eIF4EBP1 Antikörper

Produktnummer ABIN969467

Produktdetails anti-eIF4EBP1 Antikörper

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser eIF4EBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of 4EBP1 expressed in E. coli.

Klon: 11G12C11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu eIF4EBP1

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Andere Bezeichnung: 4E-BP1 (EIF4EBP1 Produkte)

Synonyme: 4E-BP1 antikoerper, 4EBP1 antikoerper, BP-1 antikoerper, PHAS-I antikoerper, 4e-bp1 antikoerper, AA959816 antikoerper, 153432_at antikoerper, 43-BP antikoerper, 4E-BP antikoerper, 4EBP antikoerper, 4e-bp antikoerper, 4eBP antikoerper, 4ebp antikoerper, BcDNA.HL08053 antikoerper, BcDNA:HL08053 antikoerper, CG8846 antikoerper, CT8705 antikoerper, Dm 4E-BP antikoerper, Dmel\\CG8846 antikoerper, Phas1 antikoerper, Thor/EIF4EBP antikoerper, anon-WO0172774.158 antikoerper, d4E-BP antikoerper, d4E-BP1 antikoerper, d4EBP antikoerper, d4e-bp antikoerper, d4eBP antikoerper, dthor antikoerper, eIF4E-BP antikoerper, l(2)06270 antikoerper, l(2)k07736 antikoerper, l(2)k13517 antikoerper, pp20 antikoerper, thor antikoerper, EIF4EBP1 antikoerper, fc04h09 antikoerper, wu:fc04h09 antikoerper, zgc:64137 antikoerper, eukaryotic translation initiation factor 4E binding protein 1 antikoerper, CG8846 gene product from transcript CG8846-RA antikoerper, EIF4EBP1 antikoerper, Eif4ebp1 antikoerper, Thor antikoerper, eif4ebp1 antikoerper

Hintergrund:

Description: 4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13 kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24 kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.

Aliases: BP-1, 4EBP1, 4E-BP1, PHAS-I, MGC4316, EIF4EBP1

Gen-ID: 1978

HGNC: 1978

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling