anti-Human SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antikörper für Enzyme Immunoassay

Recommended SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
  • CG4494
  • Dm0342
  • DmSUMO-1
  • DmSmt3
  • Dmel\\CG4494
  • Dmsmt3
  • SMT3
  • SUMO
  • Smt3
  • Sumo
  • anon-EST:Posey240
  • dSmt3
  • dsmt3
  • l(2)04493
  • l(2)SH0182
  • l(2)SH2 0182
  • sumo
  • DAP1
  • GMP1
  • OFC10
  • PIC1
  • SENP2
  • SMT3C
  • SMT3H3
  • UBL1
  • 4921531N22Rik
  • AI789753
  • AU040360
  • hm:zeh0670
  • wu:fb74c02
  • wu:fd12c02
  • zgc:65934
  • zgc:85634
  • SUMO1
  • dap1
  • gmp1
  • ofc10
  • pic1
  • senp2
  • smt3
  • smt3c
  • sumo-1
  • sumo1
  • ubl1
  • xsumo-1
  • xsumo1
  • ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1
  • ATSUMO1
  • F10M23.180
  • F10M23_180
  • SMALL UBIQUITIN-LIKE MODIFIER 1
  • SUM1
  • SUMO 1
  • small ubiquitin-like modifier 1
  • pigSUMO1
  • SENTRIN
  • SMTP3
  • SUMO-1
  • Smt3C
  • Ubl1
  • DAP-1
  • Gkap
  • CG4494 gene product from transcript CG4494-RA
  • small ubiquitin-like modifier 1
  • death-associated protein
  • small ubiquitin-like modifier 1 S homeolog
  • small ubiquitin-related protein 1
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • death associated protein
  • DLG associated protein 1
  • smt3
  • Sumo1
  • SUMO1
  • Dap
  • sumo1
  • sumo1.S
  • sumo-1
  • DAP
  • Dlgap1
Epitop
C-Term
47
16
15
14
13
7
7
6
5
4
3
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus
348
153
109
9
8
7
7
6
5
3
3
2
2
1
1
1
1
1
Wirt
Kaninchen
214
128
4
2
2
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
17
15
14
10
10
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Applikation
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
274
135
134
120
110
109
67
53
40
39
10
9
6
2
1
Hersteller
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Bilder

Produktnummer ABIN356734
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN356808 EIA IHC (p) WB Rabbit Ig Anmelden zum Anzeigen Polyclonal 7
1 ABIN955007 EIA FACS IHC (p) WB Rabbit Ig Anmelden zum Anzeigen Polyclonal 5
1 ABIN356380 EIA WB Mouse IgG1 Anmelden zum Anzeigen 66AT1273-94
1 ABIN5552006 EIA IHC (p) WB Rabbit Ig Fraction Anmelden zum Anzeigen Polyclonal
1 ABIN5556656 EIA WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN356802 EIA WB Rabbit Ig C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN5555278 EIA IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) Antikörper
Epitop C-Term
(47), (16), (15), (14), (13), (7), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(348), (153), (109), (9), (8), (7), (7), (6), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(214), (128), (4), (2), (2), (1), (1)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(17), (15), (14), (10), (10), (7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Applikation Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(274), (135), (134), (120), (110), (109), (67), (53), (40), (39), (10), (9), (6), (2), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody is specific to SUMO1 (C-term).
Reinigung Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SUMO1.
Isotyp Ig

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung SUMO1 (SUMO1 Antibody Abstract)
Hintergrund Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.Synonyms: GAP-modifying protein 1, GMP1, SMT3 homolog 3, SMT3C, SMT3H3, Sentrin, Small ubiquitin-related modifier 1, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1
Gen-ID 7341, 9606
UniProt P63165
Forschungsgebiet Signaling, Proteases, DNA/RNA
Pathways M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence (see Ref.6).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Rathke, Baarends, Jayaramaiah-Raja, Bartkuhn, Renkawitz, Renkawitz-Pohl: "Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila." in: Journal of cell science, Vol. 120, Issue Pt 9, pp. 1689-700, 2007

Yang, Sharrocks: "SUMO promotes HDAC-mediated transcriptional repression." in: Molecular cell, Vol. 13, Issue 4, pp. 611-7, 2004

Ling, Sankpal, Robertson, McNally, Karpova, Robertson: "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription." in: Nucleic acids research, Vol. 32, Issue 2, pp. 598-610, 2004

Bailey, OHare: "Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 692-703, 2003

Pountney, Huang, Burns, Haan, Thompson, Blumbergs, Gai: "SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease." in: Experimental neurology, Vol. 184, Issue 1, pp. 436-46, 2003

Ohshima, Shimotohno: "Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 50833-42, 2003

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
 image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (C-Term) antibody (ABIN356734) anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (C-Term) antibody
 image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (C-Term) antibody (ABIN356734) anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (C-Term) antibody (Image 2)
 image for anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (C-Term) antibody (ABIN356734) anti-SMT3 Suppressor of Mif Two 3 Homolog 1 (S. Cerevisiae) (SUMO1) (C-Term) antibody (Image 3)