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anti-Human BIRC5 Antikörper:
anti-Mouse (Murine) BIRC5 Antikörper:
anti-Rat (Rattus) BIRC5 Antikörper:
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Mouse (Murine) Polyclonal BIRC5 Primary Antibody für WB - ABIN3043511
Li, Zhao, Lu, Li, Yang, Wu, Liu: Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation. in PLoS ONE 2014
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Human Polyclonal BIRC5 Primary Antibody für WB - ABIN3043195
Zhang, Lu, Hou, Hu, Wang: The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells. in Tumour biology 2014
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Human Polyclonal BIRC5 Primary Antibody für IHC (p), ELISA - ABIN3042792
Cai, Liu, Zhao, Wan, Hu, Zhou, Chen: Expressions of survivin and vascular endothelial growth factor in a Murine model of proliferative retinopathy. in International journal of ophthalmology 2012
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Human Monoclonal BIRC5 Primary Antibody für FACS - ABIN4895256
Mera, Magnusson, Tarkowski, Bokarewa: Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern. in Journal of leukocyte biology 2007
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Human Monoclonal BIRC5 Primary Antibody für IF, IP - ABIN559893
Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. in Molecular biology of the cell 2010
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Human Polyclonal BIRC5 Primary Antibody für CyTOF, FACS - ABIN4900855
Charalambous, Oks, Nchinda, Yamazaki, Steinman: Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Human Monoclonal BIRC5 Primary Antibody für FACS - ABIN4895255
Perabo, Frössler, Landwehrs, Schmidt, von Rücker, Wirger, Müller: Indirubin-3'-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer. in Anticancer research 2006
Human Monoclonal BIRC5 Primary Antibody für CyTOF, FACS - ABIN4898957
Schneider, Costa, Legrand, Bigot, Lecleire, Grassi, Vannier, Vasse: In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia. in Leukemia research 2010
ablation of Glut1 (zeige SLC2A1 Antikörper) attenuated apoptosis and increased drug resistance via upregulation of p-Akt (zeige AKT1 Antikörper)/p-GSK-3beta (zeige GSK3b Antikörper) (Ser9)/beta-catenin (zeige CTNNB1 Antikörper)/survivin.
Nuclear survivin expression correlates with endoglin (zeige ENG Antikörper)-assessed microvascularisation in laryngeal squamous cell carcinoma.
survivin expression modes and YAP (zeige YAP1 Antikörper) localization (Hippo pathway activation modes) were not correlated with survival. In addition, we confirmed that survivin small interference RNA (siRNA) transfection and YM155, an anti-survivin drug, elicited decreased nuclear survivin expression and cell proliferation in ISO-HAS-B cells which expressed survivin consistently
Survivin expression in lung squamous cell carcinoma was increased compared to normal tissue, and was unaffected by methylation status of the surviving gene.
Survivin gene promoter methylation was more frequent in gastric cancer patients than in controls.
These findings uncover the significance of Merlin (zeige NF2 Antikörper) protein expression and Survivin labeling index as prognosticators for poor clinical outcome in two independent Malignant pleural mesothelioma cohorts.
circulating Survivin in prostate cancer patients was higher compared to controls, with the highest levels in African-American (AA) patients. AA patients with prostate cancer contained higher amounts of extracellular vesicles (EVs) in their plasma and sera than European-American (EA) patients. EVs from AA patients with prostate cancer contained higher amounts of Survivin, XIAP (zeige XIAP Antikörper) and cIAP-2 (zeige BIRC3 Antikörper) than EVs from EA patients.
results indicate that survivin is of prognostic signi fi cance in patients with renal cell carcinoma (zeige MOK Antikörper)
The aim of this study was to compare the prognostic value of the histopathological grading and the conventional biomarker MIB-1 with expression of the anti-apoptotic protein survivin to see if this biomarker could complement recurrence prediction.
Data suggest that the first 22 bp of exon 3 in BIRC5 contain cis (zeige CISH Antikörper)-acting elements that enhance the exclusion of exon 3 to generate the survivin DEx3 mRNA isoform via exclusion/deletion of exon 3; Sam68 (zeige KHDRBS1 Antikörper) is a possible trans-acting factor that binds to this cis (zeige CISH Antikörper)-acting element and regulates exon 3 splicing. (BIRC5/survivin = baculoviral IAP repeat containing 5; Sam68 (zeige KHDRBS1 Antikörper) = GAP-associated tyrosine phosphoprotein p62 (zeige KHDRBS1 Antikörper))
Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.
Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.
Report survivin expression in the normal pancreas.
HDL (zeige HSD11B1 Antikörper)-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 (zeige STAT3 Antikörper) activity and survivin expression.
Survivin also attenuates DNA damage related to PARP (zeige PARP1 Antikörper) activation and inhibits TNFalpha (zeige TNF Antikörper)-induced lipolysis, suggesting that Survivin may facilitate adipocyte maintenance in response to inflammatory stimuli.
The study assigns a new meiotic function to Cullin9 and reveals that it prevents mouse eggs from aneuploidy by regulating microtubule dynamics via survivin.
this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin
Survivin was regulated by TGF-beta (zeige TGFB1 Antikörper) and was found to be highly expressed during mucosal healing following intestinal inflammation
Survivin is a key regulator of gut (zeige GUSB Antikörper) tissue integrity by regulating epithelial homeostasis in the stem cell niche.
TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (zeige WNT2 Antikörper) in CPCs to mediate cardioprotection and improve cardiac function.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (zeige CYP11A1 Antikörper)) cancer stem cell formation and cancer SCC (zeige CYP11A1 Antikörper) development.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (zeige BCL2 Antikörper) and ki67 (zeige MKI67 Antikörper).
survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing 5 (survivin)
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5 (survivin)-like
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor 4
, survivin variant 3 alpha