anti-Maus FASL Antikörper für Mass Cytometry

Recommended FASL Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • Fas ligand (TNF superfamily, member 6)
  • Fas (TNF receptor superfamily, member 6)
  • fas ligand
  • faslg
  • FAS
  • FASLG
  • fas
  • LOC100344073
  • Fasl
  • Faslg
Reaktivität
Maus
404
173
89
36
7
5
5
3
3
2
1
1
Wirt
Hamster
242
175
48
32
29
8
1
Klonalität
Monoklonal
Konjugat
Dieser FASL Antikörper ist unkonjugiert
44
30
26
11
11
8
8
8
8
7
7
7
7
7
6
5
5
4
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Mass Cytometry (CyTOF), Immunohistochemistry (IHC)
298
244
111
96
80
75
38
34
28
28
13
12
10
10
5
4
3
2
2
2
1
1
1
1
1
1
1
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Bilder

Produktnummer ABIN2665563
310,59 €
Zzgl. Versandkosten 20,00 € und MWSt

anti-FASL Antikörper für Mass Cytometry mit den meisten Publikationen

Ähnliche anti-FASL Antikörper

Applikation / Reaktivität Maus
Blocking Reagent (BR) 3 Antikörper
ELISA 10 Antikörper
Flow Cytometry (FACS) 103 Antikörper
Functional Studies (Func) 9 Antikörper
Immunochromatography (IC) 3 Antikörper
Immunocytochemistry (ICC) 9 Antikörper
Immunofluorescence (IF) 6 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 1 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper
Immunohistochemistry (IHC) 28 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antikörper
Immunoprecipitation (IP) 6 Antikörper
Mass Cytometry (CyTOF) 1 Antikörper
Neutralization (Neut) 4 Antikörper
Western Blotting (WB) 58 Antikörper

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper
Reaktivität Maus
(404), (173), (89), (36), (7), (5), (5), (3), (3), (2), (1), (1)
Wirt Hamster
(242), (175), (48), (32), (29), (8), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser FASL Antikörper ist unkonjugiert
(44), (30), (26), (11), (11), (8), (8), (8), (8), (7), (7), (7), (7), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Mass Cytometry (CyTOF), Immunohistochemistry (IHC)
(298), (244), (111), (96), (80), (75), (38), (34), (28), (28), (13), (12), (10), (10), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FASL Antikörper

Target Details FASL Anwendungsinformationen Handhabung ProductDetails: References for anti-FASL antibody (ABIN2665563) Bilder
Marke LEAF™
Reinigung The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterilität 0.2 μm filtered
Endotoxin-Niveau

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Klon MFL3
Isotyp IgG

Target Details FASL

Produktdetails anti-FASL Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-FASL antibody (ABIN2665563) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD178 (FASL Antibody Abstract)
Hintergrund CD178 is a 40 kD member of the TNF/NGF superfamily also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. Cell surface CD178 is expressed on activated T cells and in testis and eye. CD178 is upregulated in activated T cells upon TCR re-engagement and has been shown to induce autocrine and paracrine T cell death. CD178 expression in the eye and testis has been shown to participate in immune privilege at these sites. CD178 can be cleaved from the surface by metalloproteases, and "soluble" CD178 may block the activities of membrane-bound CD178. CD178 binds to CD95 (Fas) to induce apoptotic cell death implicated in the maintenance of peripheral tolerance. CD178/CD95 interactions have also been implicated in the proliferation of CD8+ cells and neutrophil extravasation, chemotaxis, and survival. The MFL3 antibody recognizes CD178 in a wide array of mouse strains and has been reported to block CD178/CD95 induced apoptosis.
Pathways Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-FASL Antikörper Target Details FASL Handhabung ProductDetails: References for anti-FASL antibody (ABIN2665563) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen ProductDetails: References for anti-FASL antibody (ABIN2665563) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Konservierungsmittel Azide free
Handhabung This LEAF™ solution contains no preservative, handle under aseptic conditions
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-FASL antibody (ABIN2665563)

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Nakahira, Nakanishi: "Requirement of GATA-binding protein 3 for II13 gene expression in IL-18-stimulated Th1 cells." in: International immunology, Vol. 23, Issue 12, pp. 761-72, 2011

Oida, Weiner: "Murine CD4 T cells produce a new form of TGF-β as measured by a newly developed TGF-β bioassay." in: PLoS ONE, Vol. 6, Issue 4, pp. e18365, 2011

Lundqvist, Yokoyama, Smith, Berg, Childs: "Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells." in: Blood, Vol. 113, Issue 24, pp. 6120-7, 2009

Park, Jung, Park, Lee, Choi, Choi: "Interaction of Fas ligand and Fas expressed on osteoclast precursors increases osteoclastogenesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 11, pp. 7193-201, 2005

Seko, Kayagaki, Seino, Yagita, Okumura, Nagai: "Role of Fas/FasL pathway in the activation of infiltrating cells in murine acute myocarditis caused by Coxsackievirus B3." in: Journal of the American College of Cardiology, Vol. 39, Issue 8, pp. 1399-403, 2002

Hill, Ouhtit, Loughlin, Kripke, Ananthaswamy, Owen-Schaub: "Fas ligand: a sensor for DNA damage critical in skin cancer etiology." in: Science (New York, N.Y.), Vol. 285, Issue 5429, pp. 898-900, 1999

Fuller, Ravichandran, Braciale: "Phosphatidylinositol 3-kinase-dependent and -independent cytolytic effector functions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 11, pp. 6337-40, 1999

Kayagaki, Yamaguchi, Nagao, Matsuo, Maeda, Okumura, Yagita: "Polymorphism of murine Fas ligand that affects the biological activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3914-9, 1997

Takahashi, Tanaka, Brannan, Jenkins, Copeland, Suda, Nagata: "Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand." in: Cell, Vol. 76, Issue 6, pp. 969-76, 1994

Bilder

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Handhabung ProductDetails: References for anti-FASL antibody (ABIN2665563) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-FASL Antikörper (Fas Ligand (TNF Superfamily, Member 6)) (ABIN2665563) anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody