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Human STAT3 ELISA Kit für Cell ELISA - ABIN1981839
Kanai, Konda, Nakajima, Izumi, Kanda, Nanakin, Kubohara, Chiba: Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway. in Oncogene 2003
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Human STAT3 ELISA Kit für Sandwich ELISA - ABIN625232
Sharma, Yang, Xi, Grotta, Aronowski, Savitz: IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways. in Brain research 2011
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Human STAT3 ELISA Kit für Sandwich ELISA - ABIN625245
Tukaj, Grüner, Tukaj, Zillikens, Kasperkiewicz: Calcitriol exerts anti-inflammatory effects in keratinocytes treated with autoantibodies from a patient with bullous pemphigoid. in Journal of the European Academy of Dermatology and Venereology : JEADV 2015
Stat3 mediates the expression of iNOS (zeige NOS2 ELISA Kits) to promote IFNgamma/TNFalpha (zeige TNF ELISA Kits)-induced muscle atrophy.
BMI1 (zeige BMI1 ELISA Kits) and MEL18 (zeige PCGF2 ELISA Kits) contribute to the development of colitis-associated cancer in mice by promoting proliferation and reducing apoptosis via suppressing expression of Reg3b. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells.
In this study, chronic UVB irradiation induced the expression of IL-10 (zeige IL10 ELISA Kits) and JAK1 (zeige JAK1 ELISA Kits) that eventually activates the STAT3 which leads to the transcription of proliferative and antiapoptotic markers.
Binding of signal transducer and activator of transcription 3 (STAT3) to cyclophilin D (CypD) was important for reducing mitochondrial reactive oxygen species (ROS) production after oxidative stress.
p65 (zeige NFkBP65 ELISA Kits) expression correlates with elevated total cellular levels of STAT3 and STAT1 (zeige STAT1 ELISA Kits) and supports activation of these transcription factors.
Thermal injury of the skin induces G-CSF (zeige CSF3 ELISA Kits)-dependent attenuation of EPO (zeige EPO ELISA Kits)-mediated STAT (zeige STAT1 ELISA Kits) signaling and erythroid differentiation arrest in mice
C/EBPbeta (zeige CEBPB ELISA Kits) or Stat3 depletion by siRNA in sepsis Gr1 (zeige GSR ELISA Kits)(+)CD11b (zeige ITGAM ELISA Kits)(+) MDSCs inhibits miR (zeige MLXIP ELISA Kits)-21 and miR (zeige MLXIP ELISA Kits)-181b expression.
activation of STAT3 in MDSCs and macrophages promoted tumorigenesis through pulmonary recruitment and increased resistance of suppressive cells to CD8 (zeige CD8A ELISA Kits)(+) T cells, enhancement of cytotoxicity toward CD4 (zeige CD4 ELISA Kits)(+) and CD8 (zeige CD8A ELISA Kits)(+) T cells, induction of regulatory T cell (Treg), inhibition of dendritic cells (DC), and polarization of macrophages toward the M2 phenotype.
these data suggest that ROCK2 (zeige ROCK2 ELISA Kits) signaling plays a critical role in controlling the development of TFH cells induced by autoimmune conditions through reciprocal regulation of STAT3 and STAT5 (zeige STAT5A ELISA Kits) activation.
data reveal a previously unrecognized STAT3-mediated immunosuppressive mechanism in DCs and indicate that DC-intrinsic ID2 promotes tumor immunity by modulating tumor-associated CD4 (zeige CD4 ELISA Kits)(+) T cell responses.
Data show that IKKalpha (zeige CHUK ELISA Kits) directly bind to the promoters of LGR5 (zeige LGR5 ELISA Kits), in turn, upregulating LGR5 (zeige LGR5 ELISA Kits) expression through activation of STAT3 signaling pathway during cancer progression.
Enterovirus 71 antagonizes the antiviral activity of host STAT3 and IL-6R with partial dependence on virus-induced miR (zeige MLXIP ELISA Kits)-124.
IL-10 (zeige IL10 ELISA Kits) stimulation activated the JAK (zeige JAK3 ELISA Kits)/Stat-3 and PI3K (zeige PIK3CA ELISA Kits)/Akt (zeige AKT1 ELISA Kits) signaling pathways. Moreover, IL-10 (zeige IL10 ELISA Kits) treatment increased translocation of p65 NF-kappaB (zeige NFkBP65 ELISA Kits) into the nuclear compartment, and up-regulated expression of the pro-survival proteins Bcl-2 (zeige BCL2 ELISA Kits) and Bcl-xL (zeige BCL2L1 ELISA Kits).
these data document the S-nitrosylation mediated inhibition of multiple myeloma (MM) cell proliferation and cell survival via inhibition of STAT3 and NF-kappaB (zeige NFKB1 ELISA Kits) pathways and its efficacy in animal model of MM
6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiated the inhibitory effect of IFN-alpha (zeige IFNA ELISA Kits) on hepatocellular carcinoma cell proliferation through activation of the JAK (zeige JAK3 ELISA Kits)/STAT (zeige STAT1 ELISA Kits) signaling pathway by inhibiting SOCS3 (zeige SOCS3 ELISA Kits) expression.
Results show that STAT3 expression is under the regulation of MiR (zeige MLXIP ELISA Kits)-125b which targets its 3'UTR (zeige UTS2R ELISA Kits).
These findings revealed that miR (zeige MLXIP ELISA Kits)-138 might promote angiogenesis of human cytomegalovirus (HCMV)-infected HUVECs by activating the SIRT1 (zeige SIRT1 ELISA Kits)-mediated p-STAT3 pathway, and this could provide novel insights into HCMV-induced angiogenesis
TGR5 (zeige GPBAR1 ELISA Kits) exhibits significantly higher expression in NSCLC tumor samples and facilitates the growth and metastasis of NSCLC by activating the JAK2 (zeige JAK2 ELISA Kits)/STAT3 signaling pathway.
Data indicate strategies to improve the effectiveness of EGFR (zeige EGFR ELISA Kits) inhibition particularly by blocking the STAT3 pathway.
The IL-34 (zeige IL34 ELISA Kits)/STAT3/miR (zeige MLXIP ELISA Kits)-21 pathway is crucial for the survival of synovial fibroblasts in rheumatoid arthritis
STA3 (zeige ARHGEF3 ELISA Kits) facilitates TLR4 (zeige TLR4 ELISA Kits)-dependent IL-6 (zeige IL6 ELISA Kits) and IL-8 (zeige IL8 ELISA Kits) production via IL-6 (zeige IL6 ELISA Kits) receptor-positive feedback in endometrial cells.
STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.
Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate
results show for the first time that interleukin-6 (zeige IL6 ELISA Kits) (IL), in the presence of its soluble receptor (zeige IFNAR1 ELISA Kits) (sIL (zeige STIL ELISA Kits)-6R), induces activation of JAK1 (zeige JAK1 ELISA Kits), JAK2 (zeige JAK2 ELISA Kits), and STAT1 (zeige STAT1 ELISA Kits)/STAT3 proteins in bovine articular chondrocytes
peroxynitrite causes increased expression of VEGF (zeige VEGFA ELISA Kits) in vascular endothelial cells by a process that requires the activation of STAT3
Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (zeige NOX1 ELISA Kits)-mediated activation of STAT3.
this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets
maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (zeige CCND2 ELISA Kits) and PSEN1 (zeige PSEN1 ELISA Kits) genes via a STAT3-dependent pathway
Studied effect of recombinant porcine leukemia inhibitory factor (zeige LIF ELISA Kits) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (zeige FTH1 ELISA Kits)-supplemented media.
Data suggest that IL-6 (interleukin 6 (zeige IL6 ELISA Kits)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (zeige IL6 ELISA Kits)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).
the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.
Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.
STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways
Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.
This is the first report of the genetic polymorphisms of the JAK1 (zeige JAK1 ELISA Kits) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.
Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.
Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (zeige MMP2 ELISA Kits) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.
Stat3 regulates cell proliferation and axis extension in part via upregulation of Cdc25a (zeige CDC25A ELISA Kits) expression during oogenesis. Accordingly, restoring Cdc25a (zeige CDC25A ELISA Kits) expression in stat3 mutants partially suppressed cell proliferation and gastrulation defects.
PTPN9 (zeige PTPN9 ELISA Kits) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (zeige GATA1 ELISA Kits) and ZBP-89 (zeige ZNF148 ELISA Kits).
Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.
Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.
This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.
The results of this study suggested that the stat3/socs3 (zeige SOCS3 ELISA Kits) pathway is a key response in all tissue regeneration in zebrafish.
stat3, a known oncogene (zeige RAB1A ELISA Kits) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.
Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (zeige PRCP ELISA Kits) in neighboring cells during zebrafish gastrulation.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
signal transducer and activator of transcription 3 (acute-phase response factor)
, signal transducer and activator of transcription 3
, signal transduction and activation of transcription 3
, Signal transducer and activator of transcription 3
, signal transducer and activator of transcription 3-like
, acute phase response factor
, acute-phase response factor
, DNA-binding protein APRF
, Protein Stat3
, signal transducer and activator of transcription 3.1
, stat 3