anti-ERN1 (ERN1) Antikörper

Bezeichnung:
anti-Endoplasmic Reticulum To Nucleus Signaling 1 Antikörper (ERN1)
Auf www.antikoerper-online.de finden Sie aktuell 210 Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ERN1 Kits (36) und ERN1 Proteine (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 275 ERN1 Produkte verfügbar.
Synonyme:
9030414B18Rik, AI225830, C85377, Ern1, hIRE1p, IRE1, IRE1a, Ire1alpha, Ire1b, IRE1P, RGD1559716

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anti-Mouse (Murine) ERN1 Antikörper:

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Am meisten referenzierte anti-ERN1 Antikörper

  1. Human Polyclonal ERN1 Primary Antibody für ELISA, ICC - ABIN250706 : Lipson, Fonseca, Ishigaki, Nguyen, Foss, Bortell, Rossini, Urano: Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. in Cell metabolism 2006 (PubMed)
    Zeige alle 140 Referenzen für 250706

  2. Human Polyclonal ERN1 Primary Antibody für ICC, IF - ABIN250711 : Kubota, Lee, Tsuchiya, Young, Everett, Martinez-Mier, Snead, Nguyen, Urano, Bartlett: Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 17 Referenzen für 250711

  3. Human Monoclonal ERN1 Primary Antibody für ELISA, IHC (p) - ABIN1999391 : Trentmann: ERN1, a novel ethylene-regulated nuclear protein of Arabidopsis. in Plant molecular biology 2000 (PubMed)
    Zeige alle 3 Referenzen für 1999391

  4. Human Monoclonal ERN1 Primary Antibody für IHC, ELISA - ABIN969116 : Huang, Tan, Yoshida, Mori, Ma, Yen: Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress. in Molecular and cellular biology 2005 (PubMed)
    Zeige alle 3 Referenzen für 969116

  5. Human Polyclonal ERN1 Primary Antibody für IF (p), IHC (p) - ABIN1387531 : Xu, Su, Song, Shi, Fu, Hu, Xia, Song, Song: Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release. in Chemical research in toxicology 2015 (PubMed)
    Zeige alle 2 Referenzen für 1387531

  6. Human Polyclonal ERN1 Primary Antibody für ELISA, ICC - ABIN250707 : Luo, He, Zhang, Yu, Chen, Xu, Tang, Urano, Min: AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. in The Journal of biological chemistry 2008 (PubMed)
    Zeige alle 2 Referenzen für 250707

  7. Human Polyclonal ERN1 Primary Antibody für ELISA, WB - ABIN316350 : Yokouchi, Hiramatsu, Hayakawa, Okamura, Du, Kasai, Takano, Shitamura, Shimada, Yao, Kitamura: Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response. in The Journal of biological chemistry 2008 (PubMed)

  8. Human Polyclonal ERN1 Primary Antibody für IHC (fro), IF - ABIN318703 : Zhang, Kaufman: Signaling the unfolded protein response from the endoplasmic reticulum. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen ERN1 Interaktionspartner

Mouse (Murine) Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) Interaktionspartner

  1. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

  2. defective autophagy in intestinal epithelial cells (IECs) may predispose to Crohn's disease ileitis via impaired clearance of IRE1alpha aggregates during ER stress at this site.

  3. The findings indicate that IRE1-XBP1 (zeige XBP1 Antikörper) downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  4. the ABL (zeige ABL1 Antikörper) family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  5. We reveal distinct binding affinities between the binary and ternary complexes thus formed, that suggest a preference for the PERK (zeige EIF2AK3 Antikörper) signaling branch under stress, and a predilection for the GRP78 (zeige HSPA5 Antikörper)-UPR sensor complex formation upon stressor removal. These results imply a gated UPR mechanism that tunes the overall cellular behavior to the accumulation of unfolded proteins.

  6. Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs.

  7. Ire1alpha-Xbp1s and associated molecular targets link ER stress in arcuate Pomc (zeige POMC Antikörper) neurons to aspects of normal energy and glucose homeostasis.

  8. heat stress simultaneously activates both the unfolded protein response (UPR) and autophagy, followed by the activation of a negative feedback system in UPR by modulating the responses related to the IRE1alpha-XBP-1 (zeige XBP1 Antikörper) axis.

  9. this study shows that IRE1alpha is a critical switch governing M1-M2 macrophage polarization and energy balance in obesity

  10. Findings indicate that PERK (zeige EIF2AK3 Antikörper) kinase-activating transcription factor 4 (ATF4 (zeige ATF4 Antikörper)) pathway affected the efficiency of X-box binding protein 1 (XBP1 (zeige XBP1 Antikörper)) mRNA splicing by regulating inositol-requiring enzyme 1alpha (IRE1alpha) expression.

Human Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) Interaktionspartner

  1. Results of this investigation demonstrate that inhibition of IRE1 signaling enzyme function affects the expression of NRIP1 (zeige NRIP1 Antikörper), EBBP (zeige TRIM16 Antikörper), ESRRA (zeige ESRRA Antikörper), E2IG5 (zeige FAM162A Antikörper), PGRMC2 (zeige PGRMC2 Antikörper), and SLC39A6 (zeige SLC39A6 Antikörper) genes in U87 glioma cells in gene specific manner and these changes possibly contribute to the suppression of the cell proliferation. Most of these genes are regulated by hypoxia and preferentially through IRE1 signaling pathway of endoplasmic reticulum stress

  2. IRE1alpha was shown to cleave miR (zeige MLXIP Antikörper)-150 and thereby to release the suppressive effect that miR (zeige MLXIP Antikörper)-150 exerted on alphaSMA (zeige ACTA2 Antikörper) expression through c-Myb (zeige MYB Antikörper). Inhibition of IRE1alpha was also demonstrated to block endoplasmic reticulum expansion through an XBP-1 (zeige XBP1 Antikörper)-dependent pathway.

  3. IRE-1 has an ancient function as a cytoplasmic sentinel that activates p38 (zeige CRK Antikörper) and SKN-1(Nrf2 (zeige GABPA Antikörper)). csteine modifications induced by ROS (zeige ROS1 Antikörper) signals can direct proteins to adopt unexpected functions and may coordinate many cellular processes.

  4. The findings indicate that IRE1-XBP1 (zeige XBP1 Antikörper) downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  5. Western blot analysis of subcutaneously implanted AsPC-1 and BxPC-3 tumors as well as orthotopically implanted Panc-1 tumors demonstrated upregulation of BIP (zeige GDF10 Antikörper), CHOP (zeige DDIT3 Antikörper), and IRE1alpha expression in the tumor lysates from penfluridol-treated mice as compared to tumors from control mice

  6. the ABL (zeige ABL1 Antikörper) family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  7. Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK (zeige EIF2AK3 Antikörper) and IRE1 signalings

  8. IRE1 is involved in multivesicular body information during endoplasmic reticulum stress.

  9. Comparison of this structure with other existing structures of IRE1alpha and integration of our extensive structure activity relationship (SAR (zeige SARDH Antikörper)) data has led us to formulate a model to rationalize how ATP-binding site ligands are able to control the IRE1alpha oligomeric state and subsequent RNase domain activity

  10. Our data indicate that reduced response of IRE1alpha/Xbp-1 (zeige XBP1 Antikörper) signaling pathway to bortezomib may contribute to drug resistance in myeloma cells

ERN1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Alternative names and synonyms associated with ERN1

  • endoplasmic reticulum (ER) to nucleus signalling 1 (Ern1) Antikörper
  • endoplasmic reticulum (ER) to nucleus signalling 2 (Ern2) Antikörper
  • endoplasmic reticulum to nucleus signaling 1 (ERN1) Antikörper
  • endoplasmic reticulum to nucleus signaling 1 (Ern1) Antikörper
  • endoplasmic reticulum to nucleus signalling 1 (LOC100357346) Antikörper
  • 9030414B18Rik Antikörper
  • AI225830 Antikörper
  • C85377 Antikörper
  • Ern1 Antikörper
  • hIRE1p Antikörper
  • IRE1 Antikörper
  • IRE1a Antikörper
  • Ire1alpha Antikörper
  • Ire1b Antikörper
  • IRE1P Antikörper
  • RGD1559716 Antikörper

Bezeichner auf Proteinebene für ERN1

endoplasmic reticulum-to-nucleus signaling 1 , inositol-requiring 1 alpha , inositol-requiring protein 1 , ire1-alpha , serine/threonine-protein kinase/endoribonuclease IRE1 , endoplasmic reticulum-to-nucleus signaling 2 , inositol-requiring 1 (Yeast homologue) , inositol-requiring 1 beta , inositol-requiring protein 2 , ire1-beta , mIre1 , serine/threonine-protein kinase/endoribonuclease IRE2 , ER to nucleus signalling 1 , inositol-requiring 1 , inositol-requiring enzyme 1 , protein kinase/endoribonuclease , endoplasmic reticulum (ER) to nucleus signalling 1 , endoplasmic reticulum to nucleus signalling 1

GENE ID SPEZIES
78943 Mus musculus
26918 Mus musculus
2081 Homo sapiens
498013 Rattus norvegicus
100733391 Cavia porcellus
100510978 Sus scrofa
610766 Canis lupus familiaris
524719 Bos taurus
771230 Gallus gallus
101102746 Ovis aries
100357346 Oryctolagus cuniculus
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