Nibrin (NBN) ELISA Kits

Bezeichnung:
Nibrin ELISA Kits (NBN)
Auf www.antikoerper-online.de finden Sie aktuell 11 Nibrin (NBN) ELISA Kits von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Nibrin Antikörper (261) und Nibrin Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 291 Nibrin Produkte verfügbar.
Synonyme:
AT-V1, AT-V2, ATV, im:6911679, NBN, NBS, Nbs1, P95, zgc:194152

Weitere ELISA Kits für Nibrin Interaktionspartner

Human Nibrin (NBN) Interaktionspartner

  1. The results illuminate the important role of Nbs1 and CtIP (zeige RBBP8 ELISA Kits) in determining the substrates and consequences of human Mre11 (zeige MRE11A ELISA Kits)/Rad50 (zeige RAD50 ELISA Kits) nuclease (zeige DCLRE1C ELISA Kits) activities on protein-DNA lesions.

  2. The Nbs1 homologs that promote herpes simplex virus 1 infection also interact with the herpes simplex virus 1 ICP0 protein.

  3. The CC genotype of NBS1 Glu185Gln may increase lung cancer risk only for males and smokers and may serve as a practical marker for early detective and predictive purposes of lung cancer

  4. surmise that the higher fertility of female c.657del5 carriers reflects a lower miscarriage rate in these women, thereby reflecting the role of the NBN gene product, nibrin, in the repair of DNA double strand breaks and their processing in immune gene rearrangements, telomere maintenance, and meiotic recombination

  5. although Mre11 (zeige MRE11A ELISA Kits) is required for efficient HR-dependent repair of ionizing-radiation-induced DSBs, Mre11 (zeige MRE11A ELISA Kits) is largely dispensable for DSB resection in both chicken DT40 and human TK6 B cell lines.

  6. a somatic missense mutation c.1061C>T (p.P354L) in the NBN gene in a patient with CCS (zeige CCS ELISA Kits) lacking an EWSR1 (zeige EWSR1 ELISA Kits)-ATF1 (zeige AFT1 ELISA Kits) fusion.

  7. The high expression of MRE11 (zeige MRE11A ELISA Kits)-RAD50 (zeige RAD50 ELISA Kits)-NBS1 complex constituents could be a predictor for poor prognosis and chemoresistance in gastric cancer

  8. The overall frequency of c.657del5 in unselected pancreatic ductal adenocarcinoma (PDAC) patients (5/241; 2.07%) significantly differed from that in non-cancer controls (2/915; 0.2%; P=0.006). The result indicates that the NBN c.657del5 variant represents a novel PDAC-susceptibility allele increasing PDAC risk (OR=9.7; 95% CI: 1.9 to 50.2).

  9. mitochondria response to low-dose radiation in radiosensitive human ataxia telangiectasia mutated (ATM (zeige ATM ELISA Kits))- and Nijmegen breakage syndrome (NBS)1-deficient cell lines, was investigated.

  10. Study shows that NBS1 may function in histone modification and in the coordination of chromatin remodeling to promote efficient and effective DNA double-strand break repair. [review]

Mouse (Murine) Nibrin (NBN) Interaktionspartner

  1. findings show that NBS1 is crucial for macrophage function during normal aging

  2. TRIP13 (zeige TRIP13 ELISA Kits)-deficient spermatocytes also progress to an H1t (zeige HIST1H1T ELISA Kits)-positive stage if ATM (zeige ATM ELISA Kits) activity is attenuated by hypomorphic mutations in Mre11 (zeige MRE11A ELISA Kits) or Nbs1 or by elimination of the ATM (zeige ATM ELISA Kits)-effector kinase CHK2 (zeige CHEK2 ELISA Kits)

  3. In the absence of wild type nibrin, the repair of spontaneous errors, presumably arising during DNA replication, makes a major contribution to the basal mutation rate.

  4. Nbs1 mutants initially accumulate replication intermediate, not DSBs.

  5. This report showed that ATM (zeige ATM ELISA Kits)-Chk2 (zeige CHEK2 ELISA Kits)-P53 (zeige TP53 ELISA Kits) signaling pathway and the AKT (zeige AKT1 ELISA Kits)/mTOR (zeige FRAP1 ELISA Kits) signaling pathway are responsible for the enhanced apoptosis of the Nbn-deficient mature oligodendrocytes.

  6. JNK (zeige MAPK8 ELISA Kits) signaling and ATR (zeige ATR ELISA Kits) signaling are likely to converge to regulate the cerebellar apoptosis of newborn Nbn-deficient mice.

  7. Nbn and Atm (zeige ATM ELISA Kits) collaborate to prevent DSB accumulation and apoptosis during development in a tissue- and developmental stage-specific manner.

  8. the antagonism and redundancy of ATMIN and NBS1 constitute a crucial regulatory mechanism for ATM (zeige ATM ELISA Kits) signaling and function.

  9. Nbs1-deficient neocortex shows accumulative endogenous DNA damage and defective activation of Ataxia telangiectasia and Rad3-related (ATR)-Chk1 pathway upon DNA damage.

  10. NBS1 haploinsufficiency results in increased mammary tumor latency and metastasis.

Nibrin (NBN) Antigen-Profil

Beschreibung des Gens

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Alternative names and synonyms associated with Nibrin (NBN)

  • nibrin (NBN) Elisa Kit
  • nibrin (nbn) Elisa Kit
  • nibrin (Nbn) Elisa Kit
  • AT-V1 Elisa Kit
  • AT-V2 Elisa Kit
  • ATV Elisa Kit
  • im:6911679 Elisa Kit
  • NBN Elisa Kit
  • NBS Elisa Kit
  • Nbs1 Elisa Kit
  • P95 Elisa Kit
  • zgc:194152 Elisa Kit

Bezeichner auf Proteinebene für Nibrin (NBN) ELISA Kits

nibrin , Nijmegen breakage syndrome 1 (nibrin) , cell cycle regulatory protein p95 , p95 protein of the MRE11/RAD50 complex , nijmegen breakage syndrome protein 1 homolog

GENE ID SPEZIES
464278 Pan troglodytes
522943 Bos taurus
100480000 Ailuropoda melanoleuca
100526779 Papio anubis
100557161 Anolis carolinensis
100585384 Nomascus leucogenys
4683 Homo sapiens
27354 Mus musculus
85482 Rattus norvegicus
374246 Gallus gallus
100715565 Cavia porcellus
544655 Danio rerio
100172091 Pongo abelii
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