.

  5. These data indicate that genotoxic stress-induced GADD45A expression in HSCs prevents their fatal transformation by directing them into differentiation and thereby clearing them from the system

  6. provide the novel evidence that GADD45A inhibits autophagy via impairing the BECN1 (zeige BECN1 Antikörper)-PIK3C3 (zeige PIK3C3 Antikörper) complex formation

  7. Results suggest the possibility that differential Gadd45a, Gadd45b (zeige GADD45B Antikörper) and Gadd45g (zeige GADD45G Antikörper) expression during development affects neurons, contributing cortical evolution and diversity

  8. GADD45a promoter regulation by a functional genetic variant is associated with acute mechanical lung injury.

  9. In SOD1 (zeige SOD1 Antikörper) and Neurotomized mice the results of this studysuggest LC3 (zeige MAP1LC3A Antikörper), Fn14 (zeige TNFRSF12A Antikörper), Bcl3 (zeige BCL3 Antikörper) and Gadd45a as candidate genes involved in the maintenance of the severe atrophic state.

  10. results for the first time demonstrate that nucleolin (zeige NCL Antikörper)-SUMO at K294R plays a critical role in its nucleus sequestration and gadd45alpha mRNA binding activity.

Human Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Interaktionspartner

  1. The findings indicate that p38alpha (zeige MAPK14 Antikörper) and GADD45alpha are involved in an enhanced vitamin D signaling on TRPV6 (zeige TRPV6 Antikörper) expression.

  2. the enhancement of GADD45A-mediated base excision repair modulated by ATF2 (zeige ATF2 Antikörper) might be a potential protective mechanism of visible red light.

  3. Data show that growth arrest and DNA-damage-inducible 45 alpha protein (Gadd45a) expression is up-regulated in chronic phase myelocytic leukemia, chronic (CML) patient samples but down-regulated in accelerated and blast crisis phase samples.

  4. These data revealed that Riboflavin plus ultraviolet (UV) pathogen reduction technology effectively inhibited proliferation and induced apoptosis of lymphocytes by promoting GADD45alpha expression, which subsequently activates p38 (zeige CRK Antikörper) and JNK (zeige MAPK8 Antikörper) signaling pathways.

  5. data suggest GADD45 proteins play a role in controlling HIV-1 transcription and in regulating HIV-1 latency

  6. Taken together, our results suggest that ROS (zeige ROS1 Antikörper) generation might be a predisposing event in berberine-induced mitochondrial apoptosis in EBV-transformed B cells through the upregulation of XAF1 (zeige XAF1 Antikörper) and GADD45alpha expression by MAPK (zeige MAPK1 Antikörper) and functional p53 (zeige TP53 Antikörper).

  7. Collective results lead us to conclude that GADD45alpha modulates curcumin sensitivity through activation of c-Abl (zeige ABL1 Antikörper) > JNK (zeige MAPK8 Antikörper) signaling in a mismatch repair-dependent manner

  8. BRCA1 may act as an important negative regulator in cell cycle progression and tumorigenesis through regulating the stability of Smad4 (zeige SMAD4 Antikörper); this defines a novel link that connects BRCA1 to TGF-beta1 (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) pathway.

  9. MiR (zeige MLXIP Antikörper)-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45alpha

  10. these data suggest a dual function of GADD45a in oxidative DNA demethylation, to promote directly or indirectly TET1 (zeige TET1 Antikörper) activity and to enhance subsequent 5-formylcytosine/5-carboxylcytosine removal.

GADD45A Antigen-Profil

Beschreibung des Gens

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with GADD45A

  • growth arrest and DNA-damage-inducible, alpha (gadd45a) Antikörper
  • growth arrest and DNA-damage-inducible, alpha, b (gadd45ab) Antikörper
  • growth arrest and DNA-damage-inducible, alpha (GADD45A) Antikörper
  • growth arrest and DNA damage-inducible protein 45 (GADD45) Antikörper
  • growth arrest and DNA-damage-inducible 45 alpha (Gadd45a) Antikörper
  • growth arrest and DNA-damage-inducible, alpha (Gadd45a) Antikörper
  • AA545191 Antikörper
  • DDIT1 Antikörper
  • Gadd45 Antikörper
  • GADD45A Antikörper
  • MGC53491 Antikörper
  • zgc:91795 Antikörper

Bezeichner auf Proteinebene für GADD45A

growth arrest and DNA-damage-inducible, alpha , growth arrest and DNA damage-inducible protein GADD45 alpha , growth arrest and DNA-damage-inducible protein 45 alpha , growth arrest and DNA-damage-inducible protein alpha , growth arrest and DNA damage-inducible protein 45 , Growth arrest and DNA-damage-inducible protein GADD45 alpha , DDIT-1 , DNA damage-inducible transcript 1 protein , DNA-damage inducible transcript 1 , DNA-damage-inducible transcript 1 , Gadd45alpha , growth arrest and DNA-damage-inducible protein GADD45 alpha , DNA damage-inducible transcript-1 , growth arrest and DNA-damage-inducible 45 alpha

GENE ID SPEZIES
379224 Xenopus laevis
431763 Danio rerio
456929 Pan troglodytes
548905 Xenopus (Silurana) tropicalis
693255 Gallus gallus
701054 Macaca mulatta
733669 Sus scrofa
493656 Felis catus
13197 Mus musculus
1647 Homo sapiens
25112 Rattus norvegicus
505463 Bos taurus
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