anti-Maus IL12A Antikörper für Functional Studies

Recommended IL12A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interleukin 12 alpha (IL12A) Antikörper
  • IL-12p35
  • Il-12a
  • Ll12a
  • p35
  • CLMF
  • IL-12A
  • NFSK
  • NKSF1
  • P35
  • IL12p35
  • Il-12 p35
  • IL12
  • interleukin 12a
  • interleukin 12A
  • interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Il12a
  • IL12A
Reaktivität
Maus
90
26
5
5
4
4
2
2
1
Wirt
Ratte
48
30
16
4
3
Klonalität
Monoklonal
Konjugat
Dieser IL12A Antikörper ist unkonjugiert
11
5
4
3
2
2
2
2
1
1
1
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
71
47
21
15
15
14
6
4
3
3
2
2
2
2
2
2
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN115777
$ 253.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN116323 EIA Func WB Goat Anmelden zum Anzeigen Polyclonal
1 ABIN116324 EIA Func WB Goat Anmelden zum Anzeigen Polyclonal

General

Antigen Interleukin 12 alpha (IL12A) Antikörper
Reaktivität Maus
(90), (26), (5), (5), (4), (4), (2), (2), (1)
Wirt Ratte
(48), (30), (16), (4), (3)
Klonalität
Monoklonal
Konjugat Dieser IL12A Antikörper ist unkonjugiert
(11), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
(71), (47), (21), (15), (15), (14), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-IL12A Antikörper

Target Details IL12A Anwendungsinformationen Handhabung Bilder
Spezifität Detects Mouse IL-12. Other species not tested.
Reinigung Affinity Chromatography on Protein G
Immunogen Recombinant murine IL-12
Isotyp IgG1

Target Details IL12A

Produktdetails anti-IL12A Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Interleukin-12 alpha / IL12A (IL12A Antibody Abstract)
Hintergrund Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
Gen-ID 16159
NCBI Accession NP_032377
UniProt P43431
Pathways JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-IL12A Antikörper Target Details IL12A Handhabung Bilder zurück nach oben
Applikationshinweise ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 3-4 μg/mL of thisantibody will detect at least 0.1 ng/well of recombinant murine IL-12 when used withbiotinylated antigen affinity purified anti-murine IL-12 as the detection antibody. Neutralisation: To yield one-half maximal inhibition (ND50) of the biological activity ofmurine IL-12 (2.0 ng/mL), a concentration of 0.16-0.24 μg/mL of this antibody is required. Western Blot: To detect mIL-12 by Western Blot analysis this antibody can be used at aconcentration of 2.0-4.0 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant mIL-12 is 1.0-2.0 ng/lane, under reducing conditionsand 0.25-0.50 ng/lane, under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-IL12A Antikörper Target Details IL12A Anwendungsinformationen Bilder zurück nach oben
Rekonstitution Restore in sterile water to a concentration of 1.0 mg/mL.
Buffer PBS without preservatives
Konservierungsmittel Without preservative
Handhabung Avoid repeated freezing and thawing. Protect from light!
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody at 2-8 °C under subdued light for one month or (in aliquots) at -20 °C for longer.