TUBB3 Antikörper

Produktnummer ABIN967213

Produktdetails anti-TUBB3 Antikörper

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human TUBB3 expressed in E. Coli.

Klon: 2E9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-TUBB3 Antikörper (ABIN967213)

Katsetos, Dráberová, Smejkalová, Reddy, Bertrand, de Chadarévian, Legido, Nissanov, Baas, Dráber: "Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells." in: Neurochemical research, Vol. 32, Issue 8, pp. 1387-98, (2007) (PubMed).

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: TUBB3 (TUBB3 Produkte)

Synonyme: CDCBM antikoerper, CFEOM3A antikoerper, TUBB4 antikoerper, beta-4 antikoerper, TUBB3 antikoerper, 3200002H15Rik antikoerper, M(beta)3 antikoerper, M(beta)6 antikoerper, tubb3 antikoerper, tubulin beta 3 class III antikoerper, tubulin, beta 3 class III antikoerper, tubulin beta 3 class III L homeolog antikoerper, beta-tubulin 3 antikoerper, tubulin beta-3 chain antikoerper, beta tubulin 3 antikoerper, TUBB3 antikoerper, Tubb3 antikoerper, tubb3 antikoerper, tubb3.L antikoerper, LOC100581245 antikoerper, tub3 antikoerper

Hintergrund: Tubulin, beta 3, also known as TUBB3. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The beta-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III beta-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III beta-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.
Synonyms: tubulin, beta 3, MC1R, TUBB4

Molekulargewicht: 50kDa

Gen-ID: 10381

Pathways: Microtubule Dynamics, M Phase