anti-Human IL6ST Antikörper für Enzyme Immunoassay

Recommended IL6ST Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) Antikörper
  • CD130
  • CDW130
  • GP130
  • IL-6RB
  • 5133400A03Rik
  • AA389424
  • BB405851
  • D13Ertd699e
  • gp130
  • Ac1055
  • Gp130
  • Il-6rb
  • NCR
  • interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • interleukin 6 signal transducer
  • neutrophil migration
  • IL6ST
  • Il6st
  • il6st
  • LOC100349330
  • NM
Epitop
AA 878-906, C-Term
29
29
19
15
15
14
14
14
13
13
9
5
5
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human
220
129
64
4
4
3
2
2
1
1
1
1
Wirt
Kaninchen
143
111
72
5
3
2
Klonalität
Polyklonal
Konjugat
Dieser IL6ST Antikörper ist unkonjugiert
21
17
14
14
14
13
12
11
11
11
10
8
7
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
187
123
62
31
26
18
17
14
13
12
11
11
6
5
5
3
2
2
2
1
1
Hersteller
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Bilder

Produktnummer ABIN951186
$ 390.50
Zzgl. Versandkosten $45.00
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1 ABIN2717281 EIA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) Antikörper
Epitop AA 878-906, C-Term
(29), (29), (19), (15), (15), (14), (14), (14), (13), (13), (9), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(220), (129), (64), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(143), (111), (72), (5), (3), (2)
Klonalität
Polyklonal
Konjugat Dieser IL6ST Antikörper ist unkonjugiert
(21), (17), (14), (14), (14), (13), (12), (11), (11), (11), (10), (8), (7), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(187), (123), (62), (31), (26), (18), (17), (14), (13), (12), (11), (11), (6), (5), (5), (3), (2), (2), (2), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-IL6ST Antikörper

Target Details IL6ST Anwendungsinformationen Handhabung Referenzen für anti-IL6ST Antikörper (ABIN951186) Bilder
Spezifität This antibody reacts to CD130.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 878-906 amino acids from the C-terminal region of human CD130
Isotyp Ig

Target Details IL6ST

Produktdetails anti-IL6ST Antikörper Anwendungsinformationen Handhabung Referenzen für anti-IL6ST Antikörper (ABIN951186) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD130 / IL6ST (IL6ST Antibody Abstract)
Hintergrund The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
Molekulargewicht 103537 Da
Gen-ID 3572
NCBI Accession NP_002175
Forschungsgebiet CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signalweg, Cellular Glucan Metabolic Process, Autophagie, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Handhabung Referenzen für anti-IL6ST Antikörper (ABIN951186) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Anwendungsinformationen Referenzen für anti-IL6ST Antikörper (ABIN951186) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-IL6ST Antikörper (ABIN951186)

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Goette, Lev, Heller, Glembotsky, Chazarreta, Salim, Molinas, Marta: "Abnormal regulation of soluble and anchored IL-6 receptor in monocytes from patients with essential thrombocythemia." in: Experimental hematology, Vol. 38, Issue 10, pp. 868-876.e1, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Richards, Nowell, Horiuchi, McLoughlin, Fielding, Grau, Yamamoto, Ehrmann, Rose-John, Williams, Topley, Jones: "Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis." in: Arthritis and rheumatism, Vol. 54, Issue 5, pp. 1662-72, 2006

Bilder

Produktdetails anti-IL6ST Antikörper Target Details IL6ST Anwendungsinformationen Handhabung Referenzen für anti-IL6ST Antikörper (ABIN951186) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 878-906), (C-Term) antibody (ABIN951186) CD130 Antibody (C-term) immunohistochemistry analysis in formalin fixed and par...
Western Blotting (WB) image for anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) (AA 878-906), (C-Term) antibody (ABIN951186) CD130 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (3...