FCAR Antikörper (Middle Region)

Produktnummer ABIN951425

Produktdetails anti-FCAR Antikörper

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Bindungsspezifität: AA 57-84, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FCAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 57-84 amino acids from the Central region of human FCAR

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Andere Bezeichnung: CD89 / FCAR (FCAR Produkte)

Synonyme: CD89 antikoerper, Fc fragment of IgA receptor antikoerper, Fc fragment of IgA, receptor for antikoerper, FCAR antikoerper

Hintergrund: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.Synonyms: IgA Fc receptor, Immunoglobulin alpha Fc receptor

Molekulargewicht: 32265 Da

Gen-ID: 2204

NCBI Accession: NP_001991