ASXL1 Antikörper (Additional Sex Combs Like 1 (Drosophila)) (C-Term)

Details for Product anti-ASXL1 Antibody No. ABIN965603, Anbieter: Anmelden zum Anzeigen
Antigen
  • asxl1
  • MGC83850
  • mKIAA0978
  • BOPS
  • MDS
  • additional sex combs like 1 (Drosophila)
  • additional sex combs like 1
  • asxl1
  • LOC100341931
  • Asxl1
  • ASXL1
Epitop
C-Term
10
8
8
7
3
2
2
1
Reaktivität
Human, Maus
27
24
1
Wirt
Kaninchen
27
9
Klonalität
Polyklonal
Konjugat
Dieser ASXL1 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC)
31
21
18
17
15
7
5
3
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ASXL1(Putative Polycomb group protein ASXL1)
Reinigung Purified by antigen-specific affinity chromatography.
Andere Bezeichnung ASXL1 (ASXL1 Antibody Abstract)
Hintergrund ASXL1 is the Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. ASXL1 is widely expressed at low level and is highly expressed in testes. ASXL1 contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which may be required for an association with nuclear receptors.
Forschungsgebiet Chromatin and Nuclear Signaling
Pathways Retinoic Acid Receptor Signaling Pathway
Applikationshinweise ELISA, Western blotting: 1µg/ml for 2hrs.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Produkt verwendet in: Fisher, Berger, Randazzo, Brock: "A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11." in: Gene, Vol. 306, pp. 115-26, 2003 (PubMed).

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