anti-NLRP3 (NLRP3) Antikörper

Bezeichnung:
anti-NLR Family, Pyrin Domain Containing 3 Antikörper (NLRP3)
Auf www.antikoerper-online.de finden Sie aktuell 222 NLR Family, Pyrin Domain Containing 3 (NLRP3) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NLRP3 Kits (11) und NLRP3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 251 NLRP3 Produkte verfügbar.
Synonyme:
AGTAVPRL, AII, AII/AVP, AVP, C1orf7, Cias1, CLR1.1, FCAS, FCU, Mmig1, MWS, NALP3, Pypaf1
Alle Antikörper anzeigen Gen GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
NLRP3 287362  

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Meistgesuchte Reaktivitäten zu anti-NLRP3 (NLRP3) Antikörper

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anti-Human NLRP3 Antikörper:

anti-Mouse (Murine) NLRP3 Antikörper:

anti-Rat (Rattus) NLRP3 Antikörper:

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Am meisten referenzierte anti-NLRP3 Antikörper

  1. Human Polyclonal NLRP3 Primary Antibody für IF (p), IHC (p) - ABIN1386361 : Zendedel, Johann, Mehrabi, Joghataei, Hassanzadeh, Kipp, Beyer: Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. in Molecular neurobiology 2015 (PubMed)
    Zeige alle 7 Referenzen für 1386361

  2. Human Monoclonal NLRP3 Primary Antibody für FACS, ICC - ABIN4898963 : Hu, Zhang, Wang, Mao, Lv, Yuan, Huang, Ding, Xie, Liu: Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. in Cell death & disease 2016 (PubMed)
    Zeige alle 6 Referenzen für 4898963

  3. Human Polyclonal NLRP3 Primary Antibody für IHC, IHC (p) - ABIN4340115 : Abdul-Sater, Koo, Häcker, Ojcius: Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 5 Referenzen für 4340115

  4. Human Monoclonal NLRP3 Primary Antibody für IHC, IHC (fro) - ABIN4340117 : Shio, Tiemi Shio, Eisenbarth, Savaria, Vinet, Bellemare, Harder, Sutterwala, Bohle, Descoteaux, Flavell, Olivier: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. in PLoS pathogens 2009 (PubMed)
    Zeige alle 3 Referenzen für 4340117

  5. Human Polyclonal NLRP3 Primary Antibody für IHC (p), WB - ABIN652504 : Jhang, Lu, Ho, Cheng, Yen: Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation. in Journal of agricultural and food chemistry 2015 (PubMed)
    Zeige alle 2 Referenzen für 652504

  6. Human Polyclonal NLRP3 Primary Antibody für IHC (p), IHC - ABIN251577 : Wei, Chen, James, Stone, Chamley: IL-1 beta but not the NALP3 inflammasome is an important determinant of endothelial cell responses to necrotic/dangerous trophoblastic debris. in Placenta 2015 (PubMed)
    Zeige alle 2 Referenzen für 251577

  7. Human Polyclonal NLRP3 Primary Antibody für ELISA, IHC (p) - ABIN249728 : Hoffman, Mueller, Broide, Wanderer, Kolodner: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. in Nature genetics 2001 (PubMed)

  8. Human Monoclonal NLRP3 Primary Antibody für WB - ABIN4340119 : Dolunay, Senol, Temiz-Resitoglu, Guden, Sari, Sahan-Firat, Tunctan: Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms. in Inflammation 2016 (PubMed)

  9. Human Polyclonal NLRP3 Primary Antibody für EIA, WB - ABIN453768 : Feldmann, Prieur, Quartier, Berquin, Certain, Cortis, Teillac-Hamel, Fischer, de Saint Basile: Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. in American journal of human genetics 2002 (PubMed)

Weitere Antikörper gegen NLRP3 Interaktionspartner

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) Interaktionspartner

  1. defective ribosomal products in blebs induced IL-1beta (zeige IL1B Antikörper) release from peripheral blood mononuclear cells or THP-1 (zeige GLI2 Antikörper) cells without lipopolysaccharide priming, but required the core machinery of NLRP3 inflammasomes.

  2. besides its role in the inhibition of the NF-kappaB (zeige NFKB1 Antikörper) pathway, NLRC3 (zeige NLRC3 Antikörper) interferes with the assembly and activity of the NALP3 inflammasome complex by competing with ASC (zeige PYCARD Antikörper) for pro-caspase-1 (zeige CASP1 Antikörper) binding

  3. uropathogenic E. coli use the multifunctional virulence factor TcpC to induce NLRP3 inflammasome expression, and attenuate innate immune responses in the urinary tract

  4. miR (zeige MLXIP Antikörper)-223 limits intestinal inflammation by constraining the nlrp3 inflammasome.

  5. These data suggest that targeting NLRP3 holds the promise for the immunotherapy of pancreatic ductal adenocarcinoma.

  6. EAE induced by weak activation of innate immunity requires the NLRP3 inflammasome and is sensitive to interferon-beta (zeige IFNB1 Antikörper) treatment

  7. this is the first report describing the existence and function of the nucleotide-binding oligomerization domain-like receptor protein 3 (zeige HSPB3 Antikörper) inflammasome in human dendritic cells.

  8. PTPN22 (zeige PTPN22 Antikörper) deficiency resulted in pronounced colitis, increased NLRP3 phosphorylation, but reduced levels of mature IL-1beta (zeige IL1B Antikörper).

  9. The authors further demonstrated that the upregulation of sterol regulatory element-binding protein (zeige CNBP Antikörper) (SREBP)-1c (zeige SREBF1 Antikörper) by activation of the Akt (zeige AKT1 Antikörper) and p70S6K (zeige RPS6KB1 Antikörper) pathways is critical for high-glucose-treated Porphyromonas gingivalis-induced NLRP3 expression.

  10. LFG (zeige FAIM2 Antikörper)-500 markedly suppresses epithelial mesenchymal transformation by inhibiting the NLRP3 inflammasome in the inflammatory microenvironment.

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) Interaktionspartner

  1. proposed that TLR9 (zeige TLR9 Antikörper) regulates the NF-kappaB (zeige NFKB1 Antikörper)-NLRP3-IL-1beta (zeige IL1B Antikörper) pathway negatively in Salmonella-induced NKG2D (zeige KLRK1 Antikörper)-mediated intestinal inflammation and plays a critical role in defense against S. typhimurium infection and in the protection of intestinal integrity.

  2. The results suggest that mitochondrial function is required somewhat specifically for ATP-induced NLRP3 inflammasome activation.

  3. uropathogenic E. coli use the multifunctional virulence factor TcpC to induce NLRP3 inflammasome expression, and attenuate innate immune responses in the urinary tract

  4. NLRP3(-/-) mice had reduced defects in echo/Doppler parameters in heart after cecal ligation and puncture

  5. this study shows that plant lectins can act as an exogenous "danger signal" that can activate the NLRP3 inflammasome and suggest that dietary lectins might promote inflammatory diseases via the NLRP3 inflammasome

  6. miR (zeige MLXIP Antikörper)-223 limits intestinal inflammation by constraining the nlrp3 inflammasome.

  7. NLRP3 is a novel target of the YopM protein.

  8. These results propose that the balance between kinases and phosphatases acting on the NLRP3 pyrin (zeige MEFV Antikörper) domain is critical for NLRP3 activation.

  9. These data suggest that targeting NLRP3 holds the promise for the immunotherapy of pancreatic ductal adenocarcinoma.

  10. this study shows that oxidized low-density lipoprotein immune complexes increased expression of inflammasome-related gene Nlrp3

NLRP3 Antigen-Profil

Beschreibung des Gens

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Alternative names and synonyms associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) Antikörper
  • NLR family, pyrin domain containing 3 (LOC100351623) Antikörper
  • NLR family, pyrin domain containing 3 (nlrp3) Antikörper
  • NLR family, pyrin domain containing 3 (Nlrp3) Antikörper
  • AGTAVPRL Antikörper
  • AII Antikörper
  • AII/AVP Antikörper
  • AVP Antikörper
  • C1orf7 Antikörper
  • Cias1 Antikörper
  • CLR1.1 Antikörper
  • FCAS Antikörper
  • FCU Antikörper
  • Mmig1 Antikörper
  • MWS Antikörper
  • NALP3 Antikörper
  • Pypaf1 Antikörper

Bezeichner auf Proteinebene für NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

GENE ID SPEZIES
423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
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