NEIL1 Antikörper

Produktnummer ABIN7073820

Produktdetails anti-NEIL1 Antikörper

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEIL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse NEIL1

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:800-1:1600, IHC/IF (H,M,R) 1:1200-1:3000/1:300-1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu NEIL1

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Andere Bezeichnung: NEIL1 (NEIL1 Produkte)

Synonyme: FPG1 antikoerper, NEI1 antikoerper, hFPG1 antikoerper, 2810450N13Rik antikoerper, Nei1 antikoerper, nei-like DNA glycosylase 1 antikoerper, nei like DNA glycosylase 1 antikoerper, nei endonuclease VIII-like 1 (E. coli) antikoerper, Neil1 antikoerper, NEIL1 antikoerper

Hintergrund: NEIL1, also named as NEH1 and FPG1, belongs to the FPG family. It is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. NEIL1 acts as DNA glycosylase that recognizes and removes damaged bases. It has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. NEIL1 has marginal activity towards 8-oxoguanine. It has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.

Molekulargewicht: 44 kDa

Gen-ID: 72774

NCBI Accession: NP_082623

UniProt: Q8K4Q6

Pathways: DNA Reparatur