NEIL1 Antikörper
Kurzübersicht für NEIL1 Antikörper (ABIN7073820)
Target
Alle NEIL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse NEIL1
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Applikationshinweise
- WB (M,R) 1:800-1:1600, IHC/IF (H,M,R) 1:1200-1:3000/1:300-1:600
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
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Andere Bezeichnung
- NEIL1
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Hintergrund
- NEIL1, also named as NEH1 and FPG1, belongs to the FPG family. It is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. NEIL1 acts as DNA glycosylase that recognizes and removes damaged bases. It has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. NEIL1 has marginal activity towards 8-oxoguanine. It has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.
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Molekulargewicht
- 44 kDa
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Gen-ID
- 72774
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NCBI Accession
- NP_082623
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UniProt
- Q8K4Q6
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Pathways
- DNA Reparatur
Target
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