NR3C2 Antikörper (AA 601-700)
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- Target Alle NR3C2 Antikörper anzeigen
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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Bindungsspezifität
- AA 601-700
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Reaktivität
- Human, Ratte, Maus, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR3C2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
- Kreuzreaktivität
- Hund, Human, Maus, Ratte
- Homologie
- Cow,Pig,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Mineralocorticoid receptor
- Isotyp
- IgG
- Top Product
- Discover our top product NR3C2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).
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Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).
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- Target
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Andere Bezeichnung
- NR3C2/Mineralocorticoid receptor (NR3C2 Produkte)
- Synonyme
- mr antikoerper, si:ch211-189l17.1 antikoerper, LOC100302443 antikoerper, NR3C2 antikoerper, LOC443144 antikoerper, MLR antikoerper, MR antikoerper, MCR antikoerper, NR3C2VIT antikoerper, Mlr antikoerper, mlr antikoerper, nuclear receptor subfamily 3, group C, member 2 antikoerper, nuclear receptor subfamily 3 group C member 2 antikoerper, mineralocorticoid receptor antikoerper, nuclear receptor subfamily 3 group C member 2 L homeolog antikoerper, nr3c2 antikoerper, NR3C2 antikoerper, LOC443144 antikoerper, Nr3c2 antikoerper, nr3c2.L antikoerper
- Hintergrund
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Synonyms: MR, MCR, MLR, NR3C2VIT, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2, NR3C2
Background: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
- Gen-ID
- 4306
- UniProt
- P08235
- Pathways
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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