MAP2K4 Antikörper

Produktnummer ABIN932745

Der Maus Monoklonal anti-MAP2K4 Antikörper (Klon 2D10D8-4G11B2-2D10C4-2D10C3) (ABIN932745) detektiert spezifisch MAP2K4 in IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MAP2K4 Antikörper (ABIN932745)

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP2K4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Klon: 2D10D8-4G11B2-2D10C4-2D10C3

Produktdetails anti-MAP2K4 Antikörper

Immunogen: MAP2 K4 antibody was raised in Mouse using a purified recombinant fragment of MAP2 4 expressed in E. coli as the immunogen.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, IHC: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Details zu MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Andere Bezeichnung: MAP2K4

Hintergrund: MAP2K4 is a a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is adirect activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shownto activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. Synonyms: Monoclonal MAP2K4 antibody, Anti-MAP2K4 antibody, Mitogen-activated protein kinase kinase 4 antibody, MAPK/ERK kinase 4 antibody, MAPKK 4 antibody, SAPK/ERK kinase 1 antibody.

Pathways: MAPK Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling