anti-Schaf Thyroid Hormone Receptor, beta Antikörper für Western Blotting

Recommended Thyroid Hormone Receptor, beta Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Thyroid Hormone Receptor, beta (THRB) Antikörper
  • LOC734147
  • thrb
  • NR1A2
  • THRB
  • C-erba-beta
  • ERBA2
  • Nr1a2
  • RATT3REC
  • T3rec
  • TRbeta
  • T3R[b]
  • T3Rbeta
  • Thrb1
  • Thrb2
  • c-erbAbeta
  • TR-beta
  • TR[b]1
  • fj24f03
  • trb
  • wu:fj24f03
  • C-ERBA-2
  • C-ERBA-BETA
  • GRTH
  • PRTH
  • THR1
  • THRB1
  • THRB2
  • THR
  • TRbeta1
  • CTR BETA 2
  • TR-BETA
  • thyroid hormone receptor, beta
  • thyroid hormone receptor beta
  • thrb
  • THRB
  • Thrb
Epitop
N-Term
24
22
5
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Schaf
107
59
58
12
10
8
7
7
6
6
4
3
3
1
1
1
Wirt
Kaninchen
88
31
9
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
87
53
30
16
13
6
5
4
3
2
2
2
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN2780344
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.236848 ABIN2780345 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
3.236848 ABIN2776374 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN468318 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Thyroid Hormone Receptor, beta (THRB) Antikörper
Epitop N-Term
(24), (22), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Schaf
(107), (59), (58), (12), (10), (8), (7), (7), (6), (6), (4), (3), (3), (1), (1), (1)
Wirt Kaninchen
(88), (31), (9)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
(87), (53), (30), (16), (13), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985076.
Sequenz MTPNSMTENG LTAWDKPKHC PDREHDWKLV GMSEACLHRK SHSERRSTLK
Homologie Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%
Produktmerkmale This is a rabbit polyclonal antibody against THRB. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human THRB

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung THRB (THRB Antibody Abstract)
Hintergrund THRB is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several transcript variants have been observed for this gene, but the full-length nature of only one has been determined so far. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Alias Symbols: ERBA-BETA, ERBA2, GRTH, MGC126109, MGC126110, NR1A2, THR1, THRB1, THRB2, PRTH, C-ERBA-2, C-ERBA-BETA
Protein Interaction Partner: NSD1, NCOA1, RANBP9, NCOR1, RXRA, THRB, MMS19, ADAT3, NCOA2, C1D, NCOA3, ATF2, ANP32A, SUMO1, SUMO2, ROBO4, MED21, HMGN3, EIF3I, NRIP1, RXRG, RXRB, CAMK2B, TBL1XR1, NCOR2, HDAC3, SMC1A, XRCC5, TBL1X, PRKDC, LIG3, HSPA4, GPS2, XRCC6, PARP1, LRIF1, SRC, PSM
Protein Size: 461
Molekulargewicht 53 kDa
Gen-ID 7068
NCBI Accession NM_000461, NP_000452
UniProt P10828
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 461 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Arnaud-Lopez, Usala, Ceresini, Mitchell, Pilia, Piras, Sestu, Maschio, Busonero, Albai, Dei, Lai, Mulas, Crisponi, Tanaka, Bandinelli, Guralnik, Loi, Balaci, Sole, Prinzis, Mariotti, Shuldiner, Cao, Schlessinger, Uda, Abecasis, Nagaraja, Sanna, Naitza: "Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1270-80, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibody (ABIN2780344) WB Suggested Anti-THRB Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
 image for anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibody (ABIN2780344) Application: ChIP
Sample type
: mouse liver tissue
Chromatin Us...
 image for anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibody (ABIN2780344) anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibody (Image 3)