LIG3 Proteine (LIG3)

Bezeichnung:
Ligase III, DNA, ATP-Dependent Proteine (LIG3)
Auf www.antikoerper-online.de finden Sie aktuell 5 Ligase III, DNA, ATP-Dependent (LIG3) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LIG3 Antikörper (66) und LIG3 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 80 LIG3 Produkte verfügbar.
Synonyme:
An02g06890, AO090003000668, D11Wsu78e, DDBDRAFT_0218523, DDBDRAFT_0232266, DDB_0218523, DDB_0232266, LIG2, LIG3, orf36, wu:fb12c02, wu:fd10b03, wu:fm79b09
alle Proteine anzeigen Gen GeneID UniProt
LIG3 3980 P49916
Ratte LIG3 LIG3 303369  
LIG3 16882  

Weitere Synonyme anzeigen

LIG3 Proteine (LIG3) nach Spezies

Wählen Sie die gewünschte Spezies

Weitere Proteine zu LIG3 Interaktionspartnern

Human Ligase III, DNA, ATP-Dependent (LIG3) Interaktionspartner

  1. The g.29661G>A and g.29059C>T polymorphisms of LIG3 may play a role in the keratoconus and Fuchs endothelial corneal dystrophy pathogenesis and can be considered as markers in these diseases.

  2. A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 (zeige XRCC1 Proteine) gene on binding interaction of XRCC1 (zeige XRCC1 Proteine) protein with ligase III.

  3. In the context of tyrosine kinase (zeige TXK Proteine)-activated leukemias, c-MYC (zeige MYC Proteine) contributes to aberrant DNA repair through downstream targets LIG3 and PARP1 (zeige PARP1 Proteine) up-regulation.

  4. there is an absolute requirement for fully functional DNA ligase III (LIG3), but not ligase IV (LIG4 (zeige LIG4 Proteine)), to facilitate the escape from a telomere-driven crisis.

  5. Results show that overexpression of DNA ligase III in mitochondria improves mitochondrial base excision repair and enhances cell survival after oxidative stress.

  6. data confirm previous work showing that Lig3 is required to maintain mtDNA integrity and function, and highlight a new function of ATM (zeige ATM Proteine) in regulating DNA Lig3 stability and consequently mtDNA repair

  7. Human Mre11 (zeige MRE11A Proteine)/human Rad50 (zeige RAD50 Proteine)/Nbs1 (zeige NBN Proteine) and DNA ligase IIIalpha/XRCC1 (zeige XRCC1 Proteine) protein complexes act together in an alternative nonhomologous end joining pathway.

  8. Using our cohort of 480 breast cancer patients, we provide replicated evidence that a polymorphism near the LIG3 gene is associated with acute skin toxicity following radiotherapy.

  9. results establish a role for Lig3 in mitochondria, but distinguish it from its interacting protein Xrcc1 (zeige XRCC1 Proteine)

  10. The collective results support a "jackknife model" in which the ZnF loads ligase III onto nicked DNA and conformational changes deliver DNA into the active site.

Mouse (Murine) Ligase III, DNA, ATP-Dependent (LIG3) Interaktionspartner

  1. Results show that overexpression of DNA ligase III in mitochondria improves mitochondrial base excision repair and enhances cell survival after oxidative stress.

  2. data confirm previous work showing that Lig3 is required to maintain mtDNA integrity and function, and highlight a new function of ATM (zeige ATM Proteine) in regulating DNA Lig3 stability and consequently mtDNA repair

  3. Lig3 has an essential role in mtDNA maintenance but is dispensable for the viability of cultured cells

  4. data reveal that the critical biological role of Lig3 is to maintain mtDNA integrity and not Xrcc1 (zeige XRCC1 Proteine)-dependent DNA repair

  5. results establish a role for Lig3 in mitochondria, but distinguish it from its interacting protein Xrcc1 (zeige XRCC1 Proteine)

  6. Early embryonic lethality is due to targeted inactivation of DNA ligase III.

LIG3 Protein Überblick

Protein Überblick

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with LIG3

  • ligase III, DNA, ATP-dependent (lig3)
  • ligase III, DNA, ATP-dependent (LIG3)
  • DNA ligase III (orf36)
  • DNA ligase 3 (ANI_1_2644024)
  • DNA ligase 3 (AOR_1_1174154)
  • DNA ligase III (Bm1_22840)
  • BRCT domain-containing protein (lig3)
  • ligase III, DNA, ATP-dependent (Lig3)
  • An02g06890 Protein
  • AO090003000668 Protein
  • D11Wsu78e Protein
  • DDBDRAFT_0218523 Protein
  • DDBDRAFT_0232266 Protein
  • DDB_0218523 Protein
  • DDB_0232266 Protein
  • LIG2 Protein
  • LIG3 Protein
  • orf36 Protein
  • wu:fb12c02 Protein
  • wu:fd10b03 Protein
  • wu:fm79b09 Protein

Bezeichner auf Proteinebene für LIG3

ligase III, DNA, ATP-dependent , DNA ligase 3 , DNA ligase (ATP) 3 , DNA ligase 3 isoform alpha , DNA ligase III , DNA ligase 3-like , ligase II, DNA, ATP-dependent , polydeoxyribonucleotide synthase [ATP] 3

GENE ID SPEZIES
336509 Danio rerio
417530 Gallus gallus
454581 Pan troglodytes
491145 Canis lupus familiaris
514719 Bos taurus
549105 Xenopus (Silurana) tropicalis
715181 Macaca mulatta
955080 Heliothis zea virus 1
4979178 Aspergillus niger CBS 513.88
5991803 Aspergillus oryzae RIB40
6099475 Brugia malayi
8624245 Dictyostelium discoideum AX4
100071671 Equus caballus
100344941 Oryctolagus cuniculus
100405358 Callithrix jacchus
100455958 Pongo abelii
100464510 Ailuropoda melanoleuca
100634887 Amphimedon queenslandica
3980 Homo sapiens
303369 Rattus norvegicus
16882 Mus musculus
Ausgewählte Anbieter für LIG3 Proteine (LIG3)
Haben Sie etwas anderes gesucht?