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Bird (Avian) Polyclonal TH Primary Antibody für ICC, IF - ABIN152459
Guo, Lai, Longhurst: Medullary pathways involved in cardiac sympathoexcitatory reflexes in the cat. in Brain research 2001
Show all 47 Pubmed References
Fruit Fly (Drosophila melanogaster) Polyclonal TH Primary Antibody für ICC, IF - ABIN152458
Renfroe, Chronister, Haycock, Waymire: The localization of tyrosine hydroxylase-like immunoreactivity in the central nervous system: methodological considerations. in Brain research bulletin 1984
Show all 68 Pubmed References
Alpaca (Vicugna pacos) Monoclonal TH Primary Antibody für IEM, ICC - ABIN617906
Lundius, Stroth, Vukojević, Terenius, Svenningsson: Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line. in Journal of neurochemistry 2013
Show all 1421 Pubmed References
Human Monoclonal TH Primary Antibody für IHC (fro), IHC (p) - ABIN3043094
Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: S100+ cells: a new neuro-immune cross-talkers in lymph organs. in Scientific reports 2013
Show all 9 Pubmed References
Mammalian Polyclonal TH Primary Antibody für IHC (fro), IF - ABIN361503
Nakashima, Mori, Kaneko, Hayashi, Nagatsu, Ota: Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme. in Biochemical and biophysical research communications 2011
Show all 15 Pubmed References
Rat (Rattus) Polyclonal TH Primary Antibody für IHC (fro), IF - ABIN361502
Kish, Kalasinsky, Derkach, Schmunk, Guttman, Ang, Adams, Furukawa, Haycock: Striatal dopaminergic and serotonergic markers in human heroin users. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001
Show all 12 Pubmed References
Mouse (Murine) Polyclonal TH Primary Antibody für ICC, IHC (fro) - ABIN152518
Lew, Garcia-Espana, Lee, Carr, Goldstein, Haycock, Meller: Increased site-specific phosphorylation of tyrosine hydroxylase accompanies stimulation of enzymatic activity induced by cessation of dopamine neuronal activity. in Molecular pharmacology 1999
Show all 5 Pubmed References
Mouse (Murine) Polyclonal TH Primary Antibody für IF, IHC - ABIN152552
Salvatore, Garcia-Espana, Goldstein, Deutch, Haycock: Stoichiometry of tyrosine hydroxylase phosphorylation in the nigrostriatal and mesolimbic systems in vivo: effects of acute haloperidol and related compounds. in Journal of neurochemistry 2000
Show all 4 Pubmed References
Human Polyclonal TH Primary Antibody für FACS, IF (p) - ABIN723635
Yu, Liao, Liu, Chen, Feng, Fu: Overexpression of lactate dehydrogenase-A in human intrahepatic cholangiocarcinoma: its implication for treatment. in World journal of surgical oncology 2014
Show all 3 Pubmed References
Human Monoclonal TH Primary Antibody für ICC, IF - ABIN151520
Zhang, Ng, Li, He, Anderson, Sun, Zhou: Prokineticin 2 is a target gene of proneural basic helix-loop-helix factors for olfactory bulb neurogenesis. in The Journal of biological chemistry 2007
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The Khc73 stalk/14-3-3 (zeige YWHAZ Antikörper)/NudE pathway defines a physical connection that coordinates the activities of multiple motor proteins to precisely position the spindle.
role of 14-3-3epsilon in germ cell migration
14-3-3epsilon acts as a biochemical control point for axon guidance in Drosophila, silencing Plexin A repulsive axon guidance and regulating a semaphorin repulsion/integrin adhesion switch.
We conclude that 14-3-3epsilon is required for Rab11 (zeige RAB11A Antikörper)-positive vesicle function, which in turn enables antimicrobial peptide (zeige cAMP Antikörper) secretion during an innate immune response.
Hpo (zeige GFER Antikörper) signaling inhibited Yki (zeige YAP1 Antikörper) nuclear localization and activity by phosphorylating Yki (zeige YAP1 Antikörper) and both isoforms of 14-3-3 (zeige YWHAZ Antikörper), 14-3-3varepsilon and 14-3-3zeta (zeige YWHAZ Antikörper), regulate Yki (zeige YAP1 Antikörper) activity through modulating its subcellular localization.
The biochemically conserved regulatory mechanisms of recombinant DTH parallel those from mammals.
maternal as well as embryonic effects on the secretion and/or functionality of Tyrosine hydroxylase (pale) may play roles in the early developmental program of the organism.
activity of tyrosine hydroxylase is also increased by this interaction, in excess (zeige RCC1 Antikörper) of the stimulation resulting from phosphorylation alone
Drosophila 14-3-3/PAR-5 (zeige YWHAZ Antikörper) is an essential mediator of PAR-1 (zeige F2R Antikörper) function in axis formation.
PAR-1 (zeige F2R Antikörper) phosphorylates Bazooka/PAR-3 (zeige PARD3 Antikörper) on two conserved serines to generate 14-3-3 (zeige YWHAZ Antikörper) binding sites. This inhibits formation of the Bazooka (zeige PARD3 Antikörper)/PAR-6 (zeige PARD6A Antikörper)/aPKC complex by blocking Bazooka (zeige PARD3 Antikörper) oligomerization and binding to aPKC.
Data suggest that TH phosphorylated at Ser (zeige SIGLEC1 Antikörper)-31 co-distributes with Golgi complexes and synaptic-like vesicles in rat and human dopaminergic neurons/cell lines; Ser (zeige SIGLEC1 Antikörper)-31 phosphorylation may regulate TH subcellular localization by enabling its transport along microtubules, notably toward the projection terminals.
TH is a robust interaction partner of different 14-3-3 (zeige YWHAQ Antikörper) dimer types with moderate variability between the 14-3-3 (zeige YWHAQ Antikörper) dimers on their regulation of TH.
No statistically significant differences were found between cases and controls for the allele frequencies in five genes: TH, SLC18A2, DRD1 (zeige DRD1 Antikörper), DRD3 (zeige DRD3 Antikörper) and COMT (zeige COMT Antikörper). Conversely, some alleles of the 12 sNPs from the DRD2 (zeige DRD2 Antikörper) locus and the 5 from the MAOA (zeige MAOA Antikörper) locus showed significant associations with excessive alcohol consumption.
Results show that metastasis-associated protein 1 (MTA1 (zeige MTA1 Antikörper)) and tyrosine hydroxylase (TH) levels were significantly down-regulated in Parkinson disease (PD) samples as compared with normal brain tissue
the reduction of tyrosine hydroxylase-immunoreactive neurons occurring in the locus coeruleus after perinatal hypoxic insults persists into adulthood
In high-risk metastatic Neuroblastoma (zeige ARHGEF16 Antikörper), TH and DCX (zeige DCX Antikörper) mRNA quantification could be used for the assessment of response to treatment and for early detection of progressive disease or relapses.
the allelic frequency of the TH01 marker in 171 Swiss sudden infant death syndrome (SIDS (zeige IDS Antikörper)) infants and 500 healthy and gender-matched Caucasian adults showed that the 9.3 allele is similarly distributed in SIDS (zeige IDS Antikörper) cases and controls (27.2% vs. 25.6%; p-value = 0.562).
This study showed that a new tyrosine hydroxylase knock-in mouse model of l-DOPA-responsive dystonia.
The mutant tyrosine hydroxylase enzyme was unstable and exhibited deficient stabilization by catecholamines, leading to decline of brain tyrosine hydroxylase-immunoreactivity in the Th knock-in mice.
Thus, the hTH-GFP reporter rat should be a valuable tool for Parkinson's disease research.
These findings reveal that Th and Gad1 share a transcription regulatory mechanism that facilitates odorant-dependent regulation of dopamine and GABA expression levels.
deletion of Th in hematopoietic cells of adult mice neither alters energy expenditure upon cold exposure nor reduces browning in inguinal adipose tissue. Bone marrow-derived macrophages did not release NE in response to stimulation with IL-4 (zeige IL4 Antikörper), and conditioned media from IL-4 (zeige IL4 Antikörper)-stimulated macrophages failed to induce expression of thermogenic genes, such as uncoupling protein 1 (Ucp1 (zeige UCP1 Antikörper)), in adipocytes.
The neurogenic contractions were higher in the sickle cell disease, in association with elevated tyrosine hydroxylase phosphorylated at Ser (zeige SIGLEC1 Antikörper)-31 and total tyrosine hydroxylase protein expression, as well as increased tyrosine hydroxylase mRNA expression.
these data demonstrate a novel interaction between Hsc70 (zeige HSPA8 Antikörper) and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 (zeige HSPA8 Antikörper) in dopamine homeostasis.
TH gene overexpression promotes the polarization and differentiation of CD4 (zeige CD4 Antikörper)+ cells towards Th2 cells.
The TH-immunopositive fibres detected in the orbitofrontal cortices of the DISC1 (zeige DISC1 Antikörper) KO mice were significantly shorter than those seen in the wild-type mice.
Real-time PCR analyses revealed that social defeat significantly increased tyrosine hydroxylase in the ventral tegmental area.
These results revealed a new role of the canonical Lrp5 (zeige LRP5 Antikörper)/6-beta-catenin (zeige CTNNB1 Antikörper) pathway in regulating the morphogenesis of the cerebellum during postnatal development.
psychostimulants induce downregulation of DRD1a (zeige DRD1 Antikörper) and DRD2 (zeige DRD2 Antikörper) mRNA expression and upregulation of tyrosine hydroxylase protein expression in the testis
Deletion of the CB2 r (zeige CNR2 Antikörper) gene increased preference for and vulnerability to ethanol consumption, at least in part, by increased ethanol-induced sensitivity of the TH and mu-opioid receptor (zeige OPRM1 Antikörper) gene expressions in mesolimbic neurons.
Achilles tendon tenocytes produce tyrosine hydroxylase.
Retinol activates tyrosine hydroxylase via two sequential non-genomic mechanisms, which have not previously been characterized. These mechanisms are likely to operate in vivo to facilitate the stress response.
IFN-alpha (zeige IFNA Antikörper) mediated activation of ERK1/2 (zeige MAPK1/3 Antikörper) appeared to be responsible for the increased phosphorylation of tyrosine hydroxylase.
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
, XBB70 group VII
, drosophila tyrosine hydroxylase
, tyrosine hydrodroxylase
, tyrosine hydroxylase
, tyrosine 3-monooxygenase
, suppressor of Ras85D 3-9
, dystonia 14
, tyrosine 3-hydroxylase