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MUC1 Produkte

(Mucin 1 (MUC1))
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].

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Ausgewählte MUC1 Kategorien

MUC1 Antikörper

High quality antibodies with extensive validation data.

MUC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MUC1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MUC1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation IHC, WB, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7440383
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation IHC, WB, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7442027
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, WB, ELISA, FACS, ICC, Neut
Validierungen
  • (6)
Kat. Nr. ABIN5611324
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene MUC1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (6)
  • (5)
Kat. Nr. ABIN6730894
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968677
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968678
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MUC1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275298
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN1311631
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7013439
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MUC1 Produkten

El-Rasikh, Farghali, Abdelrahman, Elgaffary, Abdelmalek, Emam, Ghoneim, Selim: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).

Saleh, Harb, Soudani, Zaraket: "A three-dimensional A549 cell culture model to study respiratory syncytial virus infections." in: Journal of infection and public health, Vol. 13, Issue 8, pp. 1142-1147, (2020) (PubMed).

Szlendak, Sitarz, Berbecka, Mielko, Morsink, Maciejewski, Offerhaus, Polkowski: "Expression of cyclooxygenase-2 and mucin 1 in colorectal cancer." in: Molecular and clinical oncology, Vol. 13, Issue 5, pp. 52, (2020) (PubMed).

Zhang, Ji, Liu, Xu: "MUC1 downregulation promotes TNF-α-induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway." in: Journal of cellular physiology, (2019) (PubMed).

Milara, Díaz-Platas, Contreras, Ribera, Roger, Ballester, Montero, Cogolludo, Morcillo, Cortijo: "MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease." in: Respiratory research, Vol. 19, Issue 1, pp. 226, (2019) (PubMed).

Reuter, Alzheimer, Walles, Oelschlaeger: "An adherent mucus layer attenuates the genotoxic effect of colibactin." in: Cellular microbiology, Vol. 20, Issue 2, (2018) (PubMed).

Wang, Lu, Xie, Xiong, Huang, Wei, Jiang, Peng: "Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7." in: International immunopharmacology, Vol. 58, pp. 64-71, (2018) (PubMed).

Li, Zhou, Wei, Chen, Geng, Zheng, Chai, Li, Jiang: "miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor." in: Scientific reports, Vol. 6, pp. 27914, (2018) (PubMed).

Wang, Yuan, Wang, Yang, Chen, Liu, Song, Feng, Tan, Jia: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." in: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).

Wang, Duan, Wu, Min, Huang, Luo, He: "Effect of cyclooxygenase‑2 inhibition on the development of post‑traumatic stress disorder in rats." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 4925-4932, (2018) (PubMed).

Synonyme und alternative Namen zu MUC1

mucin 1, cell surface associated (MUC1), mucin 1, cell surface associated (Muc1), mucin 1, transmembrane (Muc1), CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, Muc-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM

Bezeichner auf Proteinebene für MUC1

  • DF3 antigen
  • H23 antigen
  • breast carcinoma-associated antigen DF3
  • cancer antigen 15-3
  • carcinoma-associated mucin
  • episialin
  • krebs von den Lungen-6
  • mucin 1, transmembrane
  • mucin-1
  • peanut-reactive urinary mucin
  • polymorphic epithelial mucin
  • tumor associated epithelial mucin
  • tumor-associated epithelial membrane antigen
  • tumor-associated mucin
  • endometrial mucin-1
  • epithelial mucin
  • MUC-1
  • Mucin1
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