LIG3 Produkte
(Ligase III, DNA, ATP-Dependent (LIG3))
Kategorien
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte LIG3 Kategorien
LIG3 Antikörper
High quality antibodies with extensive validation data.
LIG3 ELISA Kits
Reliable ELISA kits for a wide range of species.
LIG3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LIG3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN6143207
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN7257088
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN2855575
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LIG3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968293
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1130035
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LIG3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309403
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309402
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3134693
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LIG3 Produkten
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).: "PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF." in: Cell reports, Vol. 17, Issue 2, pp. 541-555, (2016) (PubMed).
: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).
: "DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair." in: Nucleic acids research, Vol. 43, Issue 2, pp. 875-92, (2015) (PubMed).
: "Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair." in: DNA repair, Vol. 16, pp. 44-53, (2014) (PubMed).
: "Age-dependent decline of DNA base excision repair activity in rat cortical neurons." in: Mechanisms of ageing and development, Vol. 133, Issue 4, pp. 186-94, (2012) (PubMed).
: "Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors." in: International journal of radiation oncology, biology, physics, Vol. 79, Issue 2, pp. 540-8, (2011) (PubMed).
: "Arsenicals affect base excision repair by several mechanisms." in: Mutation research, Vol. 715, Issue 1-2, pp. 32-41, (2011) (PubMed).
: "Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy." in: Blood, Vol. 116, Issue 24, pp. 5298-305, (2010) (PubMed).
: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).
Synonyme und alternative Namen zu LIG3
DNA ligase III (orf36), BRCT domain-containing protein (lig3), DNA ligase 3 (LIG3), ligase III, DNA, ATP-dependent (lig3), DNA ligase 3 (Lig3), DNA ligase III (Bm1_22840), ligase III, DNA, ATP-dependent (Lig3), DNA ligase 3 (ANI_1_2644024), DNA ligase 3 (AOR_1_1174154), DNA ligase 3 (LOC100634887), ligase III, DNA, ATP-dependent L homeolog (lig3.L), An02g06890, AO090003000668, D11Wsu78e, DDBDRAFT_0218523, DDBDRAFT_0232266, DDB_0218523, DDB_0232266, LIG2, LIG3, lig3, orf36, wu:fb12c02, wu:fd10b03, wu:fm79b09Bezeichner auf Proteinebene für LIG3
- DNA ligase III
- ligase III, DNA, ATP-dependent
- DNA ligase (ATP) 3
- DNA ligase 3
- ligase II, DNA, ATP-dependent
- polydeoxyribonucleotide synthase [ATP] 3
- DNA ligase 3 isoform alpha
- DNA ligase 3-like
- DNA ligase III isoform alpha
- ligase III, DNA, ATP-dependent L homeolog
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