Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) Antikörper

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Antigen
  • erk1/2
  • mitogen-activated protein kinase
  • erk1/2
Epitop
pThr183, pTyr185, AA 160-200
129
127
35
34
29
19
18
15
15
15
15
14
11
9
9
9
9
8
6
5
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus), Rind (Kuh)
421
320
304
56
23
15
9
8
8
7
7
6
5
5
3
3
2
2
2
1
1
1
1
Wirt
Kaninchen
349
78
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
12
11
11
10
7
7
7
7
6
6
6
6
6
6
2
2
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
305
114
83
77
59
56
46
42
16
10
6
4
4
4
2
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185
Isotyp IgG
Reinigung Purified by Protein A.
Andere Bezeichnung ERK1, ERK2 (MAPK1/3 Antibody Abstract)
Sub Type Cocktail
Hintergrund

Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity).

Subcellular location: Cytoplasm

Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk

Gen-ID 26413
UniProt P63085
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) antibody (ABIN687727) Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Rabbit Anti-ERK...
SDS-PAGE (SDS) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) antibody (ABIN687727) L1 rat liver lysates L2 rat kidney lysates probed with Rabbit Anti-ERK1 (Thr203/Tyr20...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 160-200), (pThr183), (pTyr185) antibody (ABIN687727) Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Rabbit Anti-ERK...
Produkt verwendet in: Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, 2016 (PubMed).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, 2015 (PubMed).

Rosenzweig, Djap, Ou, Quinn: "Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 12, pp. 1591-602, 2012 (PubMed).

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