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Rat (Rattus) HDAC1 ELISA Kit für Sandwich ELISA - ABIN432608
Bang, Ambavade, Jagdale, Adkar, Waghmare, Ambavade: Lacosamide reduces HDAC levels in the brain and improves memory: Potential for treatment of Alzheimer's disease. in Pharmacology, biochemistry, and behavior 2015
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Mechanical stimulation orchestrates the osteogenic differentiation of human bone marrow stromal cells by regulating HDAC1.
Co-regulation of H3K9ac by HDAC1 and HDAC3 (zeige HDAC3 ELISA Kits) is important to both embryonic brain development and neuro-differentiation.
Treatment of the haplotype Npr1 (zeige NPR1 ELISA Kits)(+/-) mice with histone deacetylase inhibitors significantly lowered blood pressure and reduced the renal inflammation and fibrosis involving the interactive roles of HDAC1/2, NF-kappaB (zeige NFKB1 ELISA Kits) (p65 (zeige NFkBP65 ELISA Kits)), and STAT1 (zeige STAT1 ELISA Kits).
Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (zeige CREBBP ELISA Kits) and HDAC1-HDAC2 has been described.
Here, we use transgenic lines to define the in vivo relevance of HDAC1 and identify calcineurin-dependent serine dephosphorylation as the signal modulating the neurotoxic role of HDAC1 in response to neurotoxic stimuli.
In line with the acetyltransferase activity of p300 (zeige NOTCH1 ELISA Kits), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (zeige HDAC3 ELISA Kits) activity maintains PTGES1 expression by recruiting p300 (zeige NOTCH1 ELISA Kits) to its gene
provide new insight into the upstream regulation of Sap90/Psd95 (zeige DLG4 ELISA Kits)-associated protein 3 (zeige HSPB3 ELISA Kits) and establish the essential role of striatal Hdac1, Hdac2 (zeige HDAC2 ELISA Kits) and MeCP2 for suppression of repetitive behaviors
Taken together, Fam60a is an essential core subunit of a variant Sin3a-Hdac (zeige HDAC3 ELISA Kits) complex in embryonic stem cells that is required to promote rapid proliferation and prevent unscheduled differentiation.
HDAC1 may be an essential epigenetic regulator of the transition from progenitor cells to terminally differentiated photoreceptors
Knockdown of HDAC1 recovered Bdnf (zeige BDNF ELISA Kits) and Pvalb (zeige PVALB ELISA Kits) gene transcription and also prevented the decrease of inhibitory synapses accompanying whisker deprivation
These results reveal the presence of an MSI1 (zeige MSI1 ELISA Kits)-HDA19 complex that fine-tunes abscissic acid signaling in Arabidopsis.
HDC1 is a ubiquitously expressed nuclear protein that interacts with at least two deacetylases (HDA6 (zeige HDAC6 ELISA Kits) and HDA19), promotes histone deacetylation, and attenuates derepression of genes under water stress.
HDA19 and HSL1 may act together to repress seed maturation gene expression during germination. HDA19 and HSL1 may play a vital role during embryogenesis.
findings show that AP2 represses its target genes by physically recruiting the co-repressor TOPLESS and the histone deacetylase HDA19
HDA6 (zeige HDAC6 ELISA Kits) and HDA19 may play a redundant role in modulating seed germination and salt stress response, as well as ABA- and salt stress-induced gene expression in Arabidopsis.[HDA19]
Data suggest that AtHD1 is a nuclear protein (zeige HEMGN ELISA Kits) and possesses histone deacetylase activities responsible for global transcriptional regulation important to plant growth and development.
These results suggest that acetylation of specific histone Lys (zeige LYZ ELISA Kits) residues, regulated by GCN5, TAF1, and HD1, is required for light-regulated gene expression.
These results suggest that during germination in Arabidopsis, HDA6 (zeige HDAC6 ELISA Kits) and HDA19 redundantly regulate the repression of embryonic properties directly or indirectly via repression of embryo-specific gene function.
aken together, these results reveal that inactivation of Rpd3 independently regulates JNK (zeige MAPK8 ELISA Kits) and Yki (zeige YAP1 ELISA Kits) activities and that both Hippo and JNK (zeige MAPK8 ELISA Kits) signaling pathways contribute to Rpd3 RNAi-induced apoptosis.
Rpd3 accumulates in the nucleolus in the early stage of starvation, upregulates rRNA synthesis, maintains the polysome amount for translation, and finally increases stress tolerance proteins, such as autophagy-related proteins, to acquire starvation stress resistance.
Hdac1/Rpd3 functions together with self-renewal transcriptional repressors to maintain the erm (zeige MSN ELISA Kits) immature intermediate neural progenitors enhancer in an inactive but poised state in neuroblasts.
This study tested the longevity effects of RPD3 on multiple nutrient levels.
Rpd3 deacetylase in the heart plays a significant role in cardiac function and longevity to systemically modulate the fly's response to the environment
the Atro-Rpd3 complex plays a conserved role to function as a Ci(R) corepressor.
Study shows that Fru (zeige ZBTB22 ELISA Kits) forms a complex with the transcriptional cofactor Bonus (Bon), which, in turn, recruits either of two chromatin regulators, Histone deacetylase 1 (HDAC1), which masculinizes individual sexually dimorphic neurons, or Heterochromatin protein 1a (HP1a (zeige CBX5 ELISA Kits)), which demasculinizes them.
The dose of Rpd3 is critical for normal long-term memory.
Work suggests that Drosophila telomere structure is epigenetically regulated by the histone deacetylase Rpd3.
Our study suggests a specific function for the general chromatin remodeling factor (zeige ASH1L ELISA Kits) Rpd3 in regulating dendrite targeting in neurons, largely through the postmitotic action of the Pros transcription factor.
Histone deacetylases (HDACs) inhibitor MGCD0103 (MGCD) induces apoptosis by up-regulating p53 (zeige TP53 ELISA Kits) in CNE2 nasopharyngeal carcinoma (NPC (zeige NPC1 ELISA Kits)) cells.
Our findings suggest that up-regulation of UVRAG by HDAC1 inhibition potentiates DNA-damage-mediated cell death in colorectal cancer cells
The findings suggest that OGT (zeige OGT ELISA Kits) promotes the O-GlcNAc (zeige OGT ELISA Kits) modification of HDAC1 in the development of progression hepatocellular carcinoma.
HDAC1 promoted migration and invasion of gallbladder tumor cells by binding with TCF12 (zeige TCF12 ELISA Kits) to promote epithelial mesenchymal transformation.
HDAC1 depletion-induced p53 (zeige TP53 ELISA Kits) expression alters cardiac-derived mesenchymal stromal cell fate decisions.
These results are the first evidence that the inhibition of HDAC1 by (S)-2 downregulates CIP2A (zeige KIAA1524 ELISA Kits) transcription
data showed that HDAC1 can trigger the proliferation and migration of breast cancer cells via activation of Snail (zeige SNAI1 ELISA Kits)/IL-8 (zeige IL8 ELISA Kits) signals
Mechanical stimulation orchestrates the osteogenic differentiation of human bone marrow stromal cells by regulating HDAC1
High HDAC1 expression is associated with Multidrug Resistance in breast and cervical cancer.
these results suggest that HDAC1 and HDAC6 may play a role in clear cell renal cell carcinoma biology
The effect of p53 (zeige TP53 ELISA Kits) expression on the development of cloned embryos, and its interaction with HDAC1 and DNMT3A (zeige DNMT3A ELISA Kits) are reported.
The results suggest that HDAC1 knock-down in oocytes did not influence the rates of maturation or cleavage of parthenogenetic embryos.
results indicate that HDAC1 plays an important role in otic vesicle formation.
HDAC (zeige HDAC3 ELISA Kits) activity is necessary for control of cell proliferation and migration of posterior lateral line primordium and hair cell differentiation during early stages of its development in zebrafish.
This study reveals distinct functional and temporal requirements for zebrafish hdac1 during neural crest-derived craniofacial and peripheral neuron development.
Hdac1 is required for expression of erm and fgf20a in rhombomeres; Hdac1-dependent expression of these two genes is attenuated in rhombomere boundary regions by Notch (zeige NOTCH1 ELISA Kits) signalling activity
HDAC1 is required for pancreatic epithelial proliferation in development and cancer.
Data indicate a novel role for Hdac1 as a positive regulator of gene transcription during development of the vertebrate CNS.
Findings suggest that Mta3 (zeige MTA1 ELISA Kits)-NuRD complex, inclding component HDAC1, is essential for the initiation of primitive hematopoiesis.
hdac1 is an essential component of the transcriptional silencing machinery that supports the formation and subsequent differentiation of neuronal precursors.
hdac1 is required for the normal formation of craniofacial cartilage and pectoral fins.
in vivo role of HDAC1 in regulating cell cycle progression is region-specific, as HDAC1 promotes cell cycle exit in the retina
Data show that proto-oncogene transcription factor Ets1 regulates neural crest development through histone deacetylase 1 HDAC1) to down-regulate bone morphogenetic protein (BMP) signaling output and reduce id3 protein expression.
Specific knockdown of HDAC1 by a morpholino (HDAC1-MO) decreased the number of BrdU- and BLBP-labeled cells and increased the acetylation level of histone H4 at lysine 12.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
, histone deacetylase 1
, histone deacetylase 1-B
, Rpd3 histone deacetylase
, histone Deacetylase-1
, histone deacetylase
, histone deacetylase 1 (HDAC1)
, reduced potassium dependency 3
, suppressor of variegation 326
, reduced potassium dependency, yeast homolog-like 1
, histone deacetylase 1 b