TRAF3IP1 Proteine (TRAF3IP1)

Bezeichnung:
TNF Receptor-Associated Factor 3 Interacting Protein 1 Proteine (TRAF3IP1)
Auf www.antikoerper-online.de finden Sie aktuell 5 TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF3IP1 Antikörper (62) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 75 TRAF3IP1 Produkte verfügbar.
Synonyme:
3930402D05Rik, AU041749, Elipsa, MGC184660, MIP-T3, MIPT3, zgc:63522
alle Proteine anzeigen Gen GeneID UniProt
TRAF3IP1 26146 Q8TDR0
Ratte TRAF3IP1 TRAF3IP1 363286 Q5XIN3
TRAF3IP1 74019 Q149C2

Weitere Synonyme anzeigen

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Weitere Proteine zu TRAF3IP1 Interaktionspartnern

Zebrafish TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) Interaktionspartner

  1. Traf3ip1 is a negative regulator of microtubule stability. Microtubule defects caused by traf3ip1 KO are associated with altered epithelialization/polarity in renal cells and with pronephric cysts and microphthalmia in zebrafish embryos.

  2. Data show that elipsa encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8 (zeige RAB8A Proteine), a small GTPase (zeige RACGAP1 Proteine), known to localize to cilia.

Human TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) Interaktionspartner

  1. Mutations in TRAF3IP1 are identified in patients with nephronophthisis and retinal degeneration. The identified mutations result in mild ciliary defects in patients and reveal a role of IFT54 as a negative regulator of microtubule stability via MAP4 (zeige MAP4 Proteine).

  2. MIP-T3 functions as a negative regulator of the innate type I interferon (zeige IFNA Proteine) response by preventing TRAF3 (zeige TRAF3 Proteine) from forming protein complexes with critical downstream transducers and effectors of antiviral response.

  3. Data show that MIP-T3 protein level is highly regulated; mainly mediated by the ubiquitin-proteasome system.

  4. The interaction of MIP-T3 with both actin filaments and microtubule suggested that MIP-T3 may play an important role in regulation of cytoskeleton dynamics in cells.

  5. These results suggest that MIP-T3 is a novel inhibitor of IL-13 (zeige IL13 Proteine) signaling and may be a useful molecule in ameliorating various conditions in which IL-13 (zeige IL13 Proteine) plays a central role.

Mouse (Murine) TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) Interaktionspartner

  1. Homozygous Traf3ip1 mutants are not viable and have both neural developmental defects and polydactyly, phenotypes typical of mutants with ciliary assembly defects.

  2. Data show that overexpression of IFT54/Traf3ip1 displaces IFT20 (zeige IFT20 Proteine) from the Golgi apparatus. IFT54s effect on IFT20 (zeige IFT20 Proteine) is a dominant negative phenotype caused by its overexpression.

TRAF3IP1 Protein Überblick

Protein Überblick

Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity).

Alternative names and synonyms associated with TRAF3IP1

  • TNF receptor-associated factor 3 interacting protein 1 (traf3ip1)
  • TNF receptor-associated factor 3 interacting protein 1 (TRAF3IP1)
  • TNF receptor-associated factor 3 interacting protein 1 (Traf3ip1)
  • TRAF3 interacting protein 1 (Traf3ip1)
  • 3930402D05Rik Protein
  • AU041749 Protein
  • Elipsa Protein
  • MGC184660 Protein
  • MIP-T3 Protein
  • MIPT3 Protein
  • zgc:63522 Protein

Bezeichner auf Proteinebene für TRAF3IP1

TRAF3-interacting protein 1 , eli , mipt3 , TNF receptor-associated factor 3 interacting protein 1 , TRAF3-interacting protein 1-like , interleukin 13 receptor alpha 1-binding protein-1 , interleukin-13 receptor alpha 1-binding protein 1 , microtubule interacting protein that associates with TRAF3 , microtubule-interacting protein associated with TRAF3 , microtubule-interacting protein that associates with TRAF3

GENE ID SPEZIES
393572 Danio rerio
504984 Bos taurus
607339 Canis lupus familiaris
696594 Macaca mulatta
771149 Gallus gallus
779507 Xenopus (Silurana) tropicalis
100009843 Monodelphis domestica
100066684 Equus caballus
100411296 Callithrix jacchus
100434239 Pongo abelii
742394 Pan troglodytes
100079320 Ornithorhynchus anatinus
100597393 Nomascus leucogenys
26146 Homo sapiens
363286 Rattus norvegicus
74019 Mus musculus
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