MAGED1 Antikörper

Produktnummer ABIN871634

Produktdetails anti-MAGED1 Antikörper

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Aufreinigung: Affinity purified

Immunogen: Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Andere Bezeichnung: Melanoma-associated antigen D1 (MAGED1 Produkte)

Synonyme: MAGED1 antikoerper, DLXIN-1 antikoerper, NRAGE antikoerper, 2810433C11Rik antikoerper, 5430405L04Rik antikoerper, DXBwg1492e antikoerper, Dlixin antikoerper, Dlxin-1 antikoerper, Dlxin1 antikoerper, MAGE-D1 antikoerper, mFLJ00163 antikoerper, Nrage antikoerper, MAGE family member D1 antikoerper, melanoma antigen family D, 1 antikoerper, melanoma antigen, family D, 1 antikoerper, MAGED1 antikoerper, Maged1 antikoerper

Hintergrund: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

Molekulargewicht: 95 kDa

Gen-ID: 94275

NCBI Accession: NP_062765

UniProt: Q9QYH6

Pathways: Neurotrophin Signalübertragung