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GADD45A Produkte

(Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Kategorien

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].

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Ausgewählte GADD45A Kategorien

GADD45A Antikörper

High quality antibodies with extensive validation data.

GADD45A ELISA Kits

Reliable ELISA kits for a wide range of species.

GADD45A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GADD45A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN6140923
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN685432
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN389281
Menge 400 μL
Datenblatt Datenblatt

Empfohlene GADD45A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975062
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956310
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956311
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GADD45A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354677
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354675
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3080304
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GADD45A Produkten

Zheng, Wu, Zhang, Fu, Xu, Lao, Lin, Xu: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." in: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).

Wu, Boonmars, Nagano, Boonjaraspinyo, Srinontong, Ratasuwan, Narong, Nielsen, Maekawa: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).

Shi, Geldenhuys, Sutariya, Bishayee, Patel, Bhatia: "CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells." in: Genes & cancer, Vol. 6, Issue 5-6, pp. 220-30, (2015) (PubMed).

Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

Cheng, Zhao, Zhang, Jiang, Tian, Xiao, Gong: "p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K-Akt pathways." in: The Journal of general virology, Vol. 94, Issue Pt 2, pp. 326-35, (2013) (PubMed).

Matteucci, Minutolo, Balestrieri, Marino-Merlo, Bramanti, Garaci, Macchi, Mastino: "Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis." in: Cell death & disease, Vol. 1, pp. e81, (2011) (PubMed).

Ramachandran, Gopisetty, Gordian, Navarro, Hader, Reis, Schulz, Singal: "Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target." in: Cancer research, Vol. 69, Issue 4, pp. 1527-35, (2009) (PubMed).

Al-Romaih, Sadikovic, Yoshimoto, Wang, Zielenska, Squire: "Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 5, pp. 471-80, (2008) (PubMed).

Synonyme und alternative Namen zu GADD45A

growth arrest and DNA damage inducible alpha L homeolog (gadd45a.L), growth arrest and DNA-damage-inducible, alpha, b (gadd45ab), growth arrest and DNA damage inducible alpha (GADD45A), growth arrest and DNA damage inducible alpha (gadd45a), growth arrest and DNA damage-inducible protein 45 (GADD45), growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), growth arrest and DNA-damage-inducible, alpha (Gadd45a), AA545191, ddit1, Ddit1, DDIT1, gadd45, GADD45, Gadd45, gadd45a, GADD45A, MGC53491, zgc:91795

Bezeichner auf Proteinebene für GADD45A

  • growth arrest and DNA-damage-inducible, alpha
  • growth arrest and DNA damage-inducible protein GADD45 alpha
  • growth arrest and DNA-damage-inducible protein 45 alpha
  • growth arrest and DNA-damage-inducible protein alpha
  • growth arrest and DNA damage-inducible protein 45
  • Growth arrest and DNA-damage-inducible protein GADD45 alpha
  • DDIT-1
  • DNA damage-inducible transcript 1 protein
  • DNA-damage inducible transcript 1
  • DNA-damage-inducible transcript 1
  • Gadd45alpha
  • growth arrest and DNA-damage-inducible protein GADD45 alpha
  • DNA damage-inducible transcript-1
  • growth arrest and DNA-damage-inducible 45 alpha
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