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Human TH ELISA Kit für Sandwich ELISA - ABIN414697
Jang, Park, Lee, Lee, Kim, Koh: 1,25-dyhydroxyvitamin D3 attenuates L-DOPA-induced neurotoxicity in neural stem cells. in Molecular neurobiology 2015
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Rat (Rattus) TH ELISA Kit für Sandwich ELISA - ABIN431651
Ren, Ling, Zhou, Han, Zhou, Chen, Li, Kang, Zhu: Silencing salusin-β attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats. in Scientific reports 2017
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Rat (Rattus) TH ELISA Kit für Sandwich ELISA - ABIN457273
Huang, Shih, Chang, Huang, Wu, Chen: [(123)I]Epidepride neuroimaging of dopamine D(2)/D(3) receptor in chronic MK-801-induced rat schizophrenia model. in Nuclear medicine and biology 2012
The Khc73 stalk/14-3-3 (zeige YWHAZ ELISA Kits)/NudE pathway defines a physical connection that coordinates the activities of multiple motor proteins to precisely position the spindle.
role of 14-3-3epsilon in germ cell migration
14-3-3epsilon acts as a biochemical control point for axon guidance in Drosophila, silencing Plexin A repulsive axon guidance and regulating a semaphorin repulsion/integrin adhesion switch.
We conclude that 14-3-3epsilon is required for Rab11 (zeige RAB11A ELISA Kits)-positive vesicle function, which in turn enables antimicrobial peptide (zeige cAMP ELISA Kits) secretion during an innate immune response.
Hpo (zeige GFER ELISA Kits) signaling inhibited Yki (zeige YAP1 ELISA Kits) nuclear localization and activity by phosphorylating Yki (zeige YAP1 ELISA Kits) and both isoforms of 14-3-3 (zeige YWHAZ ELISA Kits), 14-3-3varepsilon and 14-3-3zeta (zeige YWHAZ ELISA Kits), regulate Yki (zeige YAP1 ELISA Kits) activity through modulating its subcellular localization.
The biochemically conserved regulatory mechanisms of recombinant DTH parallel those from mammals.
maternal as well as embryonic effects on the secretion and/or functionality of Tyrosine hydroxylase (pale) may play roles in the early developmental program of the organism.
activity of tyrosine hydroxylase is also increased by this interaction, in excess of the stimulation resulting from phosphorylation alone
Drosophila 14-3-3/PAR-5 (zeige YWHAZ ELISA Kits) is an essential mediator of PAR-1 (zeige F2R ELISA Kits) function in axis formation.
PAR-1 (zeige F2R ELISA Kits) phosphorylates Bazooka/PAR-3 (zeige PARD3 ELISA Kits) on two conserved serines to generate 14-3-3 (zeige YWHAZ ELISA Kits) binding sites. This inhibits formation of the Bazooka (zeige PARD3 ELISA Kits)/PAR-6 (zeige PARD6A ELISA Kits)/aPKC complex by blocking Bazooka (zeige PARD3 ELISA Kits) oligomerization and binding to aPKC.
Results show that the positive rates and expression levels of nestin (zeige NES ELISA Kits), tyrosine hydroxylase (TH), GFAP (zeige GFAP ELISA Kits) and IL-17 (zeige IL17A ELISA Kits) were significantly decreased while Foxp3 (zeige FOXP3 ELISA Kits) and the ratio of Foxp3 (zeige FOXP3 ELISA Kits)/IL-17 (zeige IL17A ELISA Kits) were statistically elevated in BM of AML (zeige RUNX1 ELISA Kits) patients.
Data suggest that TH phosphorylated at Ser (zeige SIGLEC1 ELISA Kits)-31 co-distributes with Golgi complexes and synaptic-like vesicles in rat and human dopaminergic neurons/cell lines; Ser (zeige SIGLEC1 ELISA Kits)-31 phosphorylation may regulate TH subcellular localization by enabling its transport along microtubules, notably toward the projection terminals.
TH is a robust interaction partner of different 14-3-3 (zeige YWHAQ ELISA Kits) dimer types with moderate variability between the 14-3-3 (zeige YWHAQ ELISA Kits) dimers on their regulation of TH.
No statistically significant differences were found between cases and controls for the allele frequencies in five genes: TH, SLC18A2, DRD1 (zeige DRD1 ELISA Kits), DRD3 (zeige DRD3 ELISA Kits) and COMT (zeige COMT ELISA Kits). Conversely, some alleles of the 12 sNPs from the DRD2 (zeige DRD2 ELISA Kits) locus and the 5 from the MAOA (zeige MAOA ELISA Kits) locus showed significant associations with excessive alcohol consumption.
Results show that metastasis-associated protein 1 (MTA1 (zeige MTA1 ELISA Kits)) and tyrosine hydroxylase (TH) levels were significantly down-regulated in Parkinson disease (PD) samples as compared with normal brain tissue
the reduction of tyrosine hydroxylase-immunoreactive neurons occurring in the locus coeruleus after perinatal hypoxic insults persists into adulthood
In high-risk metastatic Neuroblastoma (zeige ARHGEF16 ELISA Kits), TH and DCX (zeige DCX ELISA Kits) mRNA quantification could be used for the assessment of response to treatment and for early detection of progressive disease or relapses.
the allelic frequency of the TH01 marker in 171 Swiss sudden infant death syndrome (SIDS (zeige IDS ELISA Kits)) infants and 500 healthy and gender-matched Caucasian adults showed that the 9.3 allele is similarly distributed in SIDS (zeige IDS ELISA Kits) cases and controls (27.2% vs. 25.6%; p-value = 0.562).
This study showed that a new tyrosine hydroxylase knock-in mouse model of l-DOPA-responsive dystonia.
The mutant tyrosine hydroxylase enzyme was unstable and exhibited deficient stabilization by catecholamines, leading to decline of brain tyrosine hydroxylase-immunoreactivity in the Th knock-in mice.
These findings reveal that Th and Gad1 share a transcription regulatory mechanism that facilitates odorant-dependent regulation of dopamine and GABA expression levels.
deletion of Th in hematopoietic cells of adult mice neither alters energy expenditure upon cold exposure nor reduces browning in inguinal adipose tissue. Bone marrow-derived macrophages did not release NE in response to stimulation with IL-4 (zeige IL4 ELISA Kits), and conditioned media from IL-4 (zeige IL4 ELISA Kits)-stimulated macrophages failed to induce expression of thermogenic genes, such as uncoupling protein 1 (Ucp1 (zeige UCP1 ELISA Kits)), in adipocytes.
The neurogenic contractions were higher in the sickle cell disease, in association with elevated tyrosine hydroxylase phosphorylated at Ser (zeige SIGLEC1 ELISA Kits)-31 and total tyrosine hydroxylase protein expression, as well as increased tyrosine hydroxylase mRNA expression.
these data demonstrate a novel interaction between Hsc70 (zeige HSPA8 ELISA Kits) and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 (zeige HSPA8 ELISA Kits) in dopamine homeostasis.
TH gene overexpression promotes the polarization and differentiation of CD4 (zeige CD4 ELISA Kits)+ cells towards Th2 cells.
The TH-immunopositive fibres detected in the orbitofrontal cortices of the DISC1 (zeige DISC1 ELISA Kits) KO mice were significantly shorter than those seen in the wild-type mice.
Real-time PCR analyses revealed that social defeat significantly increased tyrosine hydroxylase in the ventral tegmental area.
These results revealed a new role of the canonical Lrp5 (zeige LRP5 ELISA Kits)/6-beta-catenin (zeige CTNNB1 ELISA Kits) pathway in regulating the morphogenesis of the cerebellum during postnatal development.
psychostimulants induce downregulation of DRD1a (zeige DRD1 ELISA Kits) and DRD2 (zeige DRD2 ELISA Kits) mRNA expression and upregulation of tyrosine hydroxylase protein expression in the testis
Deletion of the CB2 r (zeige CNR2 ELISA Kits) gene increased preference for and vulnerability to ethanol consumption, at least in part, by increased ethanol-induced sensitivity of the TH and mu-opioid receptor (zeige OPRM1 ELISA Kits) gene expressions in mesolimbic neurons.
Achilles tendon tenocytes produce tyrosine hydroxylase.
Retinol activates tyrosine hydroxylase via two sequential non-genomic mechanisms, which have not previously been characterized. These mechanisms are likely to operate in vivo to facilitate the stress response.
IFN-alpha (zeige IFNA ELISA Kits) mediated activation of ERK1/2 (zeige MAPK1/3 ELISA Kits) appeared to be responsible for the increased phosphorylation of tyrosine hydroxylase.
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
, XBB70 group VII
, drosophila tyrosine hydroxylase
, tyrosine hydrodroxylase
, tyrosine hydroxylase
, tyrosine 3-monooxygenase
, suppressor of Ras85D 3-9
, dystonia 14
, tyrosine 3-hydroxylase