anti-NFKBIA (NFKBIA) Antikörper

Bezeichnung:
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha Antikörper (NFKBIA)
Auf www.antikoerper-online.de finden Sie aktuell 511 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antikörper von 35 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NFKBIA Kits (37) und NFKBIA Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 577 NFKBIA Produkte verfügbar.
Synonyme:
AI462015, ECI-6/IKBA, IKBA, MAD-3, NFKBI, RL/IF-1

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Am meisten referenzierte anti-NFKBIA Antikörper

  1. Human Polyclonal NFKBIA Primary Antibody für EIA, WB - ABIN357736 : Miskolci, Castro-Alcaraz, Nguyen, Vancura, Davidson, Vancurova: Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils. in Archives of biochemistry and biophysics 2003 (PubMed)
    Zeige alle 5 Referenzen für 357736

  2. Human Polyclonal NFKBIA Primary Antibody für DB - ABIN650851 : Wu, Walenkamp, Lankester, Bidlingmaier, Wit, De Luca: Growth hormone and insulin-like growth factor I insensitivity of fibroblasts isolated from a patient with an I{kappa}B{alpha} mutation. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)
    Zeige alle 2 Referenzen für 650851

  3. Human Polyclonal NFKBIA Primary Antibody für FACS, IF - ABIN652417 : Tojima, Fujimoto, Delhase, Chen, Hatakeyama, Nakayama, Kaneko, Nimura, Motoyama, Ikeda, Karin, Nakanishi: NAK is an IkappaB kinase-activating kinase. in Nature 2000 (PubMed)
    Zeige alle 2 Referenzen für 652417

  4. Human Polyclonal NFKBIA Primary Antibody für IF (p), IHC (p) - ABIN741360 : Fu, Shi, Song, Xia, Su, Liu, Song, Song: Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling. in Environmental toxicology and pharmacology 2016 (PubMed)

  5. Human Polyclonal NFKBIA Primary Antibody für WB - ABIN389074 : Place, Haspeslagh, Giardina: Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation. in Journal of cellular physiology 2003 (PubMed)

  6. Cow (Bovine) Polyclonal NFKBIA Primary Antibody für WB - ABIN2792229 : Truhlar, Mathes, Cervantes, Ghosh, Komives: Pre-folding IkappaBalpha alters control of NF-kappaB signaling. in Journal of molecular biology 2008 (PubMed)

  7. Human Polyclonal NFKBIA Primary Antibody für IHC, ELISA - ABIN1531661 : Haskill, Beg, Tompkins, Morris, Yurochko, Sampson-Johannes, Mondal, Ralph, Baldwin: Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. in Cell 1991 (PubMed)

  8. Human Polyclonal NFKBIA Primary Antibody für IHC, WB - ABIN2792665 : Janssen, van Wengen, Hoeve, ten Dam, van der Burg, van Dongen, van de Vosse, van Tol, Bredius, Ottenhoff, Weemaes, van Dissel, Lankester: The same IkappaBalpha mutation in two related individuals leads to completely different clinical syndromes. in The Journal of experimental medicine 2004 (PubMed)

Weitere Antikörper gegen NFKBIA Interaktionspartner

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Interaktionspartner

  1. Mechanistic analysis suggest that USP12 may be required for the activation of NFkappaB pathway as knockdown of USP12 reduced the inhibitory phosphorylation of IkappaBalpha, a well characterized inhibitor of NFkappaB nuclear translocation.

  2. SM22alpha (zeige TAGLN Antikörper) is a phosphorylation-regulated (zeige PHAX Antikörper) suppressor of IKK (zeige CHUK Antikörper)-IkappaBalpha-NF-kappaB (zeige NFKB1 Antikörper) signaling cascades.

  3. We found potential links between the alterations in expression of Tsc22d3 (zeige TSC22D3 Antikörper), Nfkbia and Pdyn (zeige PDYN Antikörper), and different aspects of susceptibility to stress.

  4. Specific and constitutive deletion of the inhibitor of NF-kappaB (zeige NFKB1 Antikörper) (IkappaBalpha) in eosinophils in vivo reduced apoptosis during helminth infection

  5. GRK6 (zeige GRK6 Antikörper) directly phosphorylates Nfkbia at Ser32/Ser36. Knockdown of GRK6 (zeige GRK6 Antikörper) suppresses TNF-alpha (zeige TNF Antikörper)-induced NF-kappaappaB signaling.

  6. Results demonstrate novel roles of TNFRII (zeige TNFRSF1B Antikörper) in the regulation of Abeta (zeige APP Antikörper) production, suggesting a potential therapeutic strategy for Alzheimer's disease by up-regulating TNFRII (zeige TNFRSF1B Antikörper) levels and elevating phosphorylated IkappaBalpha by SUMOylation.

  7. Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IkappaBalpha.

  8. Dengue virus protease interacts with both NF-kappaB inhibitor alpha (IkappaBalpha) and NF-kappaB (zeige NFKB1 Antikörper) inhibitor beta (IkappaBbeta (zeige NFKBIB Antikörper)), cleaving them in a mouse hemorrhage model.

  9. The results indicate that following heat shock treatment, HuR (zeige ELAVL1 Antikörper) translocates from the nucleus to the cytoplasm, forming stress granules and regulating the translation of IkBalpha mRNA without affecting the half-life.

  10. Data show that inhibition of nuclear factor-kappaB (NF-kappaB (zeige NFKB1 Antikörper)) in IKBM protects the mice from monocrotaline (MCT (zeige MCAT Antikörper))-induced pulmonary arterial hypertension and right ventricular hypertrophy.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Interaktionspartner

  1. The results showed that NFKB1 (zeige NFKB1 Antikörper) and NFKBIA single-nucleotide polymorphisms and gastric cancer are related and that the combined effects of polymorphisms in two genes and the NFKBIA gene monomer increased the risk of gastric cancer, and it was found that in different types of gastric cancer (the cardia and non-cardia cancer), susceptible polymorphism sites and combined effects are different.

  2. Double phosphorylation-induced structural changes in the signal-receiving domain of IkappaBalpha in complex with NF-kappaB (zeige NFKB1 Antikörper) have been described.

  3. Here, the authors report amide hydrogen/deuterium exchange data that reveal long-range allosteric changes in the NFkappaB (zeige NFKB1 Antikörper) (RelA (zeige NFkBP65 Antikörper)-p50 (zeige CD40 Antikörper)) heterodimer induced by DNA or IkappaBalpha binding.

  4. Sam68 (zeige KHDRBS1 Antikörper) is essential for DNA damage-induced NF-kappaB (zeige NFKB1 Antikörper) activation and colon tumorigenesis.

  5. Specifically, BCA2 (zeige RNF115 Antikörper) serves as an E3 SUMO ligase in the SUMOylation of IkappaBalpha, which in turn enhances the sequestration of NF-kappaB (zeige NFKB1 Antikörper) components in the cytoplasm. Since HIV-1 utilizes NF-kappaB (zeige NFKB1 Antikörper) to promote proviral transcription, the BCA2 (zeige RNF115 Antikörper)-mediated inhibition of NF-kappaB (zeige NFKB1 Antikörper) significantly decreases the transcriptional activity of HIV-1.

  6. This study found that NFKBIA mRNAs was significantly expressed in normal tissues compared with glioma specimens.

  7. Findings indicate the prognostic value of NFKB inhibitor alpha (NFKBIA) in lower-grade gliomas (LGGs).

  8. W346 effectively inhibited tumor necrosis factor (TNF-a (zeige TNF Antikörper))-induced NF-kappaB (zeige NFKB1 Antikörper) activation by suppressing IKK (zeige CHUK Antikörper) phosphorylation, inhibiting IkB (zeige NFKBIB Antikörper)-a degradation, and restraining the accumulation of NF-kappaB (zeige NFKB1 Antikörper) subunit p65 (zeige GORASP1 Antikörper) nuclear translocation. W346 also affected NF-kappaB (zeige NFKB1 Antikörper)-regulated downstream products involved in cycle arrest and apoptosis.

  9. treating cells with SZC014 resulted in a decrease in phosphorylation of IkBa and NF-kappaB (zeige NFKB1 Antikörper)/p65 (zeige GORASP1 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper)/p65 (zeige GORASP1 Antikörper) nuclear translocation. The cytotoxic activities of seven OA derivatives were generally stronger than that of OA, among which, SZC014 possessed the most potent anticancer activity in SGC7901 cells and would be a promising chemotherapic agent for the treatment of gastric cancer

  10. Network analysis identified NFKBIA as pathogenic gene in childhood asthma.

Cow (Bovine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Interaktionspartner

  1. IkappaB-alpha protein was stabilized by COMMD1 (zeige COMMD1 Antikörper), which attenuated NF-kappaB (zeige NFKB1 Antikörper) signaling during Toll (zeige TLR4 Antikörper)-like receptor ligand and tumor necrosis factor alpha (zeige TNF Antikörper) treatment and enhanced HIV-1 latency in latently HIV-1-infected cells.

  2. NFKBIA has a role as a marker of NF-kappaB (zeige NFKB1 Antikörper)/p65 (zeige SYT1 Antikörper) activation in the early embryo.

  3. NF-kappaB (zeige NFKB1 Antikörper) has a role in increasing PDGF-B (zeige PDGFB Antikörper) transcription

  4. AIP1 (zeige PDCD6IP Antikörper) is a novel transducer in TNF (zeige TNF Antikörper)-induced TRAF2 (zeige TRAF2 Antikörper)-dependent activation of ASK1 (zeige MAP3K5 Antikörper) that mediates a balance between JNK (zeige MAPK8 Antikörper) versus NF-kappaB (zeige NFKB1 Antikörper) signaling

  5. GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.

NFKBIA Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Alternative names and synonyms associated with NFKBIA

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (LOC100220015) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (LOC100357341) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha (Nfkbia) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Nfkbia) Antikörper
  • AI462015 Antikörper
  • ECI-6/IKBA Antikörper
  • IKBA Antikörper
  • MAD-3 Antikörper
  • NFKBI Antikörper
  • RL/IF-1 Antikörper

Bezeichner auf Proteinebene für NFKBIA

NF-kappa-B inhibitor alpha , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha , I(Kappa)B(alpha) , I-kappa-B-alpha , I-kappaBalpha , ikB-alpha , ikappaBalpha , nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha , nuclear factor of kappa light polyp gene enhancer in B-cell 1 , IkappaBalpha , major histocompatibility complex enhancer-binding protein MAD3 , nuclear factor of kappa light chain gene enhancer in B-cells , ECI-6 , I kappa B-alpha , IKB-alpha , NF-kappaB inhibitor alpha , REL-associated protein pp40 , Rel-associated pp40 , IkappaB alpha , Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha , Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha

GENE ID SPEZIES
780520 Ovis aries
100220015 Taeniopygia guttata
100357341 Oryctolagus cuniculus
18035 Mus musculus
4792 Homo sapiens
406188 Sus scrofa
396093 Gallus gallus
480291 Canis lupus familiaris
282291 Bos taurus
25493 Rattus norvegicus
Ausgewählte Anbieter für anti-NFKBIA (NFKBIA) Antikörper
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