anti-Schwein IL6ST Antikörper für Immunofluorescence

Recommended IL6ST Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) Antikörper
  • CD130
  • CDW130
  • GP130
  • IL-6RB
  • 5133400A03Rik
  • AA389424
  • BB405851
  • D13Ertd699e
  • gp130
  • Ac1055
  • Gp130
  • Il-6rb
  • NCR
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • interleukin 6 signal transducer
  • neutrophil migration
  • IL6ST
  • Il6st
  • il6st
  • LOC100349330
  • NM
Reaktivität
Human, Maus, Schwein
220
128
64
4
3
3
2
2
1
1
1
1
Wirt
Kaninchen
143
111
72
5
3
2
Klonalität
Polyklonal
Konjugat
Dieser IL6ST Antikörper ist unkonjugiert
21
17
14
14
14
13
12
11
11
11
10
8
7
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
187
123
62
31
26
18
17
13
13
12
11
11
6
6
5
3
2
2
2
1
1
Hersteller
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Bilder

Produktnummer ABIN272005
$ 390.50
Zzgl. Versandkosten $45.00

General

Antigen Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) Antikörper
Reaktivität Human, Maus, Schwein
(220), (128), (64), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(143), (111), (72), (5), (3), (2)
Klonalität
Polyklonal
Konjugat Dieser IL6ST Antikörper ist unkonjugiert
(21), (17), (14), (14), (14), (13), (12), (11), (11), (11), (10), (8), (7), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(187), (123), (62), (31), (26), (18), (17), (13), (13), (12), (11), (11), (6), (6), (5), (3), (2), (2), (2), (1), (1)
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Produktdetails anti-IL6ST Antikörper

Target Details IL6ST Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects endogenous levels of CD130/gp130 protein. (region surrounding Ser778)
Kreuzreaktivität (Details) Species reactivity (tested):Human, Mouse.
Reinigung Affinity Chromatography using epitope-specific immunogen.

Target Details IL6ST

Produktdetails anti-IL6ST Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CD130 / IL6ST (IL6ST Antibody Abstract)
Hintergrund IL-6 activates intracellular signaling through binding a receptor consisting of an 80 kDa ligand-binding protein (IL-6R) and a second protein of 130 kDa. IL-6 first binds to IL-6R which subsequently associates with a gp130 dimer. The active signaling complex consists of at minimum IL-6, IL-6R and a dimer of two gp130 proteins that are linked by a disulfide bond. A soluble form of IL-6R is generated by proteolytic cleavage of the membrane-bound precursor and can function as an agonistic molecule that can actively participate in cell-tocell signaling. The second subunit of the IL-6 complex, gp130, also functions as a component of several additional receptor complexes including leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF) and IL-11. LIF binds to the LIF receptor with low affinity and to a complex of the LIF receptor and gp130 with high affinity, while OSM appears to bind to gp130 with low affinity and to a complex of gp130 and the LIF receptor with high affinity.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
Molekulargewicht approx. 160 kDa
Gen-ID 3572
NCBI Accession NP_002175
UniProt P40189
Forschungsgebiet CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signalweg, Cellular Glucan Metabolic Process, Autophagie, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Handhabung Bilder zurück nach oben
Applikationshinweise ELISA: 1: 20000approx. 1: 40000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Bilder

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
 image for anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody (ABIN272005) anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody
 image for anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody (ABIN272005) anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody (Image 2)