MUC1 Antikörper (DTRP (Asp-Thr-Arg-Pro))
-
- Target Alle MUC1 Antikörper anzeigen
- MUC1 (Mucin 1 (MUC1))
-
Bindungsspezifität
- DTRP (Asp-Thr-Arg-Pro)
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser MUC1 Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Aufreinigung
- Concentrated.
- Immunogen
- Human Milk Fat Globule Membranes
- Klon
- B24-1 (GP1-4)
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MUC1 Primärantikörper
-
-
- Applikationshinweise
-
Immunohistochemistry: (Paraffin/Frozen): 1:50.
Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory. - Kommentare
-
Cellular Localization: Cell Membrane, Cytoplasmic.
Recommended Positive Control: Breast Carcinoma - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.3 mg/ml.
- Buffer
- 20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
-
-
Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).
: "
-
Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
-
- Target
- MUC1 (Mucin 1 (MUC1))
- Andere Bezeichnung
- EMA (MUC1 Produkte)
- Synonyme
- CA 15-3 antikoerper, CD227 antikoerper, EMA antikoerper, H23AG antikoerper, KL-6 antikoerper, MAM6 antikoerper, MCKD1 antikoerper, MUC-1 antikoerper, MUC-1/SEC antikoerper, MUC-1/X antikoerper, MUC1/ZD antikoerper, PEM antikoerper, PEMT antikoerper, PUM antikoerper, Muc-1 antikoerper, mucin 1, cell surface associated antikoerper, mucin 1, transmembrane antikoerper, MUC1 antikoerper, Muc1 antikoerper
- Hintergrund
- Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.
- Molekulargewicht
- 265-400 kDa
- Gen-ID
- 4582
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
-