anti-Schwein TUBA1B Antikörper für Western Blotting

Recommended TUBA1B Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tubulin, alpha 1B (TUBA1B) Antikörper
  • K-ALPHA-1
  • k-alpha-1
  • tuba
  • tuba1
  • Tuba2
  • RGD1565476
  • TUBA3
  • TUBAT
  • similar to alpha tubulin
  • alpha tubulin
  • tubulin, alpha 1b
  • tubulin, alpha 1B
  • tubulin, alpha 8
  • RGD1560000
  • LOC100009327
  • TUBA1B
  • tuba1b
  • Tuba1b
  • TUBA8
Epitop
N-Term
8
5
5
4
3
2
2
2
1
1
Reaktivität
Human, Schwein, Maus
43
16
13
8
5
5
3
3
2
2
2
2
1
1
1
1
1
Wirt
Maus
28
22
2
Klonalität
Monoklonal
Konjugat
Dieser TUBA1B Antikörper ist unkonjugiert
3
2
1
Applikation
Western Blotting (WB)
49
25
23
17
14
8
7
7
5
2
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Dieses Produkt umsonst

Schicken Sie uns Ihren Validierungsvorschlag. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN93896
231,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN238516 WB Mouse IgM Anmelden zum Anzeigen TU-02 3
1 ABIN5552615 IHC (p) IP WB Rabbit AA 426-450, C-Term Anmelden zum Anzeigen Polyclonal

anti-TUBA1B Antikörper für Western Blotting mit den meisten Publikationen

Ähnliche anti-TUBA1B Antikörper

Applikation / Reaktivität Human Schwein Maus
Western Blotting (WB) 42 Antikörper 3 Antikörper 16 Antikörper
Radioimmunoassay (RIA) 1 Antikörper 1 Antikörper
Immunoprecipitation (IP) 2 Antikörper 2 Antikörper 1 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antikörper 9 Antikörper 1 Antikörper
Immunohistochemistry (IHC) 14 Antikörper 7 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antikörper 2 Antikörper

General

Antigen Tubulin, alpha 1B (TUBA1B) Antikörper
Epitop N-Term
(8), (5), (5), (4), (3), (2), (2), (2), (1), (1)
Reaktivität Human, Schwein, Maus
(43), (16), (13), (8), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Maus
(28), (22), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser TUBA1B Antikörper ist unkonjugiert
(3), (2), (1)
Applikation Western Blotting (WB)
(49), (25), (23), (17), (14), (8), (7), (7), (5), (2), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TUBA1B Antikörper

Target Details TUBA1B Anwendungsinformationen Handhabung ProductDetails: References for anti-TUBA1B antibody (ABIN93896) Bilder
Spezifität The antibody TU-02 recognizes an epitope on N-terminal structural domain of alpha-tubulin in various species.
Reinigung Purified from ascites by precipitation methods.
Reinheit > 95 % (by SDS-PAGE)
Immunogen microtubule proteins from porcine brain
Klon TU-02
Isotyp IgM

Target Details TUBA1B

Produktdetails anti-TUBA1B Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-TUBA1B antibody (ABIN93896) Bilder zurück nach oben
Antigen
Andere Bezeichnung TUBA1B (TUBA1B Antibody Abstract)
Hintergrund The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). The microtubules consist of 13 protofilaments and have an outer diameter 25 nm. Microtubules have their intrinsic polarity, highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening –, this phenomenon is called dynamic instability of microtubules. On a practical level, microtubules can easily be stabilized by the addition of non-hydrolysable analogues of GTP (eg. GMPPCP) or more commonly by anti-cancer drugs such as Taxol. Taxol stabilizes microtubules at room temperature for many hours. Using limited proteolysis by enzymes both tubulin subunits can be divided into N-terminal and C-terminal structural domains.The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants - tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in C-terminal structural domain.
Forschungsgebiet Cytoskeleton
Pathways Microtubule Dynamics, M Phase

Anwendungsinformationen

Produktdetails anti-TUBA1B Antikörper Target Details TUBA1B Handhabung ProductDetails: References for anti-TUBA1B antibody (ABIN93896) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TUBA1B Antikörper Target Details TUBA1B Anwendungsinformationen ProductDetails: References for anti-TUBA1B antibody (ABIN93896) Bilder zurück nach oben
Konzentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handhabung Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

ProductDetails: References for anti-TUBA1B antibody (ABIN93896)

Produktdetails anti-TUBA1B Antikörper Target Details TUBA1B Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Smertenko, Blume, Viklický, Dráber: "Exposure of tubulin structural domains in Nicotiana tabacum microtubules probed by monoclonal antibodies." in: European journal of cell biology, Vol. 72, Issue 2, pp. 104-12, 1997

Dráber, Dráberová, Linhartová, Viklický: "Differences in the exposure of C- and N-terminal tubulin domains in cytoplasmic microtubules detected with domain-specific monoclonal antibodies." in: Journal of cell science, Vol. 92 ( Pt 3), pp. 519-28, 1990

Dráber, Dráberová, Zicconi, Sellitto, Viklický, Cappuccinelli: "Heterogeneity of microtubules recognized by monoclonal antibodies to alpha-tubulin." in: European journal of cell biology, Vol. 41, Issue 1, pp. 82-8, 1987

Bilder

Produktdetails anti-TUBA1B Antikörper Target Details TUBA1B Anwendungsinformationen Handhabung ProductDetails: References for anti-TUBA1B antibody (ABIN93896) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-TUBA1B Antikörper (Tubulin, alpha 1B) (N-Term) (ABIN93896) Western blot of human Jurkat T cell line