anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) Antikörper

Bezeichnung:
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 Antikörper (ERCC4)
Auf www.antikoerper-online.de finden Sie aktuell 117 Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 Kits (4) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 128 Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 Produkte verfügbar.
Synonyme:
AI606920, ERCC4, ERCC11, FANCQ, fi03a05, LOC100231158, RAD1, RGD1560340, wu:fi03a05, Xpf, zgc:63468
Alle Antikörper anzeigen Gen GeneID UniProt
ERCC4 360465  
ERCC4 2072 Q92889
ERCC4 50505 Q9QZD4

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Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 Antikörper

  1. Human Polyclonal ERCC4 Primary Antibody für ELISA, ICC - ABIN253150 : Earley, Turchi: Interrogation of nucleotide excision repair capacity: impact on platinum-based cancer therapy. in Antioxidants & redox signaling 2011 (PubMed)
    Zeige alle 2 Referenzen für 253150

  2. Human Monoclonal ERCC4 Primary Antibody für WB - ABIN180455 : Boulikas: Xeroderma pigmentosum and molecular cloning of DNA repair genes. in Anticancer research 1996 (PubMed)

  3. Human Monoclonal ERCC4 Primary Antibody für ELISA, ICC - ABIN451725 : Paul, Nagano, Robaire: Aging results in differential regulation of DNA repair pathways in pachytene spermatocytes in the Brown Norway rat. in Biology of reproduction 2011 (PubMed)

Weitere Antikörper gegen Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 Interaktionspartner

Xenopus laevis Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) Interaktionspartner

  1. These data support a model in which the interstrand crosslink repair-specific function of XPF-ERCC1 (zeige ERCC1 Antikörper) is dependent on recruitment, positioning and substrate recognition.

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) Interaktionspartner

  1. ERCC1 (zeige ERCC1 Antikörper) was not detectable in the nucleus of the XPF knockout cells indicating the necessity of a functional XPF/ERCC1 (zeige ERCC1 Antikörper) heterodimer to allow ERCC1 (zeige ERCC1 Antikörper) to enter the nucleus.

  2. Strikingly, the addition of the single-stranded DNA (ssDNA)-binding replication protein A (RPA) selectively restores XPF-ERCC1 endonuclease activity on this structure. The 5'-3' exonuclease SNM1A can load from the XPF-ERCC1-RPA-induced incisions and digest past the crosslink to quantitatively complete the unhooking reaction.

  3. Based on structural models, NMR titrations, DNA-binding studies, site-directed mutagenesis, charge distribution, and sequence conservation, we propose that the HhH (zeige SLC25A15 Antikörper) domain of ERCC1 (zeige ERCC1 Antikörper) binds to dsDNA upstream of the damage, and XPF binds to the non-damaged strand within a repair bubble

  4. silenced XPF significantly increased the sensitivity and survival following treatment with cisplatin in xenograft mice bearing renal cell tumor.

  5. Polymorphisms in XPF gene is associated with gastrointestinal stromal tumours.

  6. inherited abnormalities in DNA repair pathway related to XPF 30028C and TP53 (zeige TP53 Antikörper) Arg72Pro polymorphisms act as prognostic factors for progression free survival and overall survival of cutaneous melanoma patients.

  7. Based on these results, we conclude that the XPF gene polymorphism Ser835Ser may be associated with a decreased risk of colorectal cancer.

  8. Polymorphisms of ERCC4 gene are associated with HPV-positive cervical cancer.

  9. Helicobacter Pylori introduces double-stranded DNA breaks by the nucleotide excision repair endonucleases XPF and XPG (zeige ERCC5 Antikörper), which, together with RelA (zeige NFkBP65 Antikörper), are recruited to chromatin in a highly coordinated, type IV secretion system-dependent manner.

  10. SLX4 (FANCP (zeige BTBD12 Antikörper)) and XPF (FANCQ) proteins interact with each other and play a vital role in the Fanconi anemia (zeige PALB2 Antikörper) (FA) DNA repair pathway.

Mouse (Murine) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) Interaktionspartner

  1. these results establish USP45 as a new regulator of XPF-ERCC1 (zeige ERCC1 Antikörper) crucial for efficient DNA repair

  2. SLX4 (zeige BTBD12 Antikörper) is a tumor suppressor, which activates XPF-ERCC1 (zeige ERCC1 Antikörper) nuclease (zeige DCLRE1C Antikörper) specificity in DNA crosslink repair.

  3. Data reveal an unanticipated involvement of the ERCC1 (zeige ERCC1 Antikörper)/XPF NER (zeige NR1H2 Antikörper) endonuclease in the regulation of telomere integrity.

  4. mitomycin C triggered sister chromatid exchanges in wild-type cells but chromatid fusions in Ercc1 (zeige ERCC1 Antikörper)(-/-) and Xpf mutant cells, indicating that in their absence, repair of double-strand breaks(DSBs)is prevented.

  5. In mice with overexpressed TRF2 (zeige TERF2 Antikörper), telomere loss is mediated by Xpf.

  6. These data support the conclusion that, as in yeast, ERCC1 (zeige ERCC1 Antikörper)-XPF facilitates double-strand breaks repair via an end-joining mechanism that is Ku86 (zeige XRCC5 Antikörper) independent.

Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Alternative names and synonyms associated with Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4)

  • excision repair cross-complementing rodent repair deficiency, complementation group 4 (ercc4) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 4-like 1 (Ercc4l1) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 4 (XPF) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 4 (LOC100231158) Antikörper
  • excision repair cross-complementing rodent repair deficiency, complementation group 4 (Ercc4) Antikörper
  • AI606920 Antikörper
  • ERCC4 Antikörper
  • ERCC11 Antikörper
  • FANCQ Antikörper
  • fi03a05 Antikörper
  • LOC100231158 Antikörper
  • RAD1 Antikörper
  • RGD1560340 Antikörper
  • wu:fi03a05 Antikörper
  • Xpf Antikörper
  • zgc:63468 Antikörper

Bezeichner auf Proteinebene für ERCC4

DNA repair endonuclease XPF , XPF , excision repair cross-complementing rodent repair deficiency, complementation group 4 , DNA repair endonuclease XPF-like , DNA excision repair protein ERCC-4 , DNA repair protein complementing XP-F cells , excision-repair, complementing defective, in Chinese hamster , xeroderma pigmentosum group F-complementing protein , xeroderma pigmentosum, complementation group F , DNA repair endonuclease subunit , Ercc4 protein-like

GENE ID SPEZIES
327322 Danio rerio
360465 Rattus norvegicus
416420 Gallus gallus
446411 Xenopus laevis
453935 Pan troglodytes
516371 Bos taurus
712641 Macaca mulatta
7198823 Phaeodactylum tricornutum CCAP 1055/1
100024202 Monodelphis domestica
100050812 Equus caballus
100145552 Xenopus (Silurana) tropicalis
100231158 Taeniopygia guttata
100350642 Oryctolagus cuniculus
100395516 Callithrix jacchus
100454987 Pongo abelii
100470341 Ailuropoda melanoleuca
100516427 Sus scrofa
100542086 Meleagris gallopavo
2072 Homo sapiens
50505 Mus musculus
479842 Canis lupus familiaris
304719 Rattus norvegicus
100689044 Cricetulus griseus
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