anti-NEIL1 (NEIL1) Antikörper

Bezeichnung:
anti-Endonuclease VIII-Like 1 Antikörper (NEIL1)
Auf www.antikoerper-online.de finden Sie aktuell 68 Endonuclease VIII-Like 1 (NEIL1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NEIL1 Proteine (13) und NEIL1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 96 NEIL1 Produkte verfügbar.
Synonyme:
2810450N13Rik, FPG1, hFPG1, Nei1
Alle Antikörper anzeigen Gen GeneID UniProt
NEIL1 367090  
NEIL1 79661 Q96FI4
NEIL1 72774 Q8K4Q6

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-NEIL1 (NEIL1) Antikörper

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anti-Rat (Rattus) NEIL1 Antikörper:

anti-Human NEIL1 Antikörper:

anti-Mouse (Murine) NEIL1 Antikörper:

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Am meisten referenzierte anti-NEIL1 Antikörper

  1. Human Polyclonal NEIL1 Primary Antibody für EIA, WB - ABIN953643 : Forsbring, Vik, Dalhus, Karlsen, Bergquist, Schrumpf, Bjørås, Boberg, Alseth: Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. in Carcinogenesis 2009 (PubMed)
    Zeige alle 5 Referenzen für 953643

  2. Human Polyclonal NEIL1 Primary Antibody für WB - ABIN653649 : Zhao, Krishnamurthy, Burrows, David: Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts. in Biochemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 653649

  3. Human Polyclonal NEIL1 Primary Antibody für IHC (p), IHC - ABIN268646 : Hazra, Izumi, Boldogh, Imhoff, Kow, Jaruga, Dizdaroglu, Mitra: Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

Weitere Antikörper gegen NEIL1 Interaktionspartner

Human Endonuclease VIII-Like 1 (NEIL1) Interaktionspartner

  1. identified the c-Jun N-terminal kinase 1 (JNK1 (zeige MAPK8 Antikörper)) as the kinase involved in the phosphorylation of NEIL1

  2. NEIL1 (rs5745908) is associated with Behcet's disease. The genetic association in NEIL1 is a predicted splice donor variant that may introduce a deleterious intron retention and result in a noncoding transcript variant.

  3. cellular NEIL1 is regulated by the UPP (zeige UPP1 Antikörper) mediated by the E3 ubiquitin ligases Mule (zeige HUWE1 Antikörper) and TRIM26 (zeige TRIM26 Antikörper), which plays a vital role in co-ordinating the cellular response to DNA damage.

  4. Nei (zeige PMCH Antikörper) Like DNA Glycosylase 1 (NEIL1) as a likely candidate gene due to its crucial role in B-cell activation (zeige BLNK Antikörper) and terminal differentiation.

  5. The abnormal expressions of NEIL1, NEIL2 (zeige NEIL2 Antikörper), and NEIL3 (zeige NEIL3 Antikörper) are involved in cancer through their association with the somatic mutation load.

  6. NEIL1 and NEIL2 (zeige NEIL2 Antikörper) cooperate with TDG (zeige TDG Antikörper) during base excision: TDG (zeige TDG Antikörper) occupies the abasic site and is displaced by NEILs, which further process the baseless sugar, thereby stimulating TDG (zeige TDG Antikörper)-substrate turnover.

  7. Findings suggesting that DNA glycosylase NEIL1 c.C844T is a defective allele.

  8. NEIL1 forms a multiprotein complex with DNA replication proteins via its C-terminal domain, allowing recruitment at the replication fork.

  9. Results show that YB-1 (zeige YBX1 Antikörper) interferes negatively with the AP site DNA cleavage activity of both APE1 (zeige APEX1 Antikörper) and NEIL1 for ssDNA and bubble structures.

  10. Rad9 (zeige RAD9A Antikörper) regulates base excision repair by controlling NEIL1 transcription.

Mouse (Murine) Endonuclease VIII-Like 1 (NEIL1) Interaktionspartner

  1. Collectively the data suggest that NEIL1-initiated repair of a subset of ROS (zeige ROS1 Antikörper)-induced DNA base lesions may be insufficient to prevent the initiation of inflammatory pathways during chronic UV exposure in mouse skin.

  2. Rad9 (zeige RAD9A Antikörper) regulates base excision repair by controlling Neil1 protein stability in mouse embryonic stem cells.

  3. Hypersensitivity to H2O2 caused by NEIL1 knockdown was more significant in S phase than in G1 phase, suggesting that NEIL1 has an important role during S phase.

  4. Data indicate that maternal folate depletion during pregnancy and high-fat feeding from weaning altered gene expression of Ogg1 (zeige OGG1 Antikörper), Neil1, Mutyh (zeige MUTYH Antikörper) and Xrcc1 (zeige XRCC1 Antikörper) in the brain of adult offspring.

  5. one role for Neil3 (zeige NEIL3 Antikörper) and NEIL1 is to repair DNA base damages in telomeres in vivo and that Neil3 (zeige NEIL3 Antikörper) and Neil1 may function in quadruplex-mediated cellular events, such as gene regulation via removal of damaged bases from quadruplex DNA.

  6. binds to the BRCT domain of PARP-1 (zeige PARP1 Antikörper)

  7. Neil1 contributes to germline and somatic Huntington's disease CAG repeat (zeige CELF3 Antikörper) expansion.

  8. Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice.

  9. NEIL1 deficiency results in an increased susceptibility to obesity and related complications potentially by lowering the threshold for tolerance of cellular oxidative stress in neil1(-/-) mice.

  10. NEIL1 is involved in nucleotide excision repair of(5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines, in addition to its function as a DNA glycosylase in base excision repair.

NEIL1 Antigen-Profil

Beschreibung des Gens

This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NEIL1

  • nei endonuclease VIII-like 1 (E. coli) (Neil1) Antikörper
  • nei endonuclease VIII-like 1 (E. coli) (NEIL1) Antikörper
  • 2810450N13Rik Antikörper
  • FPG1 Antikörper
  • hFPG1 Antikörper
  • Nei1 Antikörper

Bezeichner auf Proteinebene für NEIL1

endonuclease VIII-like 1 , DNA glycosylase/AP lyase Neil1 , DNA-(apurinic or apyrimidinic site) lyase Neil1 , NEH1 , endonuclease 8-like 1 , endonuclease VIII , nei homolog 1 , nei-like protein 1

GENE ID SPEZIES
367090 Rattus norvegicus
79661 Homo sapiens
72774 Mus musculus
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