anti-Filamin A (FLNA) Antikörper

Bezeichnung:
anti-Filamin A, alpha Antikörper (FLNA)
Auf www.antikoerper-online.de finden Sie aktuell 155 Filamin A, alpha (FLNA) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Filamin A Kits (32) und Filamin A Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 196 Filamin A Produkte verfügbar.
Synonyme:
ABP-280, ABPX, cb967, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, Fln1, flna, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd18g06, wu:fd49a06, XLVD, XMVD

Meistgesuchte Reaktivitäten zu anti-Filamin A (FLNA) Antikörper

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anti-Human Filamin A Antikörper:

anti-Rat (Rattus) Filamin A Antikörper:

anti-Mouse (Murine) Filamin A Antikörper:

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Am meisten referenzierte anti-Filamin A Antikörper

  1. Human Monoclonal Filamin A Primary Antibody für IHC (p), PLA - ABIN560922 : Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ... in Nature genetics 2010 (PubMed)
    Zeige alle 7 Referenzen für 560922

  2. Human Monoclonal Filamin A Primary Antibody für WB - ABIN1882243 : Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. in The Journal of cell biology 1990 (PubMed)
    Zeige alle 6 Referenzen für 1882243

  3. Human Polyclonal Filamin A Primary Antibody für ICC, IF - ABIN188803 : Thoms, Loveridge, Simpson, Clipson, Reinhardt, Dunlop, Stark: Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination. in Cancer research 2010 (PubMed)
    Zeige alle 2 Referenzen für 188803

  4. Human Polyclonal Filamin A Primary Antibody für FACS, IF - ABIN392193 : Maceyka, Alvarez, Milstien, Spiegel: Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration. in Molecular and cellular biology 2008 (PubMed)

Weitere Antikörper gegen Filamin A Interaktionspartner

Zebrafish Filamin A, alpha (FLNA) Interaktionspartner

  1. Knockdown of filamin A or vimentin (zeige VIM Antikörper) in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.

Fruit Fly (Drosophila melanogaster) Filamin A, alpha (FLNA) Interaktionspartner

  1. Here we show using Drosophila indirect flight mus (zeige KPTN Antikörper)cle that t (zeige FLNC Antikörper)he filamin ortholog Cheerio in conjunction with the giant elastic protein titin plays a crucial role in keeping thin filaments stably anchored at the Z-disc. We identify the filamin domains required for interaction with the (zeige TTN Antikörper) titin ortholog Sallimus, and we demonstrate a genetic interaction of filamin with titin and actin.

  2. study identifies Cher as a new target of JNK (zeige MAPK8 Antikörper) signaling that links cytoskeleton dynamics to tumor progression.

  3. Data indicate that during embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells.

  4. Filamin is required for ovarian follicle cell motility during oogenesis.

Human Filamin A, alpha (FLNA) Interaktionspartner

  1. These results provide new insights into the regulation of SK2 (zeige KCNN2 Antikörper) channel trafficking by the cytoskeletal proteins FLNA and alpha-actinin2, involving distinct recycling pathways

  2. Respiratory failure secondary to progressive obstructive lung disease during infancy may be the presenting phenotype of FLNA-associated periventricular nodular heterotopia.

  3. The actin regulator FLNA interacts with the endoplasmic reticulum stress kinase PERK and this interaction is required for the efficient formation of ER-plasma membrane contact sites.

  4. CCR2B (zeige CCR2 Antikörper) and beta2AR (zeige ADRB2 Antikörper) signals to FLNa to stimulate its endocytosis and recycling to the plasma membrane.

  5. In humans, mutations in the actin-binding protein (zeige KPTN Antikörper) Filamin-C (zeige FLNC Antikörper) result in myopathies, but the underlying molecular function is not well understood. Here we show using Drosophila indirect flight muscle that the filamin ortholog Cheerio in conjunction with the giant elastic protein titin (zeige TTN Antikörper) plays a crucial role in keeping thin filaments stably anchored at the Z-disc

  6. Case Report: Reduced binding of mutant FLNa to beta3 and the facilitated recruitment of talin by beta3 on platelet stimulation, explaining the increased alphaIIbbeta3 activation and the ensuing gain-of-platelet functions.

  7. results reveal an unusual structural and thermodynamic basis for the P2204L-induced dysfunction of filamin and frontometaphyseal dysplasia disease.

  8. Mechanistic analysis revealed that FLNA suppresses pol III gene transcription by confining the recruitment of the RNA pol III transcription machinery at the promoters of the genes that are sensitive to the alteration of FLNA expression.

  9. FlnA more strongly binds RhoA (zeige RHOA Antikörper), although both filamins overlap with RhoA (zeige RHOA Antikörper) expression in the cell cytoplasm. FlnA promotes RhoA (zeige RHOA Antikörper) activation whereas FlnB (zeige FLNB Antikörper) indirectly inhibits this pathway. Moreover, FlnA loss leads to diminished expression of b1-integrin, whereas FlnB (zeige FLNB Antikörper) loss promotes integrin expression

  10. FLNA can function as a modulator of chemosensitivity to docetaxel in triple-negative breast cancer (TNBC) cells through regulation of the MAPK/ERK (zeige MAPK1 Antikörper) pathway both in vitro and in vivo. FLNA may serve as a novel therapeutic target for improvement of chemotherapy efficacy in TNBC.

Pig (Porcine) Filamin A, alpha (FLNA) Interaktionspartner

  1. filamin reduces ENaC (zeige SCNN1A Antikörper) channel function through direct interaction on the cell surface

Mouse (Murine) Filamin A, alpha (FLNA) Interaktionspartner

  1. FlnA binding to PACSIN2 (zeige PACSIN2 Antikörper) F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

  2. FlnA is a critical upstream element of the signaling cascade underlying the myogenic tone.

  3. Bones lacking filamin A are protected from estrogen-mediated post-menopausal osteoporosis

  4. findings suggest a model in which filamin A local translation following axon injury controls localized HDAC5 (zeige HDAC5 Antikörper) activity to promote axon regeneration.

  5. Deletion of filamin A in endothelial cells aggravated myocardial infarction-induced left ventricle dysfunction and cardiac failure as a result of defective endothelial response

  6. A new signaling set, phosphatidic acid-S6K1-FLNA-actin, sheds light into the morphogenic pathway of cytoskeletal structures that are crucial for adhesion and cell locomotion during inflammation and metastasis.

  7. Filamin-A is associated with neutrophil uropod retraction.

  8. Analysis of editing in the filamin A encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA editing is mainly achieved by ADAR2 (zeige ADARB1 Antikörper) but that in some cases ADAR1 (zeige ADAR Antikörper) can efficiently compensate for ADAR2 (zeige ADARB1 Antikörper).

  9. Filamin a, b-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeleton.

  10. a major function of FLNa in modulating ion channel abundance and membrane trafficking in neurons, thereby shaping their biophysical properties and function.

Filamin A (FLNA) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Filamin A (FLNA)

  • filamin A, alpha (actin binding protein 280) (flna) Antikörper
  • filamin A, alpha (FLNA) Antikörper
  • filamin B, like (flnbl) Antikörper
  • filamin A, alpha (flna) Antikörper
  • cheerio (cher) Antikörper
  • filamin A, alpha (Flna) Antikörper
  • filamin, alpha (Flna) Antikörper
  • ABP-280 Antikörper
  • ABPX Antikörper
  • cb967 Antikörper
  • CG3937 Antikörper
  • Cher Antikörper
  • CSBS Antikörper
  • CVD1 Antikörper
  • Dilp2 Antikörper
  • Dmel\\CG3937 Antikörper
  • F730004A14Rik Antikörper
  • fb98b06 Antikörper
  • Fil Antikörper
  • filamin-1 Antikörper
  • FLN Antikörper
  • FLN-A Antikörper
  • Fln1 Antikörper
  • flna Antikörper
  • FMD Antikörper
  • joy Antikörper
  • MGC147094 Antikörper
  • MNS Antikörper
  • NHBP Antikörper
  • OPD Antikörper
  • OPD1 Antikörper
  • OPD2 Antikörper
  • RGD1560614 Antikörper
  • sko Antikörper
  • wu:fb98b06 Antikörper
  • wu:fd09g03 Antikörper
  • wu:fd18g06 Antikörper
  • wu:fd49a06 Antikörper
  • XLVD Antikörper
  • XMVD Antikörper

Bezeichner auf Proteinebene für FLNA

fd09g03 , filamin A, alpha (actin binding protein 280) , filamin B, like , filamin A, alpha , filamin-A , CG3937-PA , CG3937-PB , CG3937-PF , CG3937-PG , CG3937-PH , CG3937-PI , CG3937-PK , CG3937-PL , CG3937-PM , CG3937-PN , Filamin-1 , Filamin-A , cher-PA , cher-PB , cher-PF , cher-PG , cher-PH , cher-PI , cher-PK , cher-PL , cher-PM , cher-PN , filamin , filamin B , filamin isoform B , filamin-240 , shi kong , actin binding protein 280 , alpha-filamin , endothelial actin-binding protein , filamin-1 , non-muscle filamin , Endothelial actin-binding protein 280) , filamin, alpha , 450 kDa protein , FLN-A , GENA 379 , actin-binding protein 280 , dilated pupils 2 , filamin A

GENE ID SPEZIES
562529 Danio rerio
699524 Macaca mulatta
569979 Danio rerio
587317 Strongylocentrotus purpuratus
779840 Xenopus (Silurana) tropicalis
100137263 Papio anubis
42066 Drosophila melanogaster
100380643 Salmo salar
2316 Homo sapiens
293860 Rattus norvegicus
481084 Canis lupus familiaris
733585 Sus scrofa
281165 Bos taurus
100328754 Oryctolagus cuniculus
100725162 Cavia porcellus
395261 Gallus gallus
101120390 Ovis aries
192176 Mus musculus
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