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anti-Mouse (Murine) HK3 Antikörper:
anti-Human HK3 Antikörper:
anti-Rat (Rattus) HK3 Antikörper:
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Human Polyclonal HK3 Primary Antibody für WB - ABIN392754
Palmieri, Fitzgerald, Shreeve, Hua, Bronder, Weil, Davis, Stark, Merino, Kurek, Mehdorn, Davis, Steinberg, Meltzer, Aldape, Steeg: Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. in Molecular cancer research : MCR 2009
Human Polyclonal HK3 Primary Antibody für IHC (p), WB - ABIN392753
Furuta, Nishi, Le Beau, Fernald, Yano, Bell: Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. in Genomics 1997
Show all 4 Pubmed References
plastid HXK enzyme activities, location, function in signal transduction, and cross talk to plastid GUN1 protein (a (zeige GPR153 Antikörper) key signaling factor) were investigated. pHXK may be a node of convergence for sugar-mediated and PGE (zeige LIPF Antikörper)-derived signals.
Hexokinase expression is highly enriched in neurons compared to astrocytes.
HK3 expression is significantly upregulated in human masticatory mucosa during wound healing
HK1 (zeige KCNA4 Antikörper) and HK2 (zeige HK2 Antikörper) expression alterations were detected, that could be explained by common deregulation mechanisms of these genes in colorectal tumors. The HK3 expression level was significantly increased in 60% of samples.
Through glycolysis and arachidonic acid metabolism, HK3 and PTGS2 (zeige PTGS2 Antikörper) might play important roles in pediatric ALL and its prognosis, and thus, might be potential targets for therapeutic intervention to suppress pediatric ALL.
Altogether, our data provide an explanation for low HK3 and KLF5 (zeige KLF5 Antikörper) expression in particular AML (zeige RUNX1 Antikörper) subtype and establish these genes as novel CEBPA (zeige CEBPA Antikörper) targets during neutrophil differentiation.
HK3 is: (1) directly activated by PU.1, (2) repressed by PML (zeige PML Antikörper)-RARA (zeige RARA Antikörper), and (3) functionally involved in neutrophil differentiation and cell viability of acute promyelocytic leukemia (zeige PML Antikörper) cells.
Data demonstrated that in addition to galectin-3 (zeige LGALS3 Antikörper), HK III and cyclin A (zeige CCNA2 Antikörper) profiles could be important biomarkers in predicting malignancy in follicular thyroid nodules.
Data show that HKIII exerts protective effects against oxidative stress, perhaps by increasing ATP levels, reducing oxidant-induced ROS (zeige ROS1 Antikörper) production, preserving mitochondrial membrane potential, and increasing mitochondrial biogenesis.
The expression pattern of HK3 is reported in newly diagnosed esophageal adenocarcinoma by means of immunohistochemistry.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.
hexokinase 3 (white cell)
, hexokinase type III
, ATP:D-hexose 6-phosphotransferase
, HK III